A61K6/876

Monolithic bodies of sintered chemically bonded ceramic (CBC) biomaterial prepared ex vivo for implantation, preparation and use thereof
10117964 · 2018-11-06 · ·

The present invention generally relates to the use of pre-formed bodies of Chemically Bonded Ceramics (CBCs) biomaterial for implantation purposes wherein the bodies are prepared ex vivo allowing process parameters to be optimized for desired long term properties of the resulting CBC biomaterial. More particularly, the pre-formed CBC material bodies of the present invention are sintered. The pre-formed body of CBC material is machined to the desired geometry and then implanted using a CBC cementation paste for fixation of the body to tissue. The invention also relates to a method of preparing pre-formed bodies of CBC biomaterial for implantation purposes, methods of preparing an implant thereof having desired geometry, and a method of implantation of the implant, as well as a kit for use in the method of implantation.

Coated dental articles and related methods of manufacture

Provided are dental articles, and methods of making articles, having an aesthetic inorganic coating based on zirconia at least partially stabilized with yttrium oxide, calcium oxide, cerium oxide, or magnesium oxide. Stabilized zirconia coatings were found to provide a smooth, low friction surface having high abrasion resistance. These coatings are particularly applicable to orthodontic appliances. While virgin stabilized zirconia coatings can often have an undesirable color cast, it was discovered that this color cast can be substantially eliminated by heat treating the coated appliance in an oxygenated environment. The combination of depositing a stabilized zirconia coating and subsequently heat treating to decolorize the coating provides a surprisingly robust, stable, low-friction coating that is also aesthetic.

COMPOSITIONS AND METHODS FOR ADHESION TO SURFACES
20180085490 · 2018-03-29 ·

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

Methods of treatment of the dental pulp and filling root canals using water-based material

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; wherein the particulate material has an average particle size of less than 40 microns; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, and (ii) water.

DENTAL SELF-ADHESIVE RESIN CEMENT
20180078465 · 2018-03-22 ·

A dental self-adhesive resin cement is provided comprising a two-component system. A first catalyst component includes one or more acidic monomers. A second base component includes one or more basic fillers. The mixture of the first and second components is polymerizable and has an initial pH that is acidic immediately after mixing and a pH of at least about pH 8 after polymerization.

Bioactive medical ceramic cement
12171898 · 2024-12-24 · ·

Bioactive, ceramic medical cements and methods for its use in treatment of bones and teeth in mammals are disclosed. This cement is non-exothermic and non-toxic, based upon setting of hydraulic ceramic compounds containing calcia, alumina, and silica phases. The self-hardening cement sets in vivo and in high humidity environments, and can be used in vivo without being easily washed out of the site. It also has dimensional stability, is resistant to acids present in an infection site or supragingivally, and has biocompatibility advantages of low inflammation and the formation of calcification layers in direct apposition to body tissue. Options include the addition of various radiopaque materials, and a variety of delivery systems including powder and liquid, capsule or pouch delivery, multiple pastes, or a unitary paste.

Bioactive medical ceramic cement
12171898 · 2024-12-24 · ·

Bioactive, ceramic medical cements and methods for its use in treatment of bones and teeth in mammals are disclosed. This cement is non-exothermic and non-toxic, based upon setting of hydraulic ceramic compounds containing calcia, alumina, and silica phases. The self-hardening cement sets in vivo and in high humidity environments, and can be used in vivo without being easily washed out of the site. It also has dimensional stability, is resistant to acids present in an infection site or supragingivally, and has biocompatibility advantages of low inflammation and the formation of calcification layers in direct apposition to body tissue. Options include the addition of various radiopaque materials, and a variety of delivery systems including powder and liquid, capsule or pouch delivery, multiple pastes, or a unitary paste.

Compositions and methods for adhesion to surfaces
12178937 · 2024-12-31 · ·

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

Compositions and methods for adhesion to surfaces
12178937 · 2024-12-31 · ·

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

Hardenable dental compositions comprising basic core material encapsulated in an inorganic shell and dispensing devices therewith

A hardenable (e.g. dental) compositions is described comprising an encapsulated material. The encapsulated material comprises a basic core material and an inorganic shell material having certain viscosity criteria. Also described are dispensing devices and kits are described comprising a hardenable (e.g. dental) composition comprising a liquid material and an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core. The dispensing devices and kits can facilitate the methods of applying the hardenable composition. The hardenable or hardened (e.g. cured) composition can provide various technical effects such as a delayed release of a basic core material, a delayed increase in basicity, promoting remineralization of a tooth or bone structure, and increasing the average alkaline phosphatase (ALP) activity of pulp cells. In some embodiments, the composition is a dental (e.g. sealant) composition for application to a tooth structure.