A pouched product adapted for release of a releasable component therefrom is provided herein. The pouched product can include a water-permeable fabric pouch formed so as to define a cavity therein, and a composition contained within the cavity of the water-permeable fabric pouch, the composition including one or more releasable components that are released from the composition under mouth conditions and that are capable of movement through the water-permeable fabric pouch. The composition includes nicotine and at least one particulate non-tobacco material. The pouched product also includes at least one capsule contained within the cavity of the water-permeable fabric pouch, the capsule having a capsule wall surrounding an inner payload comprising at least one botanical.

A pouched product adapted for release of a releasable component therefrom is provided herein. The pouched product can include a water-permeable fabric pouch formed so as to define a cavity therein, and a composition contained within the cavity of the water-permeable fabric pouch, the composition including one or more releasable components that are released from the composition under mouth conditions and that are capable of movement through the water-permeable fabric pouch. The composition includes nicotine and at least one particulate non-tobacco material. The pouched product also includes at least one capsule contained within the cavity of the water-permeable fabric pouch, the capsule having a capsule wall surrounding an inner payload comprising at least one botanical.

The present disclosure relates to methods of formulating therapeutic oil blends comprising one or more terpenes, wherein the methods may result in blends exhibiting increased stability and bioavailability. The methods may be used to produce compositions for dermal or transdermal application useful in the treatment of, e.g., pain. Disclosed methods may also result in improved homogeneity and non-crystallization of the formulated products.

The present disclosure relates to methods of formulating therapeutic oil blends comprising one or more terpenes, wherein the methods may result in blends exhibiting increased stability and bioavailability. The methods may be used to produce compositions for dermal or transdermal application useful in the treatment of, e.g., pain. Disclosed methods may also result in improved homogeneity and non-crystallization of the formulated products.

A topical composition for nociceptive and neuropathic pain relief comprising one or more of menthol, camphor, methyl sulfonyl methane, lidocaine, arnica montana, harpagophytum tincture, Emu oil, maqui powder, piper nigrum, turmeric oil and in some embodiments acetyl or methyl salicylate or capsaicin with cannabis sativa.

A topical composition for nociceptive and neuropathic pain relief comprising one or more of menthol, camphor, methyl sulfonyl methane, lidocaine, arnica montana, harpagophytum tincture, Emu oil, maqui powder, piper nigrum, turmeric oil and in some embodiments acetyl or methyl salicylate or capsaicin with cannabis sativa.

A topical composition for nociceptive and neuropathic pain relief comprising one or more of menthol, camphor, methyl sulfonyl methane, lidocaine, arnica montana, harpagophytum tincture, Emu oil, maqui powder, piper nigrum, turmeric oil and in some embodiments acetyl or methyl salicylate or capsaicin with cannabis sativa.

Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.

Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.

Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.