The present disclosure provides an oral care composition including a water-miscible base component, an amorphous calcium phosphate remineralizing component including a water-soluble or partially water-soluble calcium component and a water-soluble inorganic phosphate component, and a tartar control component, wherein the oral care composition provides enamel fluoride uptake activity and tartar control activity.

The present disclosure provides an oral care composition including a water-miscible base component, an amorphous calcium phosphate remineralizing component including a water-soluble or partially water-soluble calcium component and a water-soluble inorganic phosphate component, and a tartar control component, wherein the oral care composition provides enamel fluoride uptake activity and tartar control activity.

The present invention relates to a tooth whitening composition, which comprises a reducing agent partially encapsulated in liposomes. It relates also to a method for preparing that tooth whitening composition and to the non-therapeutic cosmetic use of that composition for tooth whitening.

Selected peptides have been found to repair, by means of nucleotide excision repair (NER), cellular DNA damaged by the exposure to external agents, in particular UV rays and are useful for cosmetic or pharmaceutical use thereof in skin treatment. Compositions for topical application that contain such peptides, preferably carried in liposomes, prevent and treat skin damage caused by the exposure to UV rays, including in subjects affected by xeroderma pigmentosum.

In one aspect, the application relates to novel aqueous oral care compositions useful for combining and delivering potassium salts and a basic amino acid in a high-water composition, for example, to naturally promote nitrate reduction from the oral microbiome, which can result in systemic increases of nitric oxide in blood plasma and can form part of an overall regimen to maintain, reduce, treat or control systemic blood pressure.

In one aspect, the application relates to novel aqueous oral care compositions useful for combining and delivering potassium salts and a basic amino acid in a high-water composition, for example, to naturally promote nitrate reduction from the oral microbiome, which can result in systemic increases of nitric oxide in blood plasma and can form part of an overall regimen to maintain, reduce, treat or control systemic blood pressure.

The present invention provides new dental care products comprising self-assembling peptides that are capable of undergoing self-assembly at a certain pH that are useful in dental care, in particular, useful for reducing or preventing demineralisation of teeth of a subject, in particular, for reducing or preventing further demineralisation of teeth of a subject. The dental care products comprises self-assembling peptides, in particular, comprise self-assembling peptides comprising the sequence of SEQ ID NO: 21, that are capable of undergoing self-assembly at a pH below 7.5, wherein the self-assembling peptides are essentially present in the dental care product in assembled form, and a pharmaceutically acceptable basis. The dental care product is an essentially solid product selected from the group consisting of chewing gum, soft chew, toffee, gelatin gum, chewy candy, chew toy, lozenge. Preferably, it is a chewy product. The dental care product is not abrasive. The dental care product is useful for reducing or preventing (further) demineralisation of a tooth surface of a subject with demineralised teeth, e.g., or a subject with xerostomia, hyopsalivation, bruxism, gastroesophageal reflux disease, dentine hypersensitivity and/or tooth erosion. Preferably, it is also useful for cleaning the tooth surface. Products of the invention are useful for animals and humans. The invention also provides a process for preparing the dental care products of the invention. The invention enables non-targeted treatment of a plurality of teeth, and it is independent of the diagnosis of caries.

The present invention provides new dental care products comprising self-assembling peptides that are capable of undergoing self-assembly at a certain pH that are useful in dental care, in particular, useful for reducing or preventing demineralisation of teeth of a subject, in particular, for reducing or preventing further demineralisation of teeth of a subject. The dental care products comprises self-assembling peptides, in particular, comprise self-assembling peptides comprising the sequence of SEQ ID NO: 21, that are capable of undergoing self-assembly at a pH below 7.5, wherein the self-assembling peptides are essentially present in the dental care product in assembled form, and a pharmaceutically acceptable basis. The dental care product is an essentially solid product selected from the group consisting of chewing gum, soft chew, toffee, gelatin gum, chewy candy, chew toy, lozenge. Preferably, it is a chewy product. The dental care product is not abrasive. The dental care product is useful for reducing or preventing (further) demineralisation of a tooth surface of a subject with demineralised teeth, e.g., or a subject with xerostomia, hyopsalivation, bruxism, gastroesophageal reflux disease, dentine hypersensitivity and/or tooth erosion. Preferably, it is also useful for cleaning the tooth surface. Products of the invention are useful for animals and humans. The invention also provides a process for preparing the dental care products of the invention. The invention enables non-targeted treatment of a plurality of teeth, and it is independent of the diagnosis of caries.

In one aspect, the present disclosure relates to oral care compositions comprising a source of zinc, a fluoride source, a zwitterionic surfactant and a taurate surfactant. In one aspect the compositions of the disclosure can be used for the treatment or reduction of erosive tooth demineralization, gingivitis, plaque, and dental caries. In one aspect the oral care composition includes zinc citrate, zinc oxide, arginine, cocamidopropyl betaine and at least one taurate surfactant (e.g., sodium methyl cocoyl taurate).

An oral care composition containing a gel phase, an abrasive, and a fluoride source. The gel network phase contains a cold dispersible fatty amphiphile and phase separation is not visually perceptible in the oral care composition.