Disclosed are ruminant feed additive compositions comprising phytochemicals and/or vegetable extracts containing tannins essential oils, optionally saponins and optionally other phytochemicals, buffered with a plurality of acid-neutralizing calcium, magnesium, potassium, and/or sodium salts having pKa's effective at different ruminal and gastrointestinal pH ranges, where the combination of ingredients and their quantities are selected to provide compositions that improves dietary energy and nitrogen utilization efficiency and are effective to reduce greenhouse gas (GHG) emission from the animals. Also disclosed are methods of reducing GHG emissions from ruminants by feeding an effective amount of the composition in an animal feed.

A pharmaceutical or neutraceutical composition for preventing or treating of chronic inflammation and concomitant biofilms in the gastrointestinal tract (GI tract). The multidimensional clinically tested composition accelerates intestinal epithelium recovery and it destabilises Gram-negative bacteria in their habitat, but it also eliminates their LPS molecules, which are highly allergenic. The synergistic composition contains a pharmaceutically effective amount of at least L-glutamine with zinc and vitamine A for recovery of the epithelium cells of the gastrointestinal tract, at least enzymes selected from the group of polysaccharidases, proteases, lipases and/or antioxidants, for decomposing a bio film that is present in the gut, at least one chelator for inorganic components such as iron and at least one binder for organic components originating from the decomposition of the biofilm and/or bacteria.

A pharmaceutical or neutraceutical composition for preventing or treating of chronic inflammation and concomitant biofilms in the gastrointestinal tract (GI tract). The multidimensional clinically tested composition accelerates intestinal epithelium recovery and it destabilises Gram-negative bacteria in their habitat, but it also eliminates their LPS molecules, which are highly allergenic. The synergistic composition contains a pharmaceutically effective amount of at least L-glutamine with zinc and vitamine A for recovery of the epithelium cells of the gastrointestinal tract, at least enzymes selected from the group of polysaccharidases, proteases, lipases and/or antioxidants, for decomposing a bio film that is present in the gut, at least one chelator for inorganic components such as iron and at least one binder for organic components originating from the decomposition of the biofilm and/or bacteria.

A pharmaceutical composition comprising a tannin selected from 2-O-digalloyl-1,3,4,6-tetra-O-galloyl--D-glucose, 3-O-digalloyl-1,2,4,6-tetra-O-galloyl--D-glucose, 6-O-digalloyl-1,2,3,4-tetra-O-galloyl--D-glucose, 2,6-bis-O-digalloyl-1,3-di-O-galloyl--D-glucose, and 6-O-trigalloyl-1,2,3-tri-O-galloyl--D-glucose. The tannin may be derived from Quercus infectoria. The pharmaceutical composition is used in a method of treating cancer, particularly oral cancer.

A pharmaceutical composition comprising a tannin selected from 2-O-digalloyl-1,3,4,6-tetra-O-galloyl--D-glucose, 3-O-digalloyl-1,2,4,6-tetra-O-galloyl--D-glucose, 6-O-digalloyl-1,2,3,4-tetra-O-galloyl--D-glucose, 2,6-bis-O-digalloyl-1,3-di-O-galloyl--D-glucose, and 6-O-trigalloyl-1,2,3-tri-O-galloyl--D-glucose. The tannin may be derived from Quercus infectoria. The pharmaceutical composition is used in a method of treating cancer, particularly oral cancer.

A pharmaceutical composition comprising a tannin selected from 2-O-digalloyl-1,3,4,6-tetra-O-galloyl--D-glucose, 3-O-digalloyl-1,2,4,6-tetra-O-galloyl--D-glucose, 6-O-digalloyl-1,2,3,4-tetra-O-galloyl--D-glucose, 2,6-bis-O-digalloyl-1,3-di-O-galloyl--D-glucose, and 6-O-trigalloyl-1,2,3-tri-O-galloyl--D-glucose. The tannin may be derived from Quercus infectoria. The pharmaceutical composition is used in a method of treating cancer, particularly oral cancer.

A pharmaceutical composition comprising a tannin selected from 2-O-digalloyl-1,3,4,6-tetra-O-galloyl--D-glucose, 3-O-digalloyl-1,2,4,6-tetra-O-galloyl--D-glucose, 6-O-digalloyl-1,2,3,4-tetra-O-galloyl--D-glucose, 2,6-bis-O-digalloyl-1,3-di-O-galloyl--D-glucose, and 6-O-trigalloyl-1,2,3-tri-O-galloyl--D-glucose. The tannin may be derived from Quercus infectoria. The pharmaceutical composition is used in a method of treating cancer, particularly oral cancer.

Provided are methods for treating urogenital health conditions of a female subject. In some aspects, the methods comprise administering a composition comprising one or more oligosaccharides that are derived from one or more materials comprising at least one of galactomannan, -glucan, homo-xylan, glucuronoxylan, glucuronoarabinoxylan, arabinoxylan, arabinan, arabinogalactan, xyloglucan, microbial curdlan, glucomannan, pectic galactan, a moringa plant or part thereof, a Cucurbita species plant or part thereof, spent distillers' grains, gellan gum, xanthan gum, legumes, soy, pea, sugar cane, or any combination thereof. In some aspects the methods comprise administering one or more oligosaccharides each of which independently contains 3 to 30 subunits and wherein at least 5% of the subunits comprise a beta-1,3 glucose residue, a beta-1,4 glucose residue, or a combination thereof.

Provided are methods for treating urogenital health conditions of a female subject. In some aspects, the methods comprise administering a composition comprising one or more oligosaccharides that are derived from one or more materials comprising at least one of galactomannan, -glucan, homo-xylan, glucuronoxylan, glucuronoarabinoxylan, arabinoxylan, arabinan, arabinogalactan, xyloglucan, microbial curdlan, glucomannan, pectic galactan, a moringa plant or part thereof, a Cucurbita species plant or part thereof, spent distillers' grains, gellan gum, xanthan gum, legumes, soy, pea, sugar cane, or any combination thereof. In some aspects the methods comprise administering one or more oligosaccharides each of which independently contains 3 to 30 subunits and wherein at least 5% of the subunits comprise a beta-1,3 glucose residue, a beta-1,4 glucose residue, or a combination thereof.

A pharmaceutical composition comprising a tannin selected from 2-O-digalloyl-1,3,4,6-tetra-O-galloyl--D-glucose, 3-O-digalloyl-1,2,4,6-tetra-O-galloyl--D-glucose, 6-O-digalloyl-1,2,3,4-tetra-O-galloyl--D-glucose, 2,6-bis-O-digalloyl-1,3-di-O-galloyl--D-glucose, and 6-O-trigalloyl-1,2,3-tri-O-galloyl--D-glucose. The tannin may be derived from Quercus infectoria. The pharmaceutical composition is used in a method of treating cancer, particularly oral cancer.