A61K36/65

CIS-GNETIN H AND TRANS-GNETIN H AS THERAPEUTIC AGENTS

The cis-isomer and trans-isomers of the plant-derived compound gnetin H are shown have anticancer properties, anti-inflammatory properties, and low toxicity. Therapeutic and prophylactic compositions that contain cis-gnetin H, trans-gnetin H, an derivatives thereof, as well as methods of making and using said compositions, are provided, cis-gnetin H and/or trans-gnetin H can be used in purified form or as a plant extract.

CIS-GNETIN H AND TRANS-GNETIN H AS THERAPEUTIC AGENTS

The cis-isomer and trans-isomers of the plant-derived compound gnetin H are shown have anticancer properties, anti-inflammatory properties, and low toxicity. Therapeutic and prophylactic compositions that contain cis-gnetin H, trans-gnetin H, an derivatives thereof, as well as methods of making and using said compositions, are provided, cis-gnetin H and/or trans-gnetin H can be used in purified form or as a plant extract.

TCM ADDITION AND SUBTRACTION PRESCRIPTION USED PREVENTION/TREATMENT OF METABOLIC SYNDROME AND COMPLICATIONS
20220047658 · 2022-02-17 · ·

A traditional Chinese medicine (TCM) addition and subtraction prescription for preventing/treating metabolic syndrome and comprises: Poria, Semen Coicis, Rhizoma Dioscoreae, Semen Euryales, and Semen Nelumbinis, and can be used for prevention and/or treatment of various dysmetabolic syndrome and complications, e.g., insulin resistance syndrome, diabetes mellitus, hyperlipemia, fatty liver disease, obesity, atherosclerosis, arterial sclerosis, and hypertension; the components of the TCM addition and subtraction prescription are simple and have no toxic or side effects to human body, without tolerance. The TCM addition and subtraction prescription may be orally administered for a long term, and may be appropriately increased or decreased according to disease condition; it may act to different extents, and would not result in hypoglycemia or hypotension decreased blood glucose or decreased blood pressure below normal range, etc. or toxic effects due to too high dose, and brings good news to patients with metabolic syndrome and its related complications.

TCM ADDITION AND SUBTRACTION PRESCRIPTION USED PREVENTION/TREATMENT OF METABOLIC SYNDROME AND COMPLICATIONS
20220047658 · 2022-02-17 · ·

A traditional Chinese medicine (TCM) addition and subtraction prescription for preventing/treating metabolic syndrome and comprises: Poria, Semen Coicis, Rhizoma Dioscoreae, Semen Euryales, and Semen Nelumbinis, and can be used for prevention and/or treatment of various dysmetabolic syndrome and complications, e.g., insulin resistance syndrome, diabetes mellitus, hyperlipemia, fatty liver disease, obesity, atherosclerosis, arterial sclerosis, and hypertension; the components of the TCM addition and subtraction prescription are simple and have no toxic or side effects to human body, without tolerance. The TCM addition and subtraction prescription may be orally administered for a long term, and may be appropriately increased or decreased according to disease condition; it may act to different extents, and would not result in hypoglycemia or hypotension decreased blood glucose or decreased blood pressure below normal range, etc. or toxic effects due to too high dose, and brings good news to patients with metabolic syndrome and its related complications.

PHARMACEUTICAL COMPOSITION FOR TREATING INFERTILITY, AND PREPARATION METHOD AND USE THEREOF
20170246230 · 2017-08-31 ·

The present invention provides a drug combination for the treatment of infertility and its crude drug comprises the medical ingredients with their weight proportions listed as below: 10-20 amounts by weight of Rehmannia, 10-20 amounts by weight of Chinese Peony, 10-20 amounts by weight of Asiatic Dogwood, 10-20 amounts by weight of Chinese Yam, 10-20 amounts by weight of Poria, 15-25 amounts by weight of Astragalus, 15-25 amounts by weight of Codonopsis, 10-20 amounts by weight of Epimedium and 10-20 amounts by weight of Jujube. The compatibility of this drug combination invented is precise, appropriate and possess outstanding curative effects. As shown in many experiments, the drug combination invented is safe and reliable, its toxic & side-effect is low and it has obvious improvement effects on female infertility caused by androgen, fallopian tube inflammation, tubal blockage and other factors. Furthermore, it can not only significantly improve the success rate of pregnancy, but also improve immunity and enhance the body's anti-fatigue and hypoxia tolerance. In short, the invention provides a safe and reliable new choice for clinical medication.

