A nanoparticle composition for oral care includes at least one of a first set of spherical nanoparticles or a second set of coral shaped nanoparticles, and a stabilizing agent. The nanoparticle composition is added to a carrier suitable for application to an oral cavity, including to teeth and surrounding oral tissues. The nanoparticle composition is configured to control the pH of the microenvironment to which it is applied, thereby preventing and/or treating a variety of oral conditions. The nanoparticle composition can be provided as a concentrated nanoparticle additive addable to a mouthwash, mouth rinse, dentifrice, mouth spray, oral gel, denture cleaning solution, or other carrier suitable for oral application.

The disclosure provides a peptide microparticle structure that can easily penetrate into the bottom layer of the skin. The peptide microparticle structure is composed, from inside to outside, of a main core, a first lipid layer, an active ingredient layer, and a second lipid layer. The main core is disposed at the center of the peptide microparticle structure, and the outer part of the main core is completely covered by the first lipid layer. The outermost layer of the peptide microparticle structure is the second lipid layer, and between the first lipid layer and the second lipid layer is the active ingredient layer.

Disclosed is a dissolvable solid article, comprising by weight of the article: from about 10% to about 50% of a water soluble polymer; from about 20% to about 80% of a surfactant; from about 0.5% to about 2% of diaminocarboxylic acid chelants and salts thereof having an average molecular weight in acid form of from about 250 to about 450 daltons and having a weighted log P value at pH 4 of from about −12 to about −7; from about 0.1% to about 6% of an aromatic carboxylic acid and salts thereof having an average molecular weight in acid form of from about 100 to about 400 daltons and having a weighted log P value at pH 4 of from about −2 to about 4; from about 0.1% to about 18% of an non-aromatic organic alpha hydroxy acid and salts thereof; wherein the dissolvable solid article has a pH of from about 3 to about 5.1 when dissolved with 30 parts water to 1 part of the dissolvable solid article. The present invention provides dissolvable solid articles which provide anti-bacterial benefit even after dissolution of the articles, while controlling the concentration of anti-bacterial active ingredients in the solid articles.

A composition including ascorbic acid, a silicone oil, and at least 15% by weight of an essential oil is disclosed. At least 50% of the initial amount of ascorbic acid in the non-aqueous composition can remain stable when the composition is stored for at least 1 month at room temperature.

A method of emulsification of an oil phase in an aqueous continuous phase, by dispersing core-corona microparticles into the aqueous phase, adding the oil phase, and applying shearing force for a time sufficient to emulsify the resulting mixture. The core-corona microparticles are obtained by radical co-polymerization of a polyethylene oxide macromonomer with at least one hydrophobic acrylate monomer and at least one hydrophobic acrylamide monomer.

The present invention relates to a process for preparing a crystalline merocyanine compound, comprising the step of dissolving a merocyanine compound in an organic, polar solvent, wherein the process is performed at a pH below than 7 in the presence of an acid, wherein residual levels of colored impurities are eliminated.

A rheological solid composition comprising a crystallizing agent and an aqueous phase.

The invention relates to lipophilic transport particles for cosmetic or pharmaceutical active ingredients. The lipophilic transport particles comprise polyglycerol fatty acid ester as a main constituent and, because of the absence of polymorphic transformations, even during long storage, neither have volume changes nor allow the problem of expulsion of the adhering or enclosed active ingredient, due to intense structuring of the crystal lattice and associated compaction, to arise, and therefore the degree of loading with active ingredient and the release profile are stable.

Rheological solid self-supporting liquid expressing composition comprising more than 80% water having a crystallizing agent, suspension agent, and insoluble active.

Unit-dose oral care composition comprising a fibrous composition and/or an open cell foam with a low level of inorganic salts. Oral care compositions that dissolve quickly upon initial contact with water. Oral care compositions which leave a low amount of residue on surfaces upon use. Methods of use of unit-dose oral care compositions.