The invention comprises a ready to use film dosage form comprising microemulsion of an Active Pharmaceutical Ingredient embedded or immobilized in a thin polymeric matrix as a double microemulsion and a process of making the same. The microemulsion in the film dosage form of this invention is capable of being absorbed through mucosal route. The process of making the film dosage of this invention comprises steps of forming a film forming dispersion containing film forming polymers, excipients and microemulsion of active pharmaceutical ingredient, casting the same in the form of a film and drying the cast of the film being carried out by means of drying conditions that suit to retain stability of the active pharmaceutical ingredient being selected such that drying of the film is achieved retaining the moisture trapped in the microemulsion embedded in the polymeric film.

The invention comprises a ready to use film dosage form comprising microemulsion of an Active Pharmaceutical Ingredient embedded or immobilized in a thin polymeric matrix as a double microemulsion and a process of making the same. The microemulsion in the film dosage form of this invention is capable of being absorbed through mucosal route. The process of making the film dosage of this invention comprises steps of forming a film forming dispersion containing film forming polymers, excipients and microemulsion of active pharmaceutical ingredient, casting the same in the form of a film and drying the cast of the film being carried out by means of drying conditions that suit to retain stability of the active pharmaceutical ingredient being selected such that drying of the film is achieved retaining the moisture trapped in the microemulsion embedded in the polymeric film.

Emulsions and layered compositions for improving thermal resistance of a substrate, such as a therapeutic or prophylactic medicinal substrate, are provided. Also provided are methods and kits for making the emulsions and layered compositions of the invention. The layered compositions and emulsions can be used to extend the shelf life of a product.

Emulsions and layered compositions for improving thermal resistance of a substrate, such as a therapeutic or prophylactic medicinal substrate, are provided. Also provided are methods and kits for making the emulsions and layered compositions of the invention. The layered compositions and emulsions can be used to extend the shelf life of a product.

Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.

An emulsion of water and oil comprising a solution of silicic acid and one or more stabilizing compounds in water, and one or more block copolymers as emulsifiers. Aside from water-in-oil and oil-in-water emulsions, the invention also offers co-emulsions of water with silicic acid in oil in water, water in oil in silicic acid with water, and oil in water with silicic acid in oil. Aside from silicic acid, the emulsion or co-emulsion preferably comprises one or more other, oil-soluble and/or water-soluble, active ingredients. The stable emulsions with silicic acid according to the invention can be favorably used for medical or cosmetic purposes, as dietary supplements, liquid fertilizers, crop protection agents, biocides, biostimulants, plant nutrients, soil improvers, catalyzers, antioxidants, or household products.

An emulsion of water and oil comprising a solution of silicic acid and one or more stabilizing compounds in water, and one or more block copolymers as emulsifiers. Aside from water-in-oil and oil-in-water emulsions, the invention also offers co-emulsions of water with silicic acid in oil in water, water in oil in silicic acid with water, and oil in water with silicic acid in oil. Aside from silicic acid, the emulsion or co-emulsion preferably comprises one or more other, oil-soluble and/or water-soluble, active ingredients. The stable emulsions with silicic acid according to the invention can be favorably used for medical or cosmetic purposes, as dietary supplements, liquid fertilizers, crop protection agents, biocides, biostimulants, plant nutrients, soil improvers, catalyzers, antioxidants, or household products.

The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.

The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.

The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins.