The present disclosure provides compositions as topical creams for treating vaginal atrophy, methods of making these compositions, and methods of using these compositions to treat vaginal atrophy.

The present disclosure provides compositions as topical creams for treating vaginal atrophy, methods of making these compositions, and methods of using these compositions to treat vaginal atrophy.

The present disclosure provides a liposomal topical formulation comprising dutasteride having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

The present invention is directed to a composition for the delivery of bioactive agents into hair follicles. The composition is prepared as an oil-in-water emulsion, and comprises one or more lipophilic bioactive agents, one or more oil solvents, one or more emulsifiers and water, wherein said bioactive agents are substantially dissolved in the internal oil phase of said emulsion, and wherein the mean droplet size of said emulsion is in the range of about 200 to about 1000 nm. The invention also encompasses methods for delivering said compositions into the hair follicle, and for treating diseases and disorders thereof.

The present invention is directed to a composition for the delivery of bioactive agents into hair follicles. The composition is prepared as an oil-in-water emulsion, and comprises one or more lipophilic bioactive agents, one or more oil solvents, one or more emulsifiers and water, wherein said bioactive agents are substantially dissolved in the internal oil phase of said emulsion, and wherein the mean droplet size of said emulsion is in the range of about 200 to about 1000 nm. The invention also encompasses methods for delivering said compositions into the hair follicle, and for treating diseases and disorders thereof.

Provided are a reelin and/or VEGF-C production and/or activation promoter including a compound represented by Chemical Formula 1 or a salt thereof as an active ingredient, and a skin external composition including the same.

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(In Chemical Formula 1, each substituent is as defined in the specification.)

Personal care compositions and, particularly, personal care compositions for alleviating dandruff are disclosed herein. The personal care compositions may include from about 0.1 to about 5 wt. % of an anti-dandruff agent comprising dipotassium glycyrrhizate; from about 6 to about 30 wt. % of a surfactant system; from about 0.1 to about 5 wt. % of a cationic polymer, wherein the personal care composition has a pH of about 2.5 to about 5 and all weight percentages are based on the total weight of the personal care composition. The surfactant system typically comprises from about 5 to about 20 wt. % of an anionic surfactant, from about 0.5 to about 7 wt. % of an amphoteric surfactant, and optionally, from about 0.5 to about 7 wt. % of a non-ionic surfactant.

Personal care compositions and, particularly, personal care compositions for alleviating dandruff are disclosed herein. The personal care compositions may include from about 0.1 to about 5 wt. % of an anti-dandruff agent comprising dipotassium glycyrrhizate; from about 6 to about 30 wt. % of a surfactant system; from about 0.1 to about 5 wt. % of a cationic polymer, wherein the personal care composition has a pH of about 2.5 to about 5 and all weight percentages are based on the total weight of the personal care composition. The surfactant system typically comprises from about 5 to about 20 wt. % of an anionic surfactant, from about 0.5 to about 7 wt. % of an amphoteric surfactant, and optionally, from about 0.5 to about 7 wt. % of a non-ionic surfactant.

The present disclosure relates to bleomycin for use in the treatment and/or prevention of hair loss and to a composition comprising bleomycin for use in the treatment and/or prevention of hair loss. A non-therapeutic method for promoting hair generation and/or hair growth is also disclosed, the method comprising administering or applying bleomycin or a composition comprising bleomycin to an area on the subject where the promotion of hair generation and/or hair growth is desired. Further disclosed is a non-therapeutic method for darkening hair, the method comprising administering or applying bleomycin or a composition comprising bleomycin to an area on the subject where darkening of hair is desired.

An application of a series of compounds in controlling or killing mites. It has been found by comparison that the compounds, when compared with a control group, can reduce the survival time of mites; in particular, taraxerol, diosmetin, and taraxasteryl acetate can significantly shorten the survival time of mites, and can be used for miticide and mite control products (such as drugs, cosmetic products, daily products and so on).