The disclosure relates to compositions and methods for delivery of magnesium. In one embodiment, the disclosure relates to a composition comprising a first plant based source of magnesium and a second plant based source of magnesium. In on embodiment, the disclosure relates to methods for delivering magnesium to the central nervous system of an individual,

The invention relates to a new orally administered composition, which in present embodiments is a standardized phytochemical formulation but other embodiments may contain designed molecules. This formulation is capable of suppressing inflammation in a variety of disease conditions having an underlying inflammatory component, including but not limited to cystic fibrosis, COPD, asthma, and pancreatitis. It is an objective of the invention to provide a non-toxic therapy, which exhibits anti-oxidant anti-inflammatory properties without deleterious side effects.

The invention relates to a new orally administered composition, which in present embodiments is a standardized phytochemical formulation but other embodiments may contain designed molecules. This formulation is capable of suppressing inflammation in a variety of disease conditions having an underlying inflammatory component, including but not limited to cystic fibrosis, COPD, asthma, and pancreatitis. It is an objective of the invention to provide a non-toxic therapy, which exhibits anti-oxidant anti-inflammatory properties without deleterious side effects.

The invention relates to a new orally administered composition, which in present embodiments is a standardized phytochemical formulation but other embodiments may contain designed molecules. This formulation is capable of suppressing inflammation in a variety of disease conditions having an underlying inflammatory component, including but not limited to cystic fibrosis, COPD, asthma, and pancreatitis. It is an objective of the invention to provide a non-toxic therapy, which exhibits anti-oxidant anti-inflammatory properties without deleterious side effects.

The present invention relates to a pharmaceutical composition comprising an Indigo Pulverata Levis extract or a fraction thereof as an effective ingredient for preventing or treating inflammatory bowel disease. Exhibiting the effect of reducing the activity and expression of inflammatory activation markers and alleviating the disease activity index of inflammatory bowel disease, an Indigo Pulverata Levis extract or a fraction thereof according to the present invention may be useful as an agent for preventing and treating inflammatory bowel disease.

The present invention relates to a pharmaceutical composition comprising an Indigo Pulverata Levis extract or a fraction thereof as an effective ingredient for preventing or treating inflammatory bowel disease. Exhibiting the effect of reducing the activity and expression of inflammatory activation markers and alleviating the disease activity index of inflammatory bowel disease, an Indigo Pulverata Levis extract or a fraction thereof according to the present invention may be useful as an agent for preventing and treating inflammatory bowel disease.

A topical TCM composition and topical preparation for a cervical disease, and preparation methods thereof are provided. The topical TCM composition is prepared from the following components in parts by weight: Cortex Ailanthi; fried Ginkgo nut; Phellodendron amurense; Cnidium monnieri fruit; Radix Sophorae Flavescentis; Sichuan pepper; Cyrtomium fortunei; Indigo naturalis; Ligustrum lucidum; Halloysitum Rubrum; Radix rehmanniae praeparata; Houttuynia Cordata; charred Zingiberis Rhizoma Recens; Radix Boehmeriae; Rhizoma Atractylodis; Chinese smartweed; Herba Patriniae; Radix et Rhizoma Rhei; Solanum nigrum; Rhizoma Bletillae; Radix Notoginseng; Fructus Piperis Longi; and licorice root.

A topical TCM composition and topical preparation for a cervical disease, and preparation methods thereof are provided. The topical TCM composition is prepared from the following components in parts by weight: Cortex Ailanthi; fried Ginkgo nut; Phellodendron amurense; Cnidium monnieri fruit; Radix Sophorae Flavescentis; Sichuan pepper; Cyrtomium fortunei; Indigo naturalis; Ligustrum lucidum; Halloysitum Rubrum; Radix rehmanniae praeparata; Houttuynia Cordata; charred Zingiberis Rhizoma Recens; Radix Boehmeriae; Rhizoma Atractylodis; Chinese smartweed; Herba Patriniae; Radix et Rhizoma Rhei; Solanum nigrum; Rhizoma Bletillae; Radix Notoginseng; Fructus Piperis Longi; and licorice root.

An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques. The objective is solved by A method for producing a nepodin-containing Rumex plant extract, the method comprising the following steps (1) to (5): (1) a step of subjecting a Rumex plant to an extraction treatment using a nepodin-dissolving solvent to obtain a crude Rumex plant extract; (2) a step of subjecting the crude Rumex plant extract to a water-adding treatment and/or concentration treatment to obtain a solid crude Rumex plant extract; (3) a step of subjecting the solid crude Rumex plant extract to a weak alkali treatment to obtain a weak alkali insoluble product; (4) a step of subjecting the weak alkali insoluble product to a strong alkali treatment to obtain a strong alkali soluble product; and (5) a step of subjecting the strong alkali soluble product to a neutralization treatment to obtain the nepodin-containing Rumex plant extract.

An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques. The objective is solved by A method for producing a nepodin-containing Rumex plant extract, the method comprising the following steps (1) to (5): (1) a step of subjecting a Rumex plant to an extraction treatment using a nepodin-dissolving solvent to obtain a crude Rumex plant extract; (2) a step of subjecting the crude Rumex plant extract to a water-adding treatment and/or concentration treatment to obtain a solid crude Rumex plant extract; (3) a step of subjecting the solid crude Rumex plant extract to a weak alkali treatment to obtain a weak alkali insoluble product; (4) a step of subjecting the weak alkali insoluble product to a strong alkali treatment to obtain a strong alkali soluble product; and (5) a step of subjecting the strong alkali soluble product to a neutralization treatment to obtain the nepodin-containing Rumex plant extract.