The present disclosure describes pharmaceutical compositions and methods for reducing duration, intensity, and/or bothersomeness of common colds in humans and for reducing severity or duration of common cold symptoms such as nasal congestion, runny nose, watery eyes, dry/scratchy throat and sneezing in humans exhibiting such symptoms. The compositions herein comprise extracts of at least one of Luffa Operculata (L. operculata), S. officinale (V. sabadilla), and Galphimia Glauca (G. glauca) in a pharmaceutically acceptable carrier, and in various embodiments, comprise a mixture of all three Luffa Operculata (L. operculata) 10% extract MT, S. officinale (V. sabadilla) 3 extract, and Galphimia Glauca (G. glauca) 10% extract MT in a pharmaceutically acceptable carrier.

There are presented topical formulations and methods of applying these formulations in therapeutically effective amounts directly to areas of the human skin to remediate and to counter effects that are commonly regarded as aging. The formulations address the effects on the skin of UV light, High Energy Visible (HEV) light, blue light, and Urban Dust as well as remediating fine lines and age-related localized melanin concentrations (age spots), improving the uniformity of skin tone (reduction in skin redness) and enhancing the brightness of the skin to provide a more youthful appearance. Skin treated with the formulations also exhibit a reduction in the depth and prominence of wrinkles, a marked reduction in harmful reactive oxygen species in the treated skin, and a reduction in lipid peroxidation caused by Urban Dust.

There are presented topical formulations and methods of applying these formulations in therapeutically effective amounts directly to areas of the human skin to remediate and to counter effects that are commonly regarded as aging. The formulations address the effects on the skin of UV light, High Energy Visible (HEV) light, blue light, and Urban Dust as well as remediating fine lines and age-related localized melanin concentrations (age spots), improving the uniformity of skin tone (reduction in skin redness) and enhancing the brightness of the skin to provide a more youthful appearance. Skin treated with the formulations also exhibit a reduction in the depth and prominence of wrinkles, a marked reduction in harmful reactive oxygen species in the treated skin, and a reduction in lipid peroxidation caused by Urban Dust.

The present general inventive concept provides an all-natural pain relief topical ointment composition that is formed from natural ingredients that provides pain relief and other therapeutic benefits for various ailments including arthritis.

The present general inventive concept provides an all-natural pain relief topical ointment composition that is formed from natural ingredients that provides pain relief and other therapeutic benefits for various ailments including arthritis.

Skin care compositions, methods, and kits are provided. In some embodiments, the skin care compositions include one or more oils that include ximenynic acid, and one or more oils that include linolenic acid, and/or one or more oils that include linoleic acid. In certain embodiments, methods of using the aforementioned skin care formulations are provided for the treatment of acne, psoriasis, eczema, or dermatitis.

Skin care compositions, methods, and kits are provided. In some embodiments, the skin care compositions include one or more oils that include ximenynic acid, and one or more oils that include linolenic acid, and/or one or more oils that include linoleic acid. In certain embodiments, methods of using the aforementioned skin care formulations are provided for the treatment of acne, psoriasis, eczema, or dermatitis.

The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

The present disclosure is directed to a composition and method of enhancing skin health and appearance, as well as treating compromised skin, by applying onto the skin a composition containing a moisturizing/hydrating-effective amount of a mixture of at least: (a) an oil infusion of Calendula officinalis extract; (b) an oil infusion of Helichrysum italicum extract; (c) an oil infusion of Symphytum officinale extract; (d) an aqueous infusion of Viola tricolor extract; and (e) an aqueous infusion of at least one Mallow extract chosen from Malva sylvestris extract and Althea officinalis extract; and an emulsifying-effective amount of a dermatologically-acceptable emulsifier, wherein the composition is natural and free of a skin sensitizing-effective amount of an essential oil.