Patent classifications
A61K8/63
METHOD FOR PRODUCING LIQUID COMPOSITION FOR ORAL CAVITY AND LIQUID COMPOSITION FOR ORAL CAVITY
The present invention relates to a method for producing a liquid composition for oral cavity in which β-glycyrrhetinic acid is stably dispersed or dissolved to exhibit an increased transparency and which also can ensure a sufficient amount of β-glycyrrhetinic acid adsorbed on gingiva, even if the amount of a cationic surfactant or an anionic surfactant is restricted; and such a liquid composition for oral cavity. Specifically, the present invention relates to a method for producing a liquid composition for oral cavity, comprising the following step 1 to step 4: (Step 1) a step of blending water (F) with an organic acid and a salt thereof (E) to adjust the pH of a resultant mixture to 5 or more and 6.8 or less, (Step 2) a step of blending 0.02% by mass or more and 0.1% by mass or less of cetylpyridinium chloride (B) into the mixture, (Step 3) a step of blending 0.02% by mass or more and 0.1% by mass or less of β-glycyrrhetinic acid (A) and 2% by mass or more and 10% by mass or less of propylene glycol (C) into the mixture, and (Step 4) a step of blending 0.45% by mass or more and 1.1% by mass or less of polyoxyethylene hydrogenated castor oil (D) into the mixture, wherein the component (A) and the component (B) are blended at a specific mass ratio, and these steps are carried out in a specific order.
WATER-BASED COSMETIC
A water-based cosmetic including:
agar having a weight average molecular weight of 10,000 to 60,000 (component (A));
xanthan gum (component (B)); and
a water-soluble polymer excluding the component (A) or (B) (component (C)).
WATER-BASED COSMETIC
A water-based cosmetic including:
agar having a weight average molecular weight of 10,000 to 60,000 (component (A));
xanthan gum (component (B)); and
a water-soluble polymer excluding the component (A) or (B) (component (C)).
COMPOSITION FOR INHIBITING HAIR GRAYING, AND USE THEREOF
Provided is a composition for inhibiting hair graying, having an excellent effect of preventing the occurrence of gray hair, and a use thereof. A composition for inhibiting hair graying, of the presently claimed subject matter, activates the Wnt and β-catenin signaling pathway to promote melanin synthesis in hair, thereby having remarkably excellent hair graying (canities) inhibition, prevention, improvement, alleviation, delaying, or treatment effects.
COMPOSITION FOR INHIBITING HAIR GRAYING, AND USE THEREOF
Provided is a composition for inhibiting hair graying, having an excellent effect of preventing the occurrence of gray hair, and a use thereof. A composition for inhibiting hair graying, of the presently claimed subject matter, activates the Wnt and β-catenin signaling pathway to promote melanin synthesis in hair, thereby having remarkably excellent hair graying (canities) inhibition, prevention, improvement, alleviation, delaying, or treatment effects.
HAIR COMPOSITION
Disclosed is an oral or topical composition comprising a nuclear factor erythroid-2 related factor 2 agonist and a liver X receptor agonist, wherein the amounts of each of the nuclear factor erythroid-2 related factor 2 agonist and the liver X receptor agonist produce a synergistic benefit of hair fibre growth, wherein the oral or topical composition comprises ≦9, preferably ≦8% w/w β-sitosterol, wherein when the oral or topical composition comprises a catechin, the oral or topical composition comprises 0.001 to 90, preferably 0.005 to 70, most preferably 0.01 to 50% w/w catechins, wherein the oral or topical composition excludes pregnenolone, 4, 5-dihydrofuranodiene-6-one, epoxy santamarin, hydroquinone, longistyline, monacolin K, protoanemonin, N-(2,2,2-tri-fluoro-ethyl)-N-[4-(2,2,2-tri-fluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide, dihydronepetalactone, iridomyrmecin, and dihydroactinidiolide, wherein when the oral or topical composition comprises guggelsterone and epigallocatechin gallate, the oral or topical composition excludes a guggelsterone to epigallocatechin gallate weight ratio of 1 to 28, and wherein when the oral or topical composition comprises sodium dilauramide glutamide lysine, the oral or topical composition excludes 0.3% w/w sodium dilauramide glutamide lysine.
HAIR COMPOSITION
Disclosed is an oral or topical composition comprising a nuclear factor erythroid-2 related factor 2 agonist and a liver X receptor agonist, wherein the amounts of each of the nuclear factor erythroid-2 related factor 2 agonist and the liver X receptor agonist produce a synergistic benefit of hair fibre growth, wherein the oral or topical composition comprises ≦9, preferably ≦8% w/w β-sitosterol, wherein when the oral or topical composition comprises a catechin, the oral or topical composition comprises 0.001 to 90, preferably 0.005 to 70, most preferably 0.01 to 50% w/w catechins, wherein the oral or topical composition excludes pregnenolone, 4, 5-dihydrofuranodiene-6-one, epoxy santamarin, hydroquinone, longistyline, monacolin K, protoanemonin, N-(2,2,2-tri-fluoro-ethyl)-N-[4-(2,2,2-tri-fluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide, dihydronepetalactone, iridomyrmecin, and dihydroactinidiolide, wherein when the oral or topical composition comprises guggelsterone and epigallocatechin gallate, the oral or topical composition excludes a guggelsterone to epigallocatechin gallate weight ratio of 1 to 28, and wherein when the oral or topical composition comprises sodium dilauramide glutamide lysine, the oral or topical composition excludes 0.3% w/w sodium dilauramide glutamide lysine.
Use of magnolia figo extract in the manufacture of compound for reducing epidermal desquamation and promoting wound healing
A use of Magnolia figo extract in the manufacture of a compound for reducing epidermal desquamation and promoting wound healing.
A HYDROALCOHOLIC GEL AND A METHOD OF MANUFACTURING SAID GEL
The present invention relates to a hydroalcoholic gel comprising at least 70 weight % alcohol, between 5 and 10 weight % of an oil composition, between 0.15 and 6 weight % of a gelling agent and between than 0.01 and 0.1 weight % of a pH adjusting agent, and wherein the gelling agent consist of between 0.05 and 2.0 weight % of a carbomer and between 0.1 and 4.5 weight % of a cellulose polymer composition. Said hydroalcoholic gel is unique in that it destroys microorganisms and virus, moisturizes the skin, does not leave an oily residue and a tacky feel on the skin, and adheres firmly to the skin (even after washing) thereby providing a long-term disinfecting effect.
A HYDROALCOHOLIC GEL AND A METHOD OF MANUFACTURING SAID GEL
The present invention relates to a hydroalcoholic gel comprising at least 70 weight % alcohol, between 5 and 10 weight % of an oil composition, between 0.15 and 6 weight % of a gelling agent and between than 0.01 and 0.1 weight % of a pH adjusting agent, and wherein the gelling agent consist of between 0.05 and 2.0 weight % of a carbomer and between 0.1 and 4.5 weight % of a cellulose polymer composition. Said hydroalcoholic gel is unique in that it destroys microorganisms and virus, moisturizes the skin, does not leave an oily residue and a tacky feel on the skin, and adheres firmly to the skin (even after washing) thereby providing a long-term disinfecting effect.