The disclosure relates to compositions comprising (a) at least one polyphenol; (b) at least one film former; (c) at least one gum; (d) at least one emulsifier; (e) at least one fatty alcohol; and (f) at least one solvent. Optionally, the compositions may further comprise at least one humectant and/or at least one fatty acid. The compositions can be used for styling hair, for example temporarily straightening the hair and/or for reducing frizz of hair. The disclosure also relates to methods of using the compositions to style hair, straighten hair, and/or reduce frizz of hair.

High penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capable of being converted to parent drugs or parent drug-related compounds such as metabolites after crossing one or more biological barriers and thus can render treatments for the conditions that the parent drugs or parent drug-related compounds can. Additionally, the HPCs are capable of reaching areas that their parent drugs or parent drug-related compounds may not be able to access or to render a sufficient concentration at the target areas HPCs of NSAIA, for example, have demonstrated indications such as treating hair loss. A HPC can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

High penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capable of being converted to parent drugs or parent drug-related compounds such as metabolites after crossing one or more biological barriers and thus can render treatments for the conditions that the parent drugs or parent drug-related compounds can. Additionally, the HPCs are capable of reaching areas that their parent drugs or parent drug-related compounds may not be able to access or to render a sufficient concentration at the target areas HPCs of NSAIA, for example, have demonstrated indications such as treating hair loss. A HPC can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

A low-viscosity water-in-oil cosmetic emulsion preparation gives a smooth use feeling, lightly spreads when applied, and has excellent dispersed-powder stability. The cosmetic emulsion preparation has (A) a polar oil which is liquid at 25° C. and has an IOB value exceeding 0.1, (B) a hydrocarbon oil, (C) a polyoxyalkylene; and alkyl-modified organopolysiloxane represented by general formula (I), and (D) a powder surface-treated with both an N-acylamino acid and methylpolysiloxane. (In formula (I), R represents a hydrogen atom or a C1-5 alkyl group, x is an integer of 5-50, y is an integer of 1-30, z is an integer of 20-200, a is an integer of 2-20, b is an integer of 1-5, c is an integer of 2-20, and d is an integer of 0-20). ##STR00001##

A low-viscosity water-in-oil cosmetic emulsion preparation gives a smooth use feeling, lightly spreads when applied, and has excellent dispersed-powder stability. The cosmetic emulsion preparation has (A) a polar oil which is liquid at 25° C. and has an IOB value exceeding 0.1, (B) a hydrocarbon oil, (C) a polyoxyalkylene; and alkyl-modified organopolysiloxane represented by general formula (I), and (D) a powder surface-treated with both an N-acylamino acid and methylpolysiloxane. (In formula (I), R represents a hydrogen atom or a C1-5 alkyl group, x is an integer of 5-50, y is an integer of 1-30, z is an integer of 20-200, a is an integer of 2-20, b is an integer of 1-5, c is an integer of 2-20, and d is an integer of 0-20). ##STR00001##

The present disclosure provides a composition for hair and fiber treatment which supplies a transition metal as a catalyst to a thiol residue formed when hair or fiber is damaged in a process of chemical or physical care, and rapidly and abundantly binds an olefin-based unsaturated hydrocarbon through a thiol-ene reaction, thereby continuously providing smoothness to the hair and fiber.

The present disclosure provides a composition for hair and fiber treatment which supplies a transition metal as a catalyst to a thiol residue formed when hair or fiber is damaged in a process of chemical or physical care, and rapidly and abundantly binds an olefin-based unsaturated hydrocarbon through a thiol-ene reaction, thereby continuously providing smoothness to the hair and fiber.

A skin cleansing agent containing the following components (A), (B), and (C): a particle (A) including (A1), (A2), and (A3), (A1) a water-holding oil agent in an amount of from 0.0001 to 13 mass % in the skin cleansing agent, (A2) a moisturizing agent in an amount of from 0.001 to 25 mass % in the skin cleansing agent, and (A3) a polymer; a surfactant (B); and water (C).

Provided is a composition for forming a coating film directly on the skin by an electrostatic spray, the composition being capable of forming a coating film having excellent skin compatibility, adhesion, and scratch resistance, having a good feel, and being easy to peel. A composition for forming a coating film, for forming a coating film composed of fibers directly on the skin by an electrostatic spray, the composition comprising the following Components (a), (b), (c), and (d): (a) a polymer having a coating film forming ability (b) one or more volatile substances selected from the group consisting of an alcohol and a ketone (c) a plasticizer (d) a feel modifier other than Component (c).

Drug delivery systems and wearable articles including the drug delivery systems are provided. The drug delivery systems may include a substrate coated with at least one polymer and at least one active compound. The substrate is operable to include yarns, yarn precursors, threads, filaments, fibers, and/or other suitable substrates. Methods for manufacturing drug delivery systems are also provided. The methods are operable to include disposing a solution including a monomer and an active compound on the substrate. The methods are also operable to include exposing the solution and the substrate to UV light to initiate polymerization of the solution.