In a method for MRI of an object, spins of a first material and spins of a second material are excited. An in-phase echo signal is acquired when the spins are in-phase and an out-of-phase echo signal is acquired, when the spins are out of phase. A first image for the first material and/or a second image for the second material is generated by a computing unit depending on the in-phase echo signal and the out-of-phase echo signal. For acquiring the out-of-phase echo signal, a momentum space is sampled asymmetrically in a read-out direction.

A system and method is provided for acquisition of magnetic resonance fingerprinting (“MRF”) data that includes determining a non-locally sequential sampling pattern for a Cartesian grid of k-space, performing a series of sequence blocks using acquisition parameters that vary between sequence blocks to acquire MRF data from a subject using the Cartesian grid of k-space and the determined non-locally sequential sampling pattern, assembling the MRF data into a series of signal evolutions, comparing the series of signal evolutions to a dictionary of known signal evolutions to determine tissue properties of the subject, and generating a report indicating the tissue properties of the subject.

The invention relates to a fat suppressed diffusion image determination apparatus, a corresponding method and a corresponding computer program, for determining a diffusion weighted magnetic resonance image (DWI) of an object (10), the fat suppressed diffusion image determination apparatus (100) comprising: a diffusion reference image providing unit (110) for providing a diffusion reference MR image of the object (10), a fat image determination unit (120) for determining a fat image from the diffusion reference MR image, a diffusion weighted image providing unit (130) for providing a diffusion weighted MR image of the object, a fat suppressed image determination unit (140) for determining a fat suppressed diffusion weighted MR image using a combination of the diffusion weighted MR image and the fat image. The invention allows for a robust fat suppression in diffusion MRI with improved SNR and scan time trade-off.

A protocol to determine chemical shift-specific Ti constants in inhomogeneous magnetic fields is provided. Based on intermolecular double-quantum coherences and spatial encoding techniques, the method can resolve overlapped NMR spectral peaks in inhomogeneous magnetic fields acquired using conventional methods. With inversion recovery involved, the amplitude of spectral peak will be modulated by inversion recovery time. After fitting the spectral peak amplitude variation curve, the corresponding longitudinal relaxation time can be achieved. With the measured T.sub.1 values in inhomogeneous magnetic fields, insights into chemical exchange rates, signal optimization, and data quantitation can be obtained.

Provided are a method of obtaining a water-fat separation image and a magnetic resonance imaging (MRI) apparatus including a controller configured to obtain first partial k-space data, second partial k-space data, and third partial k-space data, respectively based on a first partial echo signal, a second partial echo signal, and a third partial echo signal, which are magnetic resonance signals corresponding to a plurality of echo times with respect to an object, obtain first reconstruction image data, second reconstruction image data, and third reconstruction image data with respect to the object, respectively based on the first partial k-space data, the second partial k-space data, and the third partial k-space data, and obtain first water image data, first fat image data, and first phase image data of the object, respectively based on the first reconstruction image data, the second reconstruction image data, and the third reconstruction image data, by using a Dixon technique.

Exemplary system, method and computer-accessible medium for remotely initiating a medical imaging scan(s) of a patient(s), can include, for example, receiving, over a network, encrypted first information related to first parameters of the patient(s), determining second information related to image acquisition second parameters based on the first information, generating an imaging sequence(s) based on the second information, and initiating, remotely from the patient(s), the medical imaging scan(s) based on the imaging sequence(s). The medical imaging scan(s) can be a magnetic resonance imaging (“MRI”) sequence(s). The image acquisition second parameters can be MRI acquisition parameters, and the imaging sequence(s) can be a gradient recalled echo (“GRE”) pulse sequence(s).

Systems and methods for high-resolution STAGE imaging can include acquisition of relatively low-resolution k-space datasets with two separate multi-echo GRE sequences. The multi-echo GRE sequences can correspond to separate and distinct flip angles. Various techniques for combining the low-resolution k-space datasets to generate a relatively high-resolution k-space are described. These techniques can involve combining low-resolution k-space datasets associated with various echo types. The STAGE imaging approaches described herein allow for rapid imaging, enhanced image resolution with relatively small or no increase in MR data acquisition time.

An exemplary system, method and computer-accessible medium for characterizing a microstructure of a prostate of a patient can be provided, which can include, for example, generating a magnetic resonance (MR) radiofrequency (RF) pulse(s) by varying (i) a diffusion time, (ii) a diffusion gradient direction, (iii) a diffusion gradient pulse width, or (iv) a diffusion gradient pulse shape, applying the MR RF pulse(s) to the prostate of the patient, receiving a resultant MR signal from the prostate of the patient that can be based on the MR RF pulse(s), determining information regarding a plurality of compartments for the prostate from the resultant MR signal by varying an echo time or a mixing time, and characterizing the microstructure for each of the compartments by applying a microstructural model(s) to each of the compartments.

A synergized pulsing-imaging network is described. A method of optimizing a magnetic resonance imaging (MRI) system includes optimizing, by a synergized pulsing-imaging network (SPIN) circuitry a pulse sequence based, at least in part, on a loss function associated with a reconstruction network. The method further includes optimizing, by the SPIN circuitry, the reconstruction network based, at least in part, on intermediate raw MRI data and based, at least in part, on a ground truth MRI image data. The intermediate raw MRI data is determined based, at least in part on the pulse sequence.

Techniques are described for generating an MR image of an object using a multi spin-echo based imaging sequence with a plurality of k space segments using a preparation pulse. The technique included acquiring a first k-space dataset of the object using a first echo time and a first delay after the preparation pulse before the several spin-echoes are acquired. The technique further includes acquiring a second k space dataset of the object using a second echo time and a second delay after the preparation pulse, with at least one of the second echo time and the second delay time being different from the corresponding first echo time and the first delay time, generating a combined k space, and generating the MR image based on the combined k space dataset.