A system (10) and a method (100) compensate for one or more dead pixels in positron emission tomography (PET) imaging. A pixel compensation processor receives PET data describing a target volume of a subject. The PET data is missing data for one or more dead pixels. The pixel compensation estimates PET data for the dead pixels from the received PET data.

Methods and systems are provided for performing cathode calibration in a detector assembly. In one embodiment, a method comprises adjusting a cathode bias of a detector based on a total number of events occurring in the detector during a time period while maintaining an anode bias at a desired value, the events corresponding to photon energy detected by the detector. In this way, an automated cathode calibration procedure may be applied to calibrate the detector assembly.

A detector of a gamma camera is configured such that a radioactive point source is positioned within a field of view at a fixed distance from the detector. A predetermined number of gamma photons emitted by the point source and passed through a collimator are acquired. A system-specific planar sensitivity is computed for a combination of the collimator and detector using the number of gamma photons acquired, a time duration of the acquisition, and precalibrated radioactivity data of the point source corrected for decay that occurred after a precalibration time. A deviation of the computed system-specific planar sensitivity from a class standard sensitivity value for a combination of the radioactive point source, the collimator, and the detector is computed. A class standard sensitivity value for a combination of a radiopharmaceutical, the collimator, and the detector is scaled by the computed deviation, yielding a scaled system-specific sensitivity value for the radiopharmaceutical.

Provided is a radiation detector including a scintillator which generates, when a radial ray enters, scintillation light having light intensity according to energy of the radial ray, and then supplies a photon of the scintillation light to each of a plurality of pixels, a radial ray detection unit which detects whether or not the radial ray is made to enter based on a number of the photons supplied in an exposure period whenever the plurality of pixels are exposed by the scintillation light over the exposure period, and an exposure period adjusting unit which adjusts the exposure period based on an incident frequency of the detected radial ray.

An apparatus, method, computer-readable medium, and system for adjusting data acquisition parameters during a scan performed by a Positron Emission Tomography (PET) scanner. The method includes obtaining, during the scan, a current temperature of a detector of the PET scanner, and adjusting, based on the current temperature, the data acquisition parameters used by the PET scanner during the scan.

A photon detector for use in imaging, comprising a detector surface for detecting photons incident on the detector surface, the detector surface comprising at least one non-flat feature configured such that, during imaging, at least a portion of the photons are blocked from incidence upon at least a portion of the detector surface.

A medical nuclear imaging system (10) and corresponding method (100) are provided. A plurality of pixels (20, 24) detect radiation events and estimate the energy of the detected radiation events. A memory (58) stores a plurality of energy windows (44), the energy windows corresponding to the pixels. An event verification module (56) windows the radiation event with the energy windows corresponding to the detecting pixels. A reconstruction processor (60) reconstructs the windowed radiation events into an image representation.

Gamma-ray detectors for the detection of one or more gamma-rays are provided. Also provided are methods of using the detectors for the detection of one or more gamma-rays. The detectors can be used in high-spatial resolution PET systems, including time-of-flight (TOF)-PET systems. Some of the gamma-ray detectors utilize fluors and an optical imaging system to determine the time and location of a first scattering event of a gamma-ray in a low atomic number scintillating medium. Some of the gamma-ray detectors determine the time and location of a first scattering event of a gamma-ray in a low-density scintillating medium by imaging scintillation photons from the scattering event as a time-series of photon rings using a planar pixelated photodetector as a scintillation photon counter.

A method includes accumulating counts for each pixel in a set of pixels of one or more gamma cameras of a SPECT imaging system from a plurality of imaging examinations and each energy peak of each isotope used in the plurality of imaging examinations to produce an energy spectrum for each of the pixels at each of the energy peaks of each of the isotopes, determining, for the pixels and for the energy peaks, an energy calibration factor that converts an energy detected by each of the pixels to an energy of a corresponding energy peak and populating an energy map with the factors, and determining, for the pixels and for the energy peaks, a uniformity calibration factor that converts a number of counts detected by each of the pixels to a predetermined number of counts for a corresponding energy peak and populating a uniformity map with the factors.

A nuclear medicine diagnostic device according to an embodiment includes processing circuitry. The processing circuitry obtains first photon-number information detected by a first detector; calculates, based on the first photon-number information, a first light emission probability model corresponding to the first detector; identifies, based on the first light emission probability model, a first timing at which the detection probability becomes equal to or greater than a predetermined threshold value; measures the detection timing of an event detected by the first detector; and corrects the detection timing based on the first timing.