Methods for the use of prodrugs of itaconic acid and 1- and 4-methyl itaconic acid for inducing hair growth and treating an inflammatory, or immune activation (adaptive or innate), skin condition or other condition associated with hair loss are disclosed.

Methods for the use of prodrugs of itaconic acid and 1- and 4-methyl itaconic acid for inducing hair growth and treating an inflammatory, or immune activation (adaptive or innate), skin condition or other condition associated with hair loss are disclosed.

Methods for the use of prodrugs of itaconic acid and 1- and 4-methyl itaconic acid for inducing hair growth and treating an inflammatory, or immune activation (adaptive or innate), skin condition or other condition associated with hair loss are disclosed.

Provided is a novel compound and a use thereof. A novel compound according to the presently claimed subject matter induces the activation of MKP-1 protein to block the cellular signaling pathway proceeding in the order of p38/CK2α/NF-κB, thereby very effectively inhibiting an inflammatory response occurring in a respiratory disease. Therefore, a respiratory disease can be prevented, alleviated, or treated by orally administering the novel compound according to the presently claimed subject matter.

Provided is a novel compound and a use thereof. A novel compound according to the presently claimed subject matter induces the activation of MKP-1 protein to block the cellular signaling pathway proceeding in the order of p38/CK2α/NF-κB, thereby very effectively inhibiting an inflammatory response occurring in a respiratory disease. Therefore, a respiratory disease can be prevented, alleviated, or treated by orally administering the novel compound according to the presently claimed subject matter.

A cancer drug for use in the treatment of cancer in which caffeic acid phenethyl ester (CAPE) is encapsulated in poly [lactic-co-glycolic acid] (PLGA) to increase its solubility in aqueous media is provided. Angiopep-2 is used as a specific ligand to increase biological activity. In an embodiment of the invention, PLGA is preferably in the form of nanoparticles, thereby ensuring better solubility.

A cancer drug for use in the treatment of cancer in which caffeic acid phenethyl ester (CAPE) is encapsulated in poly [lactic-co-glycolic acid] (PLGA) to increase its solubility in aqueous media is provided. Angiopep-2 is used as a specific ligand to increase biological activity. In an embodiment of the invention, PLGA is preferably in the form of nanoparticles, thereby ensuring better solubility.

A natural antibacterial and antiviral biological composition is provided for use in hospitals and homes, in particular a composition that includes ricinoleic acid derived from the extraction of castor oil, diethanolamine and propolis, a method for obtaining the composition, and the use thereof. The invention can be used to control various pathogenic microorganisms, such as bacteria belonging to the Staphylococcus, Pseudomonas, Enterobacter and Bacillus genera; as well as hospital-environment fungi (filamentous and yeast-like) and phytopathogenic fungi (Colletrotichum fragariae). The product can be sprayed on biotic and abiotic surfaces, and non-woven fabric can subsequently be used to remove organic matter, including microorganisms. The product can also be used to disinfect medical, dental and hospital items by immersion followed by quick rinsing.

A natural antibacterial and antiviral biological composition is provided for use in hospitals and homes, in particular a composition that includes ricinoleic acid derived from the extraction of castor oil, diethanolamine and propolis, a method for obtaining the composition, and the use thereof. The invention can be used to control various pathogenic microorganisms, such as bacteria belonging to the Staphylococcus, Pseudomonas, Enterobacter and Bacillus genera; as well as hospital-environment fungi (filamentous and yeast-like) and phytopathogenic fungi (Colletrotichum fragariae). The product can be sprayed on biotic and abiotic surfaces, and non-woven fabric can subsequently be used to remove organic matter, including microorganisms. The product can also be used to disinfect medical, dental and hospital items by immersion followed by quick rinsing.

The present invention is directed to a personal composition comprising a) a strobilurin; b) salicylic acid wherein the ratio of a:b is from about 1:1 to about 100:1; wherein there is a synergistic anti-inflammatory/cellular stress activity.