The present application discloses a portable ultraviolet excited fluorescence intensity detector for carrying out quantitative fluorescence detection for a disposable hygiene product's raw materials and a method of using the same, comprising a housing, an ultraviolet emitting light path, a first receiving light path and a second receiving light path

A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(). The calibration factor g() is a function of the angle calculated at two or more of the plurality of locations. The angle is composed of a transversal angle .sub.t and an axial angle .sub.a.

A waveguide sensor system is provided. The system includes a light source and a waveguide formed from a light transmitting material. Light from the light source enters the waveguide at an input area and travels within the waveguide by total internal reflection to an analyte area and light to be analyzed travels within the waveguide from the analyte area by total internal reflection to an output area. An optical sensor is coupled to the output area and is configured to interact with the light to be analyzed. The system includes a plurality of pores located along the outer surface within the analyte area and formed in the light transmitting material of the waveguide, and the pores are configured to enhance light interaction with the analyte within the analyte area.

A system and method for detecting leakage oil with a high degree of accuracy while avoiding the complexity of the system and the influence of noise light comprise: ultraviolet light sources arranged to irradiate an oil-filled device from a plurality of different incidence angles, and are switched on and off at the respective incidence angles in sequence, and include a wavelength exciting oil; an imaging device to photograph the oil-filled device irradiated with ultraviolet light emitted from the ultraviolet light sources when the ultraviolet light sources are switched on; a recorder to record respective images photographed by the imaging device; and a display to display the respective images. The respective images are compared, a site where a light emitting position does not change always is judged as a leakage oil site, and a site emitting light or not emitting light occasionally is judged as a noise light site.

An optical fiber scanner is provided with an illumination optical fiber that guides light and emits the light from a distal end thereof; a plurality of piezoelectric elements that are secured on a side surface of the illumination optical fiber, that have polarizations in radial directions of the illumination optical fiber, and that vibrate the illumination optical fiber when an alternating voltage is applied in the polarization directions; and a vibration suppressing part that suppresses vibrations in the radial directions generated at a position of the illumination optical fiber away from the piezoelectric elements toward a base end.

Optical sensing techniques and devices based on detection of fluorescent emissions at different optical wavelengths by nonlinear optical absorption of different excitation beams at different excitation wavelengths that interact with fluorescently-labeled structures within the sample to cause nonlinear optical absorption of two or more photons at each excitation wavelength. The fluorescent light at different fluorescent emission wavelengths by nonlinear optical absorption of excitation light at a particular excitation wavelength is spectrally separated into different optical channel output beams along different optical channel optical paths at different designated fluorescent imaging wavelength bands and the fluorescent light at different fluorescent imaging wavelengths within each designated fluorescent imaging wavelength is detected. This two-stage spectral separation in obtaining fluorescent images at different fluorescent imaging wavelengths in different fluorescent imaging wavelength bands enables highly sensitive hyperspectral imaging based on two-photo or multi-photon nonlinear absorption.

The present invention concerns a device constituted by a planar optical antenna which allows to beam and collect light emitted from various light sources, including light-emitting devices (LEDs), fluorescent markers and single-photon sources. By considering the light source as a light receiver and using reciprocity, the device can also be used to improve the absorption of light by various receivers, including molecules. This device is in particular suitable for in-vitro diagnostics (IVD).

A microscopic observation apparatus that irradiates an observation target with excitation light to observe fluorescence generated from the observation target, the microscopic observation apparatus includes a light source that irradiates the observation target with excitation light; a first optical system that light-controls a plurality of light rays including fluorescence generated from the observation target by radiating the excitation light and part of the excitation light; a filter that reduces an intensity of light in a wavelength band of the excitation light among the plurality of light rays light-controlled by the first optical system; and a plurality of photoelectric conversion elements that converts a plurality of light rays that has passed through the filter into electricity.

A method of imaging a sample comprises serially illuminating the sample by a plurality of light beams, each having a different central wavelength. The method also comprises: serially acquiring from the sample image data by an imager, wherein the image data represent optical signals received from the sample responsively to the plurality of light beams. The method also comprises shifting a field-of-view of the sample relative to the imager, repeating the serial illumination and the image data acquisitions for the shifted field-of-view, and generating a spectral image of the sample using image data acquired by the imager at a plurality of field-of-views for each of the plurality of light beams.

Discloses are a microscopic imaging system and a microscopic imaging method for sample angle recognition. Firstly, a polarization rotation device introduced in an optical path of an excitation light can polarize and modulate the excitation light so as to make a polarization-modulated excitation light to rotate in a preset angle range; secondly, the polarization-modulated excitation light can be splitted into two parts via a beam splitting device, one for sample imaging, and the other for detection of polarization; and finally, a plurality of model characteristic curves can be obtained by a polarization detection device, each of the model characteristic curves corresponding to one angle, thus determining an angle information about an object to be analyzed in the sample.