A water-soluble glass bolus article in a form suitable for oral administration to a ruminant animal, the article comprising carboxylate glass and an organic active agent. Metal carboxylates such as acetates, propanoates and butanoates can be melted to a glass and have a lower melting temperature than phosphate-based glass materials, allowing thermally sensitive active agents to be formulated into a glass bolus article. The carboxylate glass is formed from one or more metal carboxylates having a melting point of less than 300? C. in which the anion is selected from one or more acetates, propanoates, or a mixture of carboxylate anions. The metal may be selected from sodium, potassium, calcium and zinc.

A water soluble or water dispersible rumen bolus article suitable for oral administration to a reticulo rumen of a ruminant animal is described. The rumen bolus article comprises a water soluble or water dispersible matrix and seaweed or a seaweed extract enriched in at least one bioactive agent, wherein the rumen bolus article when administered to the reticulo rumen of the ruminant animal is configured to release the seaweed or seaweed extract over a sustained period of time. The seaweed extract is enriched in one or more bioactive agents selected from a vitamin, a mineral, an essential amino acid, an antioxidants, fibre, and a lipid. Bioactive agent generally constitutes at least 5 or 10% of the seaweed extract by weight. The seaweed extract is a lyophilised seaweed extract.

The present disclosure provides consumable compositions comprising a haloalkane and a medium chain triglyceride, methods of preparing the consumable composition, and methods of administering the consumable compositions.

The present disclosure provides consumable compositions comprising a haloalkane and a medium chain triglyceride, methods of preparing the consumable composition, and methods of administering the consumable compositions.

The present disclosure provides consumable compositions comprising a haloalkane and a medium chain triglyceride, methods of preparing the consumable composition, and methods of administering the consumable compositions.

Systems and methods provide sugar alcohol to heat stressed ruminants to improve performance. During periods of high temperature or humidity, heat stressed ruminants may exhibit decreased dry matter intake, and in response, an effective amount of sugar alcohol such as sorbitol may be provided in the ruminant diet to cause performance to increase, which may include increased milk yield, improved feed efficiency or both compared to heat stressed dairy cattle without sugar alcohol in the diet.

The invention provides a dosage form and a bolus configured for administration to an animal, wherein said dosage form and said bolus is configured to release a methane inhibitor to the animal over a period of time. Preferably the methane inhibitor is a haloform. Also provided is the use of the bolus of the invention to reduce methane production in a ruminant animal. Also provided is the method of manufacturing a bolus of the invention.

The invention provides a delayed release dosage form and a bolus configured for administration to an animal, wherein the dosage form and the bolus is configured to release a hydrophobic substance to the animal over a period of time. Preferably the hydrophobic substance is a haloform. Also provided is the use of the delayed release dosage form or bolus of the invention to reduce methane production in a ruminant animal. Also provided is the method of manufacturing a bolus of the invention.

This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.

This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.