Patent classifications
A61K6/853
Delivery system for providing self-hardening calcium silicate based compositions used in medical applications
Delivery and/or injection systems, preferably for medical applications. Especially, a kit of parts for providing a dental composition able to self-hardening. The kit of parts includes a first waterproof container including an anhydrous calcium silicate phase; and a second container including an aqueous phase. The kit of parts may be used in delivery and/or injection systems so that it delivers a homogenous calcium silicate-based composition having a volume ratio between the calcium silicate phase and the aqueous phase ranging from 1 to 3. Also, the hardened material obtained from the kits of parts, the delivery and/or injection system.
DELIVERY SYSTEM FOR PROVIDING SELF-HARDENING CALCIUM SILICATE BASED COMPOSITIONS USED IN MEDICAL APPLICATIONS
Delivery and/or injection systems, preferably for medical applications. Especially, a kit of parts for providing a dental composition able to self-hardening. The kit of parts includes a first waterproof container including an anhydrous calcium silicate phase; and a second container including an aqueous phase. The kit of parts may be used in delivery and/or injection systems so that it delivers a homogenous calcium silicate-based composition having a volume ratio between the calcium silicate phase and the aqueous phase ranging from 1 to 3. Also, the hardened material obtained from the kits of parts, the delivery and/or injection system.
DELIVERY SYSTEM FOR PROVIDING SELF-HARDENING CALCIUM SILICATE BASED COMPOSITIONS USED IN MEDICAL APPLICATIONS
Delivery and/or injection systems, preferably for medical applications. Especially, a kit of parts for providing a dental composition able to self-hardening. The kit of parts includes a first waterproof container including an anhydrous calcium silicate phase; and a second container including an aqueous phase. The kit of parts may be used in delivery and/or injection systems so that it delivers a homogenous calcium silicate-based composition having a volume ratio between the calcium silicate phase and the aqueous phase ranging from 1 to 3. Also, the hardened material obtained from the kits of parts, the delivery and/or injection system.
STRONTIUM-DOPED ROOT CANAL FILLING PASTE, PREPARATION METHOD THEREFOR AND USE THEREOF
A strontium-doped root canal filling paste, a preparation method therefor and use thereof in the treatment of dental pulp disease are provided. The strontium-doped root canal filling paste includes a component (a) and a component (b), wherein component (a) is selected from calcium silicate compounds, and component (b) is selected from strontium compounds. Component (a) accounts for 20%-40% of by weight of the paste, and component (b) accounts for 0.5%-10% by weight of the paste; and components (a) and (b) are doped in a physical doping manner.
STRONTIUM-DOPED ROOT CANAL FILLING PASTE, PREPARATION METHOD THEREFOR AND USE THEREOF
A strontium-doped root canal filling paste, a preparation method therefor and use thereof in the treatment of dental pulp disease are provided. The strontium-doped root canal filling paste includes a component (a) and a component (b), wherein component (a) is selected from calcium silicate compounds, and component (b) is selected from strontium compounds. Component (a) accounts for 20%-40% of by weight of the paste, and component (b) accounts for 0.5%-10% by weight of the paste; and components (a) and (b) are doped in a physical doping manner.
Preparation and fully compounded stock for use in medical or dental applications, medical or dental product and use and preparation thereof
According to the invention, a preparation is described which contains at least one calcium compound selected from the group consisting of calcium phosphates, calcium fluorides and calcium fluorophosphates and hydroxyl derivatives and carbonate derivatives of these calcium salts, calcium hydroxides and calcium oxides precipitated using at least one protein component selected from proteins and protein hydrolysates, and at least one crosslinking agent for the protein component and/or non-set cement.
Preparation and fully compounded stock for use in medical or dental applications, medical or dental product and use and preparation thereof
According to the invention, a preparation is described which contains at least one calcium compound selected from the group consisting of calcium phosphates, calcium fluorides and calcium fluorophosphates and hydroxyl derivatives and carbonate derivatives of these calcium salts, calcium hydroxides and calcium oxides precipitated using at least one protein component selected from proteins and protein hydrolysates, and at least one crosslinking agent for the protein component and/or non-set cement.
DENTAL CURABLE COMPOSITION, DENTAL BLANK FOR CUTTING, METHOD OF PRODUCING A SILICA COMPOSITE OXIDE PARTICULATE, AND DENTAL FILLER
[Object] To provide a dental blank for cutting, which includes a to-be-cut portion formed of a hybrid resin that includes a spherical particle of a silica composite oxide and has an external color unlikely to change depending on a thickness.
[Solving Means] When a raw material solution in which a condensable compound such as tetraethyl silicate and tetra(n-butoxy)zirconate is dissolved is added to a basic solution to precipitate a silica composite oxide particulate of a silica composite oxide, a cured body of a dental curable composition that includes 100 to 800 parts by mass of a silica composite oxide particulate with respect to 100 parts by mass of a radically polymerizable monomer is used as a to-be-cut portion, the silica composite oxide particulate being obtained by controlling a solvent composition of each of the solutions, including a spherical particle of a silica composite oxide, and having an average primary particle size of 350 to 600 nm, the spherical particle having a silica content ratio of 80 to 92 mol % and including no silica core.
DENTAL CURABLE COMPOSITION, DENTAL BLANK FOR CUTTING, METHOD OF PRODUCING A SILICA COMPOSITE OXIDE PARTICULATE, AND DENTAL FILLER
[Object] To provide a dental blank for cutting, which includes a to-be-cut portion formed of a hybrid resin that includes a spherical particle of a silica composite oxide and has an external color unlikely to change depending on a thickness.
[Solving Means] When a raw material solution in which a condensable compound such as tetraethyl silicate and tetra(n-butoxy)zirconate is dissolved is added to a basic solution to precipitate a silica composite oxide particulate of a silica composite oxide, a cured body of a dental curable composition that includes 100 to 800 parts by mass of a silica composite oxide particulate with respect to 100 parts by mass of a radically polymerizable monomer is used as a to-be-cut portion, the silica composite oxide particulate being obtained by controlling a solvent composition of each of the solutions, including a spherical particle of a silica composite oxide, and having an average primary particle size of 350 to 600 nm, the spherical particle having a silica content ratio of 80 to 92 mol % and including no silica core.
Pre-mixed strontium silicate-based biological hydraulic cementing paste composition, preparation method therefor, and application thereof
A pre-mixed strontium silicate-based biological hydraulic cement paste composition and preparation method and use thereof are disclosed. The pre-mixed strontium silicate-based biological hydraulic cement paste of the disclosure uses strontium silicate as the main phase and at least one non-aqueous solvent that is miscible with water, and preferably, it may further include at least one calcium phosphate compound and at least one radiopaque material, to prepare a biological hydraulic cement paste with excellent injectability. The material remains as a fluid under a sealed condition, and hydrates, solidifies and hardens when it is placed in a physiological environment and contacts with a physiological body fluid. The strontium silicate-based material having excellent biocompatibility and biological activity is used to prepare a pre-mixed strontium silicate-based cement paste, which can be used for medical and dental applications including fields of pulp capping, root canal therapy, dental restorations and the like.