The use is described of a chestnut tannin extract (Castanea sativa Mill.), as a non-phytotoxic acaricidal agent, alone or in a mixture with other active principles having an acaricidal activity.

A method of treating vaginal dryness by administering a vaginal care composition, which includes an effective amount of a vaginal care agent, to vaginal tissue of a user experiencing vaginal dryness. The vaginal care agent may be selected to specifically treat symptoms of vaginal dryness exhibited by the introitus and/or labia, based on the transcriptomic data of skin cells obtained therefrom. In some instances, the vaginal care composition may be applied to introitus and/or labia with a suitable implement configured for such use.

A method of treating vaginal dryness by administering a vaginal care composition, which includes an effective amount of a vaginal care agent, to vaginal tissue of a user experiencing vaginal dryness. The vaginal care agent may be selected to specifically treat symptoms of vaginal dryness exhibited by the introitus and/or labia, based on the transcriptomic data of skin cells obtained therefrom. In some instances, the vaginal care composition may be applied to introitus and/or labia with a suitable implement configured for such use.

An embodiment of the present invention provides a manufacturing method of an herbal medicinal tablet formulation for treating obesity which can be prescribed based on Sasang constitutional medicine, comprises manufacturing a concentrated and quantified ephedra powder agent so that an ephedrine content of ephedra, which differs from 0.5-2.5% depending on a producing district and collecting period, is 3.0-4.0%, determining a weight according to each constitution of Sasang constitutional medicine of the concentrated and quantified ephedra powder agent of which the ephedrine content is 3.0-4.0%, and manufacturing a side-effect-preventing powder agent for each constitution to prevent and suppress side effects according to constitution of Sasang constitutional medicine with respect to the weight of the ephedra powder agent, preparing the ephedra powder agent and the side-effect-preventing powder agent while varying a weight ratio therebetween in consideration of weight, obesity, constitution of Sasang constitutional medicine, and side effects while mixing the ephedra powder agent and the side-effect-preventing powder agent; tableting a mixture of the prepared ephedra powder agent and side-effect-preventing powder agent; coating the tableted ones after tableting; and after the coating, while sorting out defective ones from coated ones and packaging, displaying a label including information prepared according to weight, obesity, constitution of Sasang constitutional medicine, and side effects.

The present invention provides a functional food that utilizes health-promoting effects of charcoal, is readily ingested, has no adverse side effect, and has an effect of improving and repressing obesity. The functional food includes a charcoal composition having at least one of a bamboo charcoal, a Bincho charcoal, an activated bamboo charcoal and an activated Bincho charcoal, and both of the activated bamboo charcoal and the activated Bincho charcoal have a bulk density of 0.3 to 0.6 g/ml, an average particle size of 10 m or smaller, a BET specific surface area of 1000 to 1200 m.sup.2/g, and an iodine adsorption amount of 1000 to 1300 mg/g.

Managing and treating elevated OS biomarkers in mammals such as companion animals with at least one of the supplements alpha-lipoic acid, carnitine, co-enzyme Q-10, ginger, green tea, licorice, milk thistle, garlic, honey. resveratrol, soybeans, tomatoes, turmeric, vitamin D, vitamin E, or selenium. Other compounds are Zinc, Vitamin E, Vitamin C, Quercetin, L-glutamine and Robuvit. Diagnosing an oxidative stress (OS) in a mammal detects an OS biomarker, selectively isoprostane and other antioxidant biomarkers such as HODE, microRNAs, TAC, GSH, MDA, and TNF-alpha. The sample can be saliva.

Managing and treating elevated OS biomarkers in mammals such as companion animals with at least one of the supplements alpha-lipoic acid, carnitine, co-enzyme Q-10, ginger, green tea, licorice, milk thistle, garlic, honey. resveratrol, soybeans, tomatoes, turmeric, vitamin D, vitamin E, or selenium. Other compounds are Zinc, Vitamin E, Vitamin C, Quercetin, L-glutamine and Robuvit. Diagnosing an oxidative stress (OS) in a mammal detects an OS biomarker, selectively isoprostane and other antioxidant biomarkers such as HODE, microRNAs, TAC, GSH, MDA, and TNF-alpha. The sample can be saliva.

Managing and treating elevated OS biomarkers in mammals such as companion animals with at least one of the supplements alpha-lipoic acid, carnitine, co-enzyme Q-10, ginger, green tea, licorice, milk thistle, garlic, honey. resveratrol, soybeans, tomatoes, turmeric, vitamin D, vitamin E, or selenium. Other compounds are Zinc, Vitamin E, Vitamin C, Quercetin, L-glutamine and Robuvit. Diagnosing an oxidative stress (OS) in a mammal detects an OS biomarker, selectively isoprostane and other antioxidant biomarkers such as HODE, microRNAs, TAC, GSH, MDA, and TNF-alpha. The sample can be saliva.

Compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions) comprising tannic acids, particularly tannic acids which are D-amino acid oxidase inhibitor with superior potency, purity and safety profile; and uses thereof for treating CNS disorder and obesity disorders including diabetes, hyperglycemia, hyperlipidemia or hypercholesterolemia.

Compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions) comprising tannic acids, particularly tannic acids which are D-amino acid oxidase inhibitor with superior potency, purity and safety profile; and uses thereof for treating CNS disorder and obesity disorders including diabetes, hyperglycemia, hyperlipidemia or hypercholesterolemia.