Stably consolidated compounds assembled from a statin and a metformin analog, and metabolically labile dual prodrugs assembled from the same, methods of making both, and methods of using them to treat metabolic diseases such as cancers are described.

Stably consolidated compounds assembled from a statin and a metformin analog, and metabolically labile dual prodrugs assembled from the same, methods of making both, and methods of using them to treat metabolic diseases such as cancers are described.

The invention relates to the field of traditional Chinese medicine, in particular to provides traditional Chinese medicine compositions for the treatment of psoriasis, their preparations and their preparation methods. The Chinese medicine compositions of the invention are consisted of 20-80 parts of Rumex madaio, 20-80 parts of Radix sophora flavescens, 10-50 parts of Herba Siphonostegiae, 10-40 parts of Chinese pulsatilla chinensis, and 5-30 parts of Acacia catechu, by weight. The invention also includes the preparation methods of the traditional Chinese medicine compositions and the preparations containing the traditional Chinese medicine compositions and method for preparing the same. The pharmacological experiments and clinical experiments proved that the traditional Chinese medicine compositions of the invention have remarkable curative effects on psoriasis vulgaris, high cure rate, no toxic and side effects of hormones, and is suitable for the characteristics of psoriasis having long-term use due to the long-course of the diseases.

The invention relates to the field of traditional Chinese medicine, in particular to provides traditional Chinese medicine compositions for the treatment of psoriasis, their preparations and their preparation methods. The Chinese medicine compositions of the invention are consisted of 20-80 parts of Rumex madaio, 20-80 parts of Radix sophora flavescens, 10-50 parts of Herba Siphonostegiae, 10-40 parts of Chinese pulsatilla chinensis, and 5-30 parts of Acacia catechu, by weight. The invention also includes the preparation methods of the traditional Chinese medicine compositions and the preparations containing the traditional Chinese medicine compositions and method for preparing the same. The pharmacological experiments and clinical experiments proved that the traditional Chinese medicine compositions of the invention have remarkable curative effects on psoriasis vulgaris, high cure rate, no toxic and side effects of hormones, and is suitable for the characteristics of psoriasis having long-term use due to the long-course of the diseases.

The present disclosure provides a method of preparing an ebelin lactone or bacogenin A1 enriched composition from acid-hydrolyzed extract of Bacopa monnieri. Also provided is a composition prepared by the method. Advantageously, the present method may yield a cost effective product containing at least 10% ebelin lactone, which may result in an entirely new subjective experience with fully hydrolyzed Bacopa monnieri extract.

The present disclosure provides a method of preparing an ebelin lactone or bacogenin A1 enriched composition from acid-hydrolyzed extract of Bacopa monnieri. Also provided is a composition prepared by the method. Advantageously, the present method may yield a cost effective product containing at least 10% ebelin lactone, which may result in an entirely new subjective experience with fully hydrolyzed Bacopa monnieri extract.

A topical composition comprising an effective amount of a prebiotic capable of nourishing and encouraging skin microorganisms such as S. epidermidis to colonize the skin and supplant acne-causing bacteria such as P. acnes. Additional components can be used by S. epidermidis to create short chain fatty acids that inhibit growth of P. acnes. The preferred prebiotics are Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, and Chamomilla Recutita (Matricaria) Flower Extract. PEG-12 is used by S. epidermidis to create short chain fatty acids that inhibit P. acnes. The composition is highly effective in a method of treating acne.

A topical composition comprising an effective amount of a prebiotic capable of nourishing and encouraging skin microorganisms such as S. epidermidis to colonize the skin and supplant acne-causing bacteria such as P. acnes. Additional components can be used by S. epidermidis to create short chain fatty acids that inhibit growth of P. acnes. The preferred prebiotics are Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, and Chamomilla Recutita (Matricaria) Flower Extract. PEG-12 is used by S. epidermidis to create short chain fatty acids that inhibit P. acnes. The composition is highly effective in a method of treating acne.

A method of making an ointment that begins to work on contact, is all-natural and organic, is an anti-inflammatory