PHARMACEUTICAL COMPOSITION FOR TREATING INFERTILITY, AND PREPARATION METHOD AND USE THEREOF
20170246230 · 2017-08-31 ·

The present invention provides a drug combination for the treatment of infertility and its crude drug comprises the medical ingredients with their weight proportions listed as below: 10-20 amounts by weight of Rehmannia, 10-20 amounts by weight of Chinese Peony, 10-20 amounts by weight of Asiatic Dogwood, 10-20 amounts by weight of Chinese Yam, 10-20 amounts by weight of Poria, 15-25 amounts by weight of Astragalus, 15-25 amounts by weight of Codonopsis, 10-20 amounts by weight of Epimedium and 10-20 amounts by weight of Jujube. The compatibility of this drug combination invented is precise, appropriate and possess outstanding curative effects. As shown in many experiments, the drug combination invented is safe and reliable, its toxic & side-effect is low and it has obvious improvement effects on female infertility caused by androgen, fallopian tube inflammation, tubal blockage and other factors. Furthermore, it can not only significantly improve the success rate of pregnancy, but also improve immunity and enhance the body's anti-fatigue and hypoxia tolerance. In short, the invention provides a safe and reliable new choice for clinical medication.

PHARMACEUTICAL COMPOSITION FOR TREATING INFERTILITY, AND PREPARATION METHOD AND USE THEREOF
20170246230 · 2017-08-31 ·

The present invention provides a drug combination for the treatment of infertility and its crude drug comprises the medical ingredients with their weight proportions listed as below: 10-20 amounts by weight of Rehmannia, 10-20 amounts by weight of Chinese Peony, 10-20 amounts by weight of Asiatic Dogwood, 10-20 amounts by weight of Chinese Yam, 10-20 amounts by weight of Poria, 15-25 amounts by weight of Astragalus, 15-25 amounts by weight of Codonopsis, 10-20 amounts by weight of Epimedium and 10-20 amounts by weight of Jujube. The compatibility of this drug combination invented is precise, appropriate and possess outstanding curative effects. As shown in many experiments, the drug combination invented is safe and reliable, its toxic & side-effect is low and it has obvious improvement effects on female infertility caused by androgen, fallopian tube inflammation, tubal blockage and other factors. Furthermore, it can not only significantly improve the success rate of pregnancy, but also improve immunity and enhance the body's anti-fatigue and hypoxia tolerance. In short, the invention provides a safe and reliable new choice for clinical medication.

Pharmaceutical compositions for treating cancer of genital system and preparation method therefor
09744206 · 2017-08-29 ·

A pharmaceutical composition for preventing and treating cancer of reproductive system and preparation method therefor. The pharmaceutical composition is prepared using one or more of the following as raw material: pinellia tuber, bighead atractylodes rhizome, gastralia tuber, liquorice root, Indian bread, white peony root, fresh ginger.

Pharmaceutical compositions for treating cancer of genital system and preparation method therefor
09744206 · 2017-08-29 ·

A pharmaceutical composition for preventing and treating cancer of reproductive system and preparation method therefor. The pharmaceutical composition is prepared using one or more of the following as raw material: pinellia tuber, bighead atractylodes rhizome, gastralia tuber, liquorice root, Indian bread, white peony root, fresh ginger.

PHARMACEUTICAL COMPOSITION CONTAINING COMBINATION EXTRACTS OF MOUTAN ROOT BARK, ANGELICA DAHURICA ROOT, BUPLEURUM ROOT OR FRACTIONS THEREOF FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDER

The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof. Specifically, the extract of the mixture of the present invention exhibits a recovery effect on mitochondrial function damage, a relieving effect on endoplasmic reticulum stress and also exhibits simultaneously an inhibitory effect on inflammatory response, which are remarkably improved compared with those exhibited in an in vitro single extract, and the extract of the mixture significantly exhibits an improvement effect on motor coordination and a protective effect on dopaminergic neurons in a Parkinson's disease animal model, and thus the extract of the mixture of the present invention or a fraction thereof can be useful as an active ingredient of a pharmaceutical composition for treating and preventing degenerative neurological disorders.