Provided herein are pharmaceutical compositions and methods useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression.

Provided herein are pharmaceutical compositions and methods useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression.

The present disclosure relates to the treatment of cancer using a combination therapy comprising Compound 1 and/or tautomers thereof or a pharmaceutically acceptable salt or hydrate thereof, and a second therapy.

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The present disclosure relates to the treatment of cancer using a combination therapy comprising Compound 1 and/or tautomers thereof or a pharmaceutically acceptable salt or hydrate thereof, and a second therapy.

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The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

Disclosed is the use of foam compositions for the delivery of therapeutics to a body cavity, organ, or tissue of a patient in need thereof. Also disclosed are foam compositions, and devices for delivering the composition to a body cavity or the interior or exterior of an organ. Additionally, methods of treating cancer in the internal organs or the body cavity using the foam compositions are also disclosed.

Disclosed is the use of foam compositions for the delivery of therapeutics to a body cavity, organ, or tissue of a patient in need thereof. Also disclosed are foam compositions, and devices for delivering the composition to a body cavity or the interior or exterior of an organ. Additionally, methods of treating cancer in the internal organs or the body cavity using the foam compositions are also disclosed.

The present invention provides for a method to treat pancreatic cancer. In various embodiments the method provides for administering one or more MAPK one or more MAPK pathway inhibitors to the subject, wherein the subject has a mutation in one or more genes in the MAPK signaling pathway.