Provided herein are compositions and methods of reducing certain psychoactive and physiological effects of tetrahydrocannabinol (THC), some of which may be undesirable, while preserving beneficial effects of cannabis in a human in need thereof. The methods described involve administration of therapeutically effective amounts of guineensine. Also, provided are compositions wherein guineensine is part of an herbal composition and is formulated for sublingual delivery.

Provided herein are compositions and methods of reducing certain psychoactive and physiological effects of tetrahydrocannabinol (THC), some of which may be undesirable, while preserving beneficial effects of cannabis in a human in need thereof. The methods described involve administration of therapeutically effective amounts of guineensine. Also, provided are compositions wherein guineensine is part of an herbal composition and is formulated for sublingual delivery.

Provided herein are compositions and methods of reducing certain psychoactive and physiological effects of tetrahydrocannabinol (THC), some of which may be undesirable, while preserving beneficial effects of cannabis in a human in need thereof. The methods described involve administration of therapeutically effective amounts of guineensine. Also, provided are compositions wherein guineensine is part of an herbal composition and is formulated for sublingual delivery.

A method for preparing a liquid dietary supplement includes extracting kavalactones from a Kava plant, heating water to approximately 160° Fahrenheit, and mixing kavalactones with sugar in a 1:2 ration creating a Kava/sugar mixture. The method also includes pouring Kava/sugar and heated water into a mixer, mixing, for approximately twenty (20) minutes, and pumping mixed Kava/sugar through a filter bag generating a slurry. Further the method includes adding the slurry to water heated to 55° Fahrenheit and agitating the slurry and the water heated to 55° with a mixer.

A method for preparing a liquid dietary supplement includes extracting kavalactones from a Kava plant, heating water to approximately 160° Fahrenheit, and mixing kavalactones with sugar in a 1:2 ration creating a Kava/sugar mixture. The method also includes pouring Kava/sugar and heated water into a mixer, mixing, for approximately twenty (20) minutes, and pumping mixed Kava/sugar through a filter bag generating a slurry. Further the method includes adding the slurry to water heated to 55° Fahrenheit and agitating the slurry and the water heated to 55° with a mixer.

Disclosed are a Piper laetispicum extract and a preparation method therefor and a use thereof. The Piper laetispicum extract includes any one or more of sesamin, (2E,6E)-N-isobutyl-7-(3,4-methylenedioxyphenyl)heptadienamide, (2E,4E)-N-isobutyldodecane-2,4-dieneamide, (2E,4E)-N-isobutyl-15-phenylpentadeca-2,4-dieneamide, (2E,4E,14Z)—N-isobutyleicosane-2,4,14-trienamide, and (2E,4E)-N-isobutyl-13-phenyltrideca-2,4-dieneamide. The Piper laetispicum extract can prevent depression.

Disclosed are a Piper laetispicum extract and a preparation method therefor and a use thereof. The Piper laetispicum extract includes any one or more of sesamin, (2E,6E)-N-isobutyl-7-(3,4-methylenedioxyphenyl)heptadienamide, (2E,4E)-N-isobutyldodecane-2,4-dieneamide, (2E,4E)-N-isobutyl-15-phenylpentadeca-2,4-dieneamide, (2E,4E,14Z)—N-isobutyleicosane-2,4,14-trienamide, and (2E,4E)-N-isobutyl-13-phenyltrideca-2,4-dieneamide. The Piper laetispicum extract can prevent depression.

A method of preparing a liquid dietary supplement includes extracting kavalactones from a Kava plant. The method also includes heating water to a defined temperature and providing the kavalactones and the heated water to the homogenizer. Further, the method includes homogenizing the mixture and generating a slurry of Kava and water. Further still, the method includes agitating the slurry and the water with a mixer.

A method of preparing a liquid dietary supplement includes extracting kavalactones from a Kava plant. The method also includes heating water to a defined temperature and providing the kavalactones and the heated water to the homogenizer. Further, the method includes homogenizing the mixture and generating a slurry of Kava and water. Further still, the method includes agitating the slurry and the water with a mixer.

A method for preparing a liquid dietary supplement includes extracting kavalactones from a Kava plant, heating water to approximately 160° Fahrenheit, and mixing kavalactones with sugar in a 1:2 ration creating a Kava/sugar mixture. The method also includes pouring Kava/sugar and heated water into a mixer, mixing, for approximately twenty (20) minutes, and pumping mixed Kava/sugar through a filter bag generating a slurry. Further the method includes adding the slurry to water heated to 55° Fahrenheit and agitating the slurry and the water heated to 55° with a mixer.