Patent classifications
A61K36/69
Biomedically active and delivery site specific capsule-in-capsule liver supplement apparatus and method of use thereof
The invention comprises a biomedically active/delivery site specific capsule-in-capsule liver supplement and method of use thereof. A first set of constituents, of an outer capsule, of a capsule-in-capsule liver supplement, comprises one or more of choline and phosphatidylcholine; a second set of constituents, of an inner capsule, comprise one or more of methionine, glycyrrhetinic acid, silymarin, and phosphatidylcholine; and either capsule optionally contains one or more liver aiding/regulating natural products, where the outer capsule dissolves in the stomach and the inner capsule dissolves in the small intestine. Thus, the dual dissolution process in controlled environments results in complementary and synergistic delivery of liver regulating molecules in a bioavailable form ready for transport through the wall of the small intestine. Further, constituents of the capsule-in-capsule liver supplement include multiple inputs into the methionine cycle, which facilitates/synergistically aids the body's use of the methionine cycle, such as in liver regulation.
Methods of improving tolerability, pharmacodynamics, and efficacy of β-alanine and use therefor
The present invention relates in some aspects to compositions (e.g., pharmaceutical, nutritional compositions, etc.), formulations, and food or beverage products comprising, consisting essentially of, or consisting of (a) -alanine or a derivative of -alanine, and (b) at least one agent that inhibits the N-methyl D-aspartate (NMDA) pathway or a pathway which converges downstream with the NMDA pathway. The compositions, formulations, and food or beverage products are useful for enhancing physical performance, reducing -alanine-induced paraesthesia, and improving tolerance and compliance to higher doses of -alanine, thereby reducing the length of time it takes to achieve peak effect of -alanine, and increasing the magnitude of peak effect on physical performance in a human or animal.
Methods of improving tolerability, pharmacodynamics, and efficacy of β-alanine and use therefor
The present invention relates in some aspects to compositions (e.g., pharmaceutical, nutritional compositions, etc.), formulations, and food or beverage products comprising, consisting essentially of, or consisting of (a) -alanine or a derivative of -alanine, and (b) at least one agent that inhibits the N-methyl D-aspartate (NMDA) pathway or a pathway which converges downstream with the NMDA pathway. The compositions, formulations, and food or beverage products are useful for enhancing physical performance, reducing -alanine-induced paraesthesia, and improving tolerance and compliance to higher doses of -alanine, thereby reducing the length of time it takes to achieve peak effect of -alanine, and increasing the magnitude of peak effect on physical performance in a human or animal.
Methods of improving tolerability, pharmacodynamics, and efficacy of β-alanine and use therefor
The present invention relates in some aspects to compositions (e.g., pharmaceutical, nutritional compositions, etc.), formulations, and food or beverage products comprising, consisting essentially of, or consisting of (a) -alanine or a derivative of -alanine, and (b) at least one agent that inhibits the N-methyl D-aspartate (NMDA) pathway or a pathway which converges downstream with the NMDA pathway. The compositions, formulations, and food or beverage products are useful for enhancing physical performance, reducing -alanine-induced paraesthesia, and improving tolerance and compliance to higher doses of -alanine, thereby reducing the length of time it takes to achieve peak effect of -alanine, and increasing the magnitude of peak effect on physical performance in a human or animal.
PROCESS FOR PREPARING HERBAL EXTRACTS
The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (MilkvetchHuang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese AngelicaDang Gui) and Radix polygalae (Thinleaf milkwortYuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
PROCESS FOR PREPARING HERBAL EXTRACTS
The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (MilkvetchHuang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese AngelicaDang Gui) and Radix polygalae (Thinleaf milkwortYuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
PROCESS FOR PREPARING HERBAL EXTRACTS
The present invention relates to a process for preparing pharmaceutical compositions and other herbal products derived from herbs of Traditional Chinese Medicine (TCM), including Radix astragali (MilkvetchHuang Qi), Ligusticum chuanxiong (Chuan Xiong), Radix angelicae sinensis (Chinese AngelicaDang Gui) and Radix polygalae (Thinleaf milkwortYuan Zhi). The process includes a single extraction of the TCM herbs by heating in a hydro-alcoholic solvent, wherein the alcohol may be ethanol. FIG. 2 provides an overview of one embodiment of the process. The invention also relates to products of the process of the invention, and their use in the treatment of stroke and various neurological disorders.
BUCKWHEAT HONEY AND POVIDONE-IODINE WOUND HEALING DRESSING
The present invention is a method of treating acute and chronic wounds and skin conditions. The product comprises a composition or formulation comprising a mixture of buckwheat honey and povidone-iodine. In one unique embodiment the composition is gelled. The composition is applied directly to a wound or a patient's skin or is impregnated on gauze or other similar material on a bandage or dressing for application to an exuding or non-exuding acute or chronic wound or skin condition.
BUCKWHEAT HONEY AND POVIDONE-IODINE WOUND HEALING DRESSING
The present invention is a method of treating acute and chronic wounds and skin conditions. The product comprises a composition or formulation comprising a mixture of buckwheat honey and povidone-iodine. In one unique embodiment the composition is gelled. The composition is applied directly to a wound or a patient's skin or is impregnated on gauze or other similar material on a bandage or dressing for application to an exuding or non-exuding acute or chronic wound or skin condition.
COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES
Disclosed herein is a pharmaceutical composition for preventing, alleviating or treating neurodegenerative diseases. The pharmaceutical composition contains, as active ingredients, Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum. The pharmaceutical composition is prepared by a method including the steps of: mixing Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum to obtain a mixture, and extracting the mixture to obtain a mixture extract; filtering the mixture extract; concentrating the mixture extract; and drying the mixture extract.