A61K6/891

Dental composition
10596078 · 2020-03-24 · ·

Dental composition comprising (a) at least two di- or polyepoxides having 2 to 5 epoxide groups and having a molecular weight of from 200 to 700 Da, or a macromonomeric reaction product obtainable by reacting the diepoxide with a dicarboxylic acid in a molar ratio [diepoxide]/[dicarboxylic acid] of at least 2; (b) one or more primary monoamines and/or disecondary diamines; (c) optionally one or more aliphatic polyamines; (d) a particulate filler, wherein the molar ratio of epoxide groups in component (a) to the NH bonds in component (b) and (c) [epoxide.sub.(a)]/[NH.sub.(b),(c)] is in the range of from 0.9 to 1.1; wherein the di- or polyepoxide having 2 to 5 epoxide groups is a compound of the following formula (I):
A(BZ.sub.m).sub.n(I) wherein A represents an n-valent organic moiety optionally having 1 to 10 heteroatoms selected from oxygen atoms and sulfur atoms; and B represents an m+1-valent organic moiety, Z is an epoxide group which may have a substituent, m which are independent from each other represent an integer of at least 1; and n is an integer of from 1 to 5; wherein the m are selected so that 2 to 5 epoxide groups are present; wherein the composition does not contain any 2,2-bis-(4-hydroxyphenyl)-propane, or 2,2-bis-(4-hydroxyphenyl)-methane.

Dental composition
10596078 · 2020-03-24 · ·

Dental composition comprising (a) at least two di- or polyepoxides having 2 to 5 epoxide groups and having a molecular weight of from 200 to 700 Da, or a macromonomeric reaction product obtainable by reacting the diepoxide with a dicarboxylic acid in a molar ratio [diepoxide]/[dicarboxylic acid] of at least 2; (b) one or more primary monoamines and/or disecondary diamines; (c) optionally one or more aliphatic polyamines; (d) a particulate filler, wherein the molar ratio of epoxide groups in component (a) to the NH bonds in component (b) and (c) [epoxide.sub.(a)]/[NH.sub.(b),(c)] is in the range of from 0.9 to 1.1; wherein the di- or polyepoxide having 2 to 5 epoxide groups is a compound of the following formula (I):
A(BZ.sub.m).sub.n(I) wherein A represents an n-valent organic moiety optionally having 1 to 10 heteroatoms selected from oxygen atoms and sulfur atoms; and B represents an m+1-valent organic moiety, Z is an epoxide group which may have a substituent, m which are independent from each other represent an integer of at least 1; and n is an integer of from 1 to 5; wherein the m are selected so that 2 to 5 epoxide groups are present; wherein the composition does not contain any 2,2-bis-(4-hydroxyphenyl)-propane, or 2,2-bis-(4-hydroxyphenyl)-methane.

Fixture and implant
10588719 · 2020-03-17 · ·

A fixture (10) to be embedded in a bone (H), comprising: a fixture body (11) through which a central hole (13) penetrates over the entire length thereof; and a cap body (21) which closes an opening on a root end side of the central hole (13). The cap body (21) has a first shaft section (24) to be fitted into the central hole (13). The central hole (13) has a first tapered hole section (14) which decreases in diameter from the root end side toward a top end side, and the cap body (21) has a first tapered shaft section (25) to be fitted into the first tapered hole section (14).

RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES

Radically polymerizable dental material, which includes a catalyst paste and a base paste, wherein the catalyst pastes includes an oxidizing agent, preferably a peroxide or hydroperoxide, a radically polymerizable monomer and/or oligomer with acid group and a polyfunctional radically polymerizable monomer, and the base paste comprises a polyfunctional radically polymerizable monomer without an acid group and a dihydropyridine derivative of Formula (1)

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The material has good mechanical properties and does not exhibit a bitter taste.

RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES

Radically polymerizable dental material, which includes a catalyst paste and a base paste, wherein the catalyst pastes includes an oxidizing agent, preferably a peroxide or hydroperoxide, a radically polymerizable monomer and/or oligomer with acid group and a polyfunctional radically polymerizable monomer, and the base paste comprises a polyfunctional radically polymerizable monomer without an acid group and a dihydropyridine derivative of Formula (1)

##STR00001##

The material has good mechanical properties and does not exhibit a bitter taste.

METHOD OF REDUCING BACTERIAL ACTIVITY IN THE ORAL CAVITY OF A PATIENT

Base material arrangements having at least two layers can accommodate the addition of antifungal material (nanofiller), such as in denture base resin without significantly compromising the mechanical properties and/or translucency of the base material arrangements. Antifungal agents such as nanosilver and nanozirconia can be used to modify a surface layer of the material arrangements, such as the denture base, to overcome certain known shortcomings of the modified materials, e.g., typical acrylic resins containing nanosilver and nanozirconia.

METHOD OF REDUCING BACTERIAL ACTIVITY IN THE ORAL CAVITY OF A PATIENT

Base material arrangements having at least two layers can accommodate the addition of antifungal material (nanofiller), such as in denture base resin without significantly compromising the mechanical properties and/or translucency of the base material arrangements. Antifungal agents such as nanosilver and nanozirconia can be used to modify a surface layer of the material arrangements, such as the denture base, to overcome certain known shortcomings of the modified materials, e.g., typical acrylic resins containing nanosilver and nanozirconia.

Polyphenols/PEG based hydrogel system for a dental varnish
10500138 · 2019-12-10 · ·

Described herein are dental treatment compositions, more particularly, a dental varnish composition useful in effective fluoridation, enhancement of remineralization the tooth enamel, and hypersensitivity through occlusion of dentine tubule. The dental varnish composition includes a hydrogel system and at least one fluoride source, wherein the dental varnish is water soluble. The hydrogel system includes at least one polyphenol having at least one phenol group, at least one polymer, and a metal ion. Described herein are also methods of making such dental varnish composition.

Root canal filler composition and method for preparing same

The present disclosure provides a root-canal sealer composition including cement and a hygroscopic liquid, in which the cement includes tricalcium silicate (3CaO.Math.SiO.sub.2) in which an aluminum atom (Al) is solid-soluted (Al solid-soluted C3S), dicalcium silicate (2CaO.Math.SiO.sub.2) in which an aluminum atom (Al) is solid-soluted (Al solid-soluted C2S), and tricalcium aluminate (3CaO.Math.Al.sub.2O.sub.3) in which a silicon atom (Si) is solid-soluted (Si solid-soluted C3A), the tricalcium aluminate being disposed between at least one selected from the group consisting of the Al solid-soluted C3S and the Al solid-soluted C2S. When the cement including aluminum solid-soluted tricalcium silicate, aluminum solid-soluted dicalcium silicate, and silicon solid-soluted tricalcium aluminate is prepared and used for a root-canal sealer composition, a curing time is reduced and compressive strength is increased. Also, the root-canal sealer composition is effective at ensuring a sufficient working time, thereby improving workability and storage stability.

POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME
20240122815 · 2024-04-18 ·

A polymerizable compound is represented by the formula (I). Each R.sup.1 independently represents a monovalent group having from 3 to 12 carbon atoms that comprises at least one of an epoxy group, an acryl group, or a methacryl group. Each R.sup.2 independently represents H, F, Cl, Br, C.sub.1-C.sub.12 alkyl, C.sub.2-C.sub.3 carbonylalkyl, or C.sub.2-C.sub.5 carboalkoxy. Each R.sup.3 independently represents C H, F, Cl, Br, C.sub.1-C.sub.12 alkyl, C.sub.2-C.sub.3 carbonylalkyl, or C.sub.2-C.sub.5 carboalkoxy. Each n is independently 0, 1, 2, 3, or 4. Curable compositions including the polymerizable compound are also disclosed.

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