The invention concerns the field of container closure integrity (CCI) and the testing of CCI and relates to a device and a method for leakage testing of a connection between a rubber stopper and a corresponding drug container which can be used for storing drugs under sterile conditions and which is closed by said rubber stopper.

Methods and systems for detecting leakage in a permeability measurement system. The method includes connecting a plurality of flow lines to a first dimension of a core sample assembly, connecting one or more flow lines to a second dimension of the core sample assembly, placing the core sample assembly with the connections in a measurement cell such that the flow lines are accessible from outside of the measurement cell, connecting one or more gas sensors to one end of each of the flow lines, connecting an inlet of the measurement cell to a gas tank, setting fluid pressure inside the measurement cell to a predetermined value, and detecting a leakage in the core sample assembly by the one or more gas sensors coupled to the flow lines.

A method for a tightness test of a test object filled with a liquid, said test object having an internal pressure which is lower than atmospheric pressure, comprising the following steps: inserting the test object into a test chamber, evacuating the test chamber to a pressure which is lower than the internal pressure inside the test object, drawing off the test chamber residual gas components together with gas components desorbing from a wall of the test chamber and parts of the liquid escaping from the test object through a leak in the latter without any carrier gas being fed to the test chamber from outside, transporting the drawn-off residual gas components together with the parts of the liquid escaped from the test object to a detector, and detecting parts of the liquid escaped through a leak in the test object by means of a detector.

The invention concerns the field of container closure integrity (CCI) and the testing of CCI and relates to a device and a method for leakage testing of a connection between a rubber stopper and a corresponding drug container which can be used for storing drugs under sterile conditions and which is closed by said rubber stopper.

A vacuum leak detection system may comprise a test chamber unit having a test chamber gas inlet and a test chamber gas outlet, a gas detection unit having a gas detection gas inlet and a gas detection gas outlet, and a gas control unit connecting the test chamber gas inlet and the test chamber gas outlet to the gas detection gas inlet and the gas detection gas outlet, which is connected to the test chamber unit and to the gas detection unit, and which has separate gas line paths for optionally connecting the gas inlets and the gas outlets of the test chamber unit and the gas detection unit, wherein the gas control unit has a third gas inlet which is open towards the atmosphere and which can be connected to the test chamber gas inlet via a gas line path running through the gas control unit.

Described herein is an apparatus for detecting leakage of an emanated gas from an inorganic compound stored in a container. The apparatus includes an enclosure structured to conceal a closure secured to the container. A flow creation device is fluidically connected to the enclosure, the flow creation device is configured to create a flow of the emanated gas from the enclosure. Further, a gas monitoring unit is fluidically connected between the enclosure and the flow creation device. The gas monitoring unit is structured to receive at least a portion of the emanated gas from the enclosure and detect concentration of at least one constituent present in the emanated gas. The disclosure also includes a system incorporating a control unit for detecting leakage of an emanated gas from an inorganic compound stored in a container.

The invention relates to a method for detecting leakage of a hollow component, comprising the steps of sealing said hollow component (1, 31), creating a pressure difference P1 and P2 between said hollow component interior and an adjacent compartment/enclosure (2, 32), putting a tracer gas in one of the hollow component or said compartment/enclosure, waiting for an enriching time T and then carrying out a step of transferring, via a non-selective or selective restriction (6, 7; 49), the content of said hollow component or said compartment/enclosure (2; 32) into which tracer gas has not been put, in order to concentrate, in a volume downstream of said restriction (6, 7; 49), the tracer gas that said content may possibly contain, and then in looking for the presence of tracer gas in said volume. The invention also relates to an installation for implementing the method.

A leakage inspection device includes an inspection chamber in which an inspection object is disposed to be filled with a tracer gas, and a circulation passage which connects a suction port disposed in the inspection chamber and a blowout port disposed at a position away from the suction port in the inspection chamber with each other. The leakage inspection device includes a blower disposed in the circulation passage to circulate gas by sucking from the inspection chamber through the suction port and by blowing out from the blowout port. The leakage inspection device includes a detector configured to detect the tracer gas leaked from the inspection object and contained in the gas flowing through the circulation passage at a position separated by a predetermined distance or more from the blower toward the blowout port in the circulation passage.

The present invention provides a method for leak testing by which occurrence of fine leakage from a work as a test object can be determined without being affected by a released tracer gas that is also released from a non-defective work. The method for leak testing includes a series of steps including a gas bombing step wherein a work W as a test object is soaked in a pressurized tracer gas, a work setting step wherein the work subjected to the gas bombing is set in a hermetically sealed container 10, a vacuum suctioning step wherein the hermetically sealed container 10 is vacuum suctioned by a suction device 20 and a measuring step wherein tracer gas measurement data are obtained by measuring a vacuum suctioned tracer gas with a detector 30. Tracer gas measurement data for a non-defective work are preliminarily obtained by performing the series of steps for the non-defective work having same specifications as the work W as the test object. The tracer gas measurement data for the work W as the test object are compared with the tracer gas measurement data for the non-defective work in the measuring step, and thereby, occurrence of fine leakage from the work as the test object is determined.

The invention relates to a test chamber and to a method for operating a test chamber for conditioning air, in particular a temperature control chamber, a climate chamber or the like, the test chamber comprising a temperature-insulated test space, which can be sealed from an environment and serves to hold test material, and a temperature control device for controlling the temperature of the test space, the temperature control device being configured to establish a temperature in a temperature range of −50° C. to +180° C. within the test space, the temperature control device having a heating feature and a cooling feature with a cooling circuit with a refrigerant, a heat exchanger in the test space, a compressor, a condenser and an expansion member, the refrigerant being a hydrocarbon or a refrigerant mixture of hydrocarbons, the test chamber being provided with a machine room physically separated from the test space, the cooling circuit with the compressor being at least partially disposed in the machine room. The test chamber comprises a ventilation system having a detector with at least one gas sensor for detecting refrigerant in the test space, the ventilation system comprising a fan and an exhaust duct, the exhaust duct being connected to the test space in such a manner that the fan can transport air from the test space into the exhaust duct, the fan comprising a fan motor and a fan impeller, the fan motor being disposed in an air-tight enclosure, or the exhaust duct being connected to the test space and the machine room in such a manner that the one fan can transport air from the machine room and the test space into the exhaust duct.