An application of Longhu Rendan in preparing a medicament for preventing and/or treating liver fibrosis. The Longhu Rendan has significant effect in improving fibrosis, and its effect in anti-liver fibrosis and liver protection is equivalent to those of a positive drug silybin.

Provided are a cosmetic composition, a food composition, a pharmaceutical composition, and an over-the-counter (OTC) composition for skin elasticity enhancement and skin wrinkle reduction, a composition for promoting differentiation or proliferation of human adipose-derived stem cells, and a method of enhancing skin elasticity including administering the compositions to an individual other than a human, each composition including at least one substance selected from the group consisting of formononetin, emodin, artepillin C, carnosic acid, palmitamide, sodium guaiazulene sulfonate, caffeic acid, acetyl mandelic acid, laccaic acid, ubiquinone, hydroxycinnamic acid, xanthophyll, raspberry ketone, gallic acid, terpineol, sodium mannose phosphate, tropolone, glycyrrhetinic acid, lanosterol, sodium riboflavin phosphate, menadione, thioctic acid, lactoflavin, onion extract, rice bran extract, bamboo extract, carrot extract, Hibiscus extract, Magnoliae cortex extract, Aloe vera extract, and fractions of the extracts as an active ingredient.

Provided are a cosmetic composition, a food composition, a pharmaceutical composition, and an over-the-counter (OTC) composition for skin elasticity enhancement and skin wrinkle reduction, a composition for promoting differentiation or proliferation of human adipose-derived stem cells, and a method of enhancing skin elasticity including administering the compositions to an individual other than a human, each composition including at least one substance selected from the group consisting of formononetin, emodin, artepillin C, carnosic acid, palmitamide, sodium guaiazulene sulfonate, caffeic acid, acetyl mandelic acid, laccaic acid, ubiquinone, hydroxycinnamic acid, xanthophyll, raspberry ketone, gallic acid, terpineol, sodium mannose phosphate, tropolone, glycyrrhetinic acid, lanosterol, sodium riboflavin phosphate, menadione, thioctic acid, lactoflavin, onion extract, rice bran extract, bamboo extract, carrot extract, Hibiscus extract, Magnoliae cortex extract, Aloe vera extract, and fractions of the extracts as an active ingredient.

An application of Longhu Rendan in preparing a medicament for preventing and/or treating liver fibrosis. The Longhu Rendan has significant effect in improving fibrosis, and its effect in anti-liver fibrosis and liver protection is equivalent to those of a positive drug silybin.

An application of Longhu Rendan in preparing a medicament for preventing and/or treating liver fibrosis. The Longhu Rendan has significant effect in improving fibrosis, and its effect in anti-liver fibrosis and liver protection is equivalent to those of a positive drug silybin.

An application of Longhu Rendan in preparing a medicament for preventing and/or treating liver fibrosis. The Longhu Rendan has significant effect in improving fibrosis, and its effect in anti-liver fibrosis and liver protection is equivalent to those of a positive drug silybin.

An exemplary formulation including a specific weight ratio of Atractylodes macrocephala to other certain ingredients surprisingly had an antidiuretic effect which is opposite to what was expected from the common general knowledge. One aspect of such a formulation includes Atractylodes macrocephala; at least one other ingredient that can include at least one of Polyporus umbellatus; Poria cocos; Cinnamomum cassia (twig); and at least one of Alisma orientale and Alisma plantago-aquatica. The formulation can be formed with a weight ratio of Atractylodes macrocephala being greater than 25% with respect to the at least one other ingredient. These formulations may be useful in a method for the treatment of excessive urination, the method including administering an effective amount of a formulation as described herein to a patent in need thereof.

An exemplary formulation including a specific weight ratio of Atractylodes macrocephala to other certain ingredients surprisingly had an antidiuretic effect which is opposite to what was expected from the common general knowledge. One aspect of such a formulation includes Atractylodes macrocephala; at least one other ingredient that can include at least one of Polyporus umbellatus; Poria cocos; Cinnamomum cassia (twig); and at least one of Alisma orientale and Alisma plantago-aquatica. The formulation can be formed with a weight ratio of Atractylodes macrocephala being greater than 25% with respect to the at least one other ingredient. These formulations may be useful in a method for the treatment of excessive urination, the method including administering an effective amount of a formulation as described herein to a patent in need thereof.

An exemplary formulation including a specific weight ratio of Atractylodes macrocephala to other certain ingredients surprisingly had an antidiuretic effect which is opposite to what was expected from the common general knowledge. One aspect of such a formulation includes Atractylodes macrocephala; at least one other ingredient that can include at least one of Polyporus umbellatus; Poria cocos; Cinnamomum cassia (twig); and at least one of Alisma orientale and Alisma plantago-aquatica. The formulation can be formed with a weight ratio of Atractylodes macrocephala being greater than 25% with respect to the at least one other ingredient. These formulations may be useful in a method for the treatment of excessive urination, the method including administering an effective amount of a formulation as described herein to a patent in need thereof.

An application of Longhu Rendan in preparing a medicament for preventing and/or treating liver fibrosis The Longhu Rendan has significant effect in improving liver fibrosis, and its effect in anti-liver fibrosis and liver protection is equivalent to those of a positive drug silybin.