The disclosed wound-healing formulation adds ingredients from the group consisting of camphor, menthol and eucalyptus to known silver sulfadiazine-based formulations, or to known silver sulfadiazine-and-urogastrone-based formulations, preferably for the topical treatment of skin wounds such as cuts, burns, surgical wounds, etc. Preferred embodiments are in cream form. The disclosed formulation shows unexpected and startling improvement in wound healing rates over expected healing rates using the known silver sulfadiazine-based or silver sulfadiazine-and-urogastrone-based formulations alone.

The disclosed wound-healing formulation adds ingredients from the group consisting of camphor, menthol and eucalyptus to known silver sulfadiazine-based formulations, or to known silver sulfadiazine-and-urogastrone-based formulations, preferably for the topical treatment of skin wounds such as cuts, burns, surgical wounds, etc. Preferred embodiments are in cream form. The disclosed formulation shows unexpected and startling improvement in wound healing rates over expected healing rates using the known silver sulfadiazine-based or silver sulfadiazine-and-urogastrone-based formulations alone.

A method for preventing or treating metabolic diseases includes administering a composition including a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof to a subject in need thereof. Thereby, it is possible to inhibit increases in body weight and liver fat weight due to a high-calorie diet, and decrease an accumulation of fat in the liver tissue, as well as modulate gene expression related to fat metabolism, and ultimately exhibit excellent preventive and therapeutic effects on metabolic diseases.

A method for preventing or treating metabolic diseases includes administering a composition including a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof to a subject in need thereof. Thereby, it is possible to inhibit increases in body weight and liver fat weight due to a high-calorie diet, and decrease an accumulation of fat in the liver tissue, as well as modulate gene expression related to fat metabolism, and ultimately exhibit excellent preventive and therapeutic effects on metabolic diseases.

A topical ointment composition for nasal and sinus decongestion includes camphor, eucalyptus oil, menthol, garlic paste, sodium bicarbonate, isopropyl alcohol, water, and petrolatum. The topical ointment composition is applied to nasal vestibules of a user to reduce nasal and sinus congestion.

A topical ointment composition for nasal and sinus decongestion includes camphor, eucalyptus oil, menthol, garlic paste, sodium bicarbonate, isopropyl alcohol, water, and petrolatum. The topical ointment composition is applied to nasal vestibules of a user to reduce nasal and sinus congestion.

Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, or reduce biofilms, or to inhibit or substantially prevent biofilm formation. In certain aspects, the present invention relates to compounds, compositions, and methods comprising polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms.

A skin-sensitizing formulation is provided in an edible, softgel pill. A person engaged in a sexual activity bites down on the pill, thereby effectuating the oral release of the skin-sensitizing formulation. This allows the skin-sensitizing formulation to be spread to a sexual partner, on any part of the skin or sexual region of the body preferably through oral contact with the partner. The skin-sensitizing substance is spread to the partner directly on the skin or through oral contact or beneath a condom worn by the partner. The skin-sensitizing formulation may include an essential mint oil, analog or derivative, and may further includes an enhancer, rubefacient, counterirritant, anesthetic, k-opioid receptor activator, or TRPM8 activator. Various inactive ingredients are also disclosed.

A skin-sensitizing formulation is provided in an edible, softgel pill. A person engaged in a sexual activity bites down on the pill, thereby effectuating the oral release of the skin-sensitizing formulation. This allows the skin-sensitizing formulation to be spread to a sexual partner, on any part of the skin or sexual region of the body preferably through oral contact with the partner. The skin-sensitizing substance is spread to the partner directly on the skin or through oral contact or beneath a condom worn by the partner. The skin-sensitizing formulation may include an essential mint oil, analog or derivative, and may further includes an enhancer, rubefacient, counterirritant, anesthetic, k-opioid receptor activator, or TRPM8 activator. Various inactive ingredients are also disclosed.

A smokeless tobacco product or medicinal nicotine product includes nicotine and camphor dissolved in a non-flavored oily carrier. Preferably, the camphor is present in a concentration ranging from about 600 ppm to about 1300 ppm. Also disclosed are methods of making such products.