The present invention is about composition for preventing hair loss or promoting hair growth comprising indirubin derivatives; and one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin; as an active ingredient.

In addition, one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin of the present invention is a natural-derived composition with little toxicity to cells. Indirubin derivatives are stable compounds that have been found to have little toxicity to the human body, and therefore, when used in a mixture thereof, there are advantages in that they do not exhibit adverse effects on the human body, unlike conventional steroid drugs.

The present invention is about composition for preventing hair loss or promoting hair growth comprising indirubin derivatives; and one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin; as an active ingredient.

In addition, one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin of the present invention is a natural-derived composition with little toxicity to cells. Indirubin derivatives are stable compounds that have been found to have little toxicity to the human body, and therefore, when used in a mixture thereof, there are advantages in that they do not exhibit adverse effects on the human body, unlike conventional steroid drugs.

Implementations of a topical homeopathic formulation may include an active portion including a plurality of active ingredients and a base including a plurality of inactive ingredients. The plurality of active ingredients may include one of tinctures and homeopathic preparations of Apis mellifica, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Cactus grandifloras, Caulophyllum thalictroides, Cimicifuga racemose, Citrullus colocynthis, Cyclamen europaeum, Gelsemium Sempervirens, Gnaphalium polycephalum, Jonesia asoca, Juniperus Sabina, Kali carbonicum, Lilium tigrinum, Rhamnus californica, Tilia europaea, Viburnum opulus, and any combination thereof.

Implementations of a topical homeopathic formulation may include an active portion including a plurality of active ingredients and a base including a plurality of inactive ingredients. The plurality of active ingredients may include one of tinctures and homeopathic preparations of Apis mellifica, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Cactus grandifloras, Caulophyllum thalictroides, Cimicifuga racemose, Citrullus colocynthis, Cyclamen europaeum, Gelsemium Sempervirens, Gnaphalium polycephalum, Jonesia asoca, Juniperus Sabina, Kali carbonicum, Lilium tigrinum, Rhamnus californica, Tilia europaea, Viburnum opulus, and any combination thereof.

Implementations of a topical homeopathic formulation may include an active portion including a plurality of active ingredients and a base including a plurality of inactive ingredients. The plurality of active ingredients may include one of tinctures and homeopathic preparations of Apis mellifica, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Cactus grandifloras, Caulophyllum thalictroides, Cimicifuga racemose, Citrullus colocynthis, Cyclamen europaeum, Gelsemium Sempervirens, Gnaphalium polycephalum, Jonesia asoca, Juniperus Sabina, Kali carbonicum, Lilium tigrinum, Rhamnus californica, Tilia europaea, Viburnum opulus, and any combination thereof.

In a method of producing an anti-microbial extract, gesho matter is ground to a medium coarseness to form gesho particles. An amount of ethanol sufficient to dissolve a predetermined amount of soluble gesho material is added to the gesho particles. The ethanol and gesho particles are agitated sufficiently to maintain the gesho particles in suspension for a predetermined amount of time, thereby generating a gesho extract/ethanol solution. The gesho extract/ethanol solution is vacuum filtered after the agitating step, thereby separating the gesho extract/ethanol solution from the gesho particles. The gesho extract/ethanol solution is concentrated so as to generate a viscous gesho liquid. The viscous gesho liquid is vacuum dried until the anti-microbial extract has a predetermined dryness. A drink includes a carbonated beverage dispensed in a bottle and an amount of gesho extract sufficient to act as a preservative of the drink.

In a method of making a drink, a first predetermined quantity of a sweetener phase containing a base salt is dispensed into a bottle. A second predetermined quantity of an acidic aqueous phase is dispensed to the bottle. The bottle is sealed with a substantially airtight seal within a predetermined amount of time after the first predetermined quantity and the second predetermined quantity has been dispensed into the bottle. A fortified drink includes a first predetermined quantity of a sweetener phase, a second predetermined quantity of an acidic aqueous phase, a predetermined quantity of gesho extract and a pharmaceutically effective amount of an additive.

Disclosed are compositions comprising Rhamnus prinoides (GESHO) extract or fragments thereof and methods of using Gesho extract for the inhibition of biofilm formation.

Disclosed are compositions comprising Rhamnus prinoides (GESHO) extract or fragments thereof and methods of using Gesho extract for the inhibition of biofilm formation.

Compositions and methods for treating and/or preventing hangover are disclosed. In certain embodiments, the compositions include at least one B vitamin, activated charcoal, at least one mineral, and at least one herbal extract.