The present invention discloses a multifunctional traditional Chinese medicine health pillow. The health pillow is in an inverted concave shape; an outermost layer is a dense old coarse cloth sheet. The health pillow of the present invention not only treats cervical spondylosis, but also can activate blood circulation to dissipate blood stasis, reconcile yin and yang, regulate pulmonary function, regulate blood pressure and reduce blood lipid, treat insomnia, forgetfulness and neurasthenia, conduct effective hypnosis and sleep aid, and is more widely used in adjunctive therapy of cervical vertebra syndrome, scapulohumeral periarthritis, ankylosing spondylitis, lumbar muscle strain, lumbar vertebrae hyperplasia, lumbar disc herniation, sciatica, multiple peripheral neuritis, rheumatic fibrositis, atrophic lateral sclerosis, pain caused by bone degenerative change and pain caused by various soft tissue injuries.

The present invention discloses a multifunctional traditional Chinese medicine health pillow. The health pillow is in an inverted concave shape; an outermost layer is a dense old coarse cloth sheet. The health pillow of the present invention not only treats cervical spondylosis, but also can activate blood circulation to dissipate blood stasis, reconcile yin and yang, regulate pulmonary function, regulate blood pressure and reduce blood lipid, treat insomnia, forgetfulness and neurasthenia, conduct effective hypnosis and sleep aid, and is more widely used in adjunctive therapy of cervical vertebra syndrome, scapulohumeral periarthritis, ankylosing spondylitis, lumbar muscle strain, lumbar vertebrae hyperplasia, lumbar disc herniation, sciatica, multiple peripheral neuritis, rheumatic fibrositis, atrophic lateral sclerosis, pain caused by bone degenerative change and pain caused by various soft tissue injuries.

A macrocycle compound of general formula (X)

##STR00001##

in which Y.sub.1 represents a C(O)OH group or a group of formula (II)

##STR00002##

A macrocycle compound of general formula (X)

##STR00001##

in which Y.sub.1 represents a C(O)OH group or a group of formula (II)

##STR00002##

In one aspect, a composition for topical application is provided. The composition comprises a base. Dispersed within the base is elemental silver as a colloidal suspension, and plant extract from at least 6 plants. The plants are selected from the group consisting of Echinacea purpurea, Stellaria media, Aloe vera, Matricaria recutita, Hypericum perforatum, Calendula officinalis, Equisetum arvense, Symphytum officinale, Panax ginseng, Rumex crispus, Arctium lappa, Trifolium pratense, Chelidonium majus, Thuja occidentalis, Urtica dioica, Mahonia aquifolium, and Galium aparine.

In one aspect, a composition for topical application is provided. The composition comprises a base. Dispersed within the base is elemental silver as a colloidal suspension, and plant extract from at least 6 plants. The plants are selected from the group consisting of Echinacea purpurea, Stellaria media, Aloe vera, Matricaria recutita, Hypericum perforatum, Calendula officinalis, Equisetum arvense, Symphytum officinale, Panax ginseng, Rumex crispus, Arctium lappa, Trifolium pratense, Chelidonium majus, Thuja occidentalis, Urtica dioica, Mahonia aquifolium, and Galium aparine.

Disclosed herein are compositions and methods for treating, reducing or preventing oxidative stress in a subject. The compositions can be chewable confectionaries comprising a chewable base, one or more unprocessed phytochemical ingredients, and a sweetener comprising allulose. The unprocessed phytochemical ingredients can include ground plant materials selected from cinnamon, nutmeg, allspice, or combinations thereof. The chewable confectionary can exhibit a polyphenolic content of at least 100 g gallic acid equivalents (GAE) or greater, per gram of the chewable confectionary and an antioxidant capacity of at least 3,200 M Trolox equivalents per gram of the chewable confectionary, as determined by the oxygen radical absorbance (ORAC) assay. Kits, methods of making and using the chewable confectionary are also disclosed.

Disclosed herein are compositions and methods for treating, reducing or preventing oxidative stress in a subject. The compositions can be chewable confectionaries comprising a chewable base, one or more unprocessed phytochemical ingredients, and a sweetener comprising allulose. The unprocessed phytochemical ingredients can include ground plant materials selected from cinnamon, nutmeg, allspice, or combinations thereof. The chewable confectionary can exhibit a polyphenolic content of at least 100 g gallic acid equivalents (GAE) or greater, per gram of the chewable confectionary and an antioxidant capacity of at least 3,200 M Trolox equivalents per gram of the chewable confectionary, as determined by the oxygen radical absorbance (ORAC) assay. Kits, methods of making and using the chewable confectionary are also disclosed.

An herbal pharmaceutical compositions of California poppy and methods for the treatment of sleep disorders and dream-related disorders is disclosed. The formulation may be in the form of capsules, tablets, caplets or other oral dosage forms and comprises preferably 600 to 2400 mg of a ratio of 4-10 parts (wt) dried plant material to 1 part (wt) aqueous alcohol (50-90 vol % ethanol) extract that is equivalent to 3-12 grams of the dried herb top of California poppy and contain at least 0.8 wt % isoquinoline alkaloids. The composition may further comprise isoquinoline alkaloids whose composition contains Californidine, Escholtzine and Protopine. California poppy can also be used as a therapy for managing people that have sleep and dream disorders such as Post Traumatic Stress syndrome and similar conditions that induce nightmares as well as people using tranquilizer, antidepressant, antipsychotic, sedative, hypnotic and analgesic drugs.

An herbal pharmaceutical compositions of California poppy and methods for the treatment of sleep disorders and dream-related disorders is disclosed. The formulation may be in the form of capsules, tablets, caplets or other oral dosage forms and comprises preferably 600 to 2400 mg of a ratio of 4-10 parts (wt) dried plant material to 1 part (wt) aqueous alcohol (50-90 vol % ethanol) extract that is equivalent to 3-12 grams of the dried herb top of California poppy and contain at least 0.8 wt % isoquinoline alkaloids. The composition may further comprise isoquinoline alkaloids whose composition contains Californidine, Escholtzine and Protopine. California poppy can also be used as a therapy for managing people that have sleep and dream disorders such as Post Traumatic Stress syndrome and similar conditions that induce nightmares as well as people using tranquilizer, antidepressant, antipsychotic, sedative, hypnotic and analgesic drugs.