A method for reducing pathological cardiac hypertrophy and/or inducing physiological cardiac hypertrophy by administering Nigella sativa or an extract thereof to a subject in need thereof, especially to an athletic subject in order to reduce exercise-induced pathological cardiac hypertrophy. A composition comprising Nigella sativa for use in said method.

A method for reducing pathological cardiac hypertrophy and/or inducing physiological cardiac hypertrophy by administering Nigella sativa or an extract thereof to a subject in need thereof, especially to an athletic subject in order to reduce exercise-induced pathological cardiac hypertrophy. A composition comprising Nigella sativa for use in said method.

A method for reducing pathological cardiac hypertrophy and/or inducing physiological cardiac hypertrophy by administering Nigella sativa or an extract thereof to a subject in need thereof, especially to an athletic subject in order to reduce exercise-induced pathological cardiac hypertrophy. A composition comprising Nigella sativa for use in said method.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.

It is provided an anti-aging composition comprising at least one plant extract and a carrier, the at least one plant extract is at least one of Serenoa repens, Hypericum perforatum, Ilex paraguariensis, Ocimum tenuiflorum, Solidago virgaurea, Citrus sinensis, Humulus lupulus, Vitis vinifera, Andrographis paniculata, Hydrastis canadensis, Trigonella foenum-graecum, Berberis vulgaris, Crataegus monogyna, Taraxacum erythrospermum, Ilex paraguariensis, and a combination thereof.

It is provided an anti-aging composition comprising at least one plant extract and a carrier, the at least one plant extract is at least one of Serenoa repens, Hypericum perforatum, Ilex paraguariensis, Ocimum tenuiflorum, Solidago virgaurea, Citrus sinensis, Humulus lupulus, Vitis vinifera, Andrographis paniculata, Hydrastis canadensis, Trigonella foenum-graecum, Berberis vulgaris, Crataegus monogyna, Taraxacum erythrospermum, Ilex paraguariensis, and a combination thereof.