Patent classifications
A61K35/18
METHOD FOR PRODUCING A BLOOD PRODUCT
An object of the invention is to provide a means for accomplishing inactivation of a pathogen in a blood sample containing red blood cells and platelets together, as well as sufficiently reducing the hemolysis rate of the red blood cell product finally obtained.
The means is to irradiate ultraviolet ray to a blood sample containing red blood cells and platelets in the presence of a hemolysis inhibitor and a surfactant having an HLB value of 13 or greater and having the number of oxyethylene groups of a hydrophilic portion in the molecular structure of 20 or greater when producing a blood product containing red blood cells and platelets.
METHOD FOR PRODUCING A BLOOD PRODUCT
An object of the invention is to provide a means for accomplishing inactivation of a pathogen in a blood sample containing red blood cells and platelets together, as well as sufficiently reducing the hemolysis rate of the red blood cell product finally obtained.
The means is to irradiate ultraviolet ray to a blood sample containing red blood cells and platelets in the presence of a hemolysis inhibitor and a surfactant having an HLB value of 13 or greater and having the number of oxyethylene groups of a hydrophilic portion in the molecular structure of 20 or greater when producing a blood product containing red blood cells and platelets.
METHOD FOR PRODUCING A BLOOD PRODUCT
An object of the invention is to provide a means for accomplishing inactivation of a pathogen in a blood sample containing red blood cells and platelets together, as well as sufficiently reducing the hemolysis rate of the red blood cell product finally obtained.
The means is to irradiate ultraviolet ray to a blood sample containing red blood cells and platelets in the presence of a hemolysis inhibitor and a surfactant having an HLB value of 13 or greater and having the number of oxyethylene groups of a hydrophilic portion in the molecular structure of 20 or greater when producing a blood product containing red blood cells and platelets.
Gene therapy methods
The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
Gene therapy methods
The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
PLATELET RICH PLASMA FORMULATIONS AND USE THEREOF
Compositions for platelet rich plasma (PRP) are provided. Generally, these compositions comprise a higher concentration of platelets than whole blood. Concentrations of lymphocytes, monocytes, and neutrophils may be different from concentrations found in whole blood. These compositions may have depressed concentrations of red blood cells and hemoglobin. In some variations, the compositions may be useful to treat damaged connective tissue, particularly spinal disc, and/or to slow or stop cardiac apoptosis after a heart attack.
PLATELET RICH PLASMA FORMULATIONS AND USE THEREOF
Compositions for platelet rich plasma (PRP) are provided. Generally, these compositions comprise a higher concentration of platelets than whole blood. Concentrations of lymphocytes, monocytes, and neutrophils may be different from concentrations found in whole blood. These compositions may have depressed concentrations of red blood cells and hemoglobin. In some variations, the compositions may be useful to treat damaged connective tissue, particularly spinal disc, and/or to slow or stop cardiac apoptosis after a heart attack.
PLATELET RICH PLASMA FORMULATIONS AND USE THEREOF
Compositions for platelet rich plasma (PRP) are provided. Generally, these compositions comprise a higher concentration of platelets than whole blood. Concentrations of lymphocytes, monocytes, and neutrophils may be different from concentrations found in whole blood. These compositions may have depressed concentrations of red blood cells and hemoglobin. In some variations, the compositions may be useful to treat damaged connective tissue, particularly spinal disc, and/or to slow or stop cardiac apoptosis after a heart attack.
Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell composition preparations for use in tissue regeneration and bone regeneration and pain reduction.
Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell composition preparations for use in tissue regeneration and bone regeneration and pain reduction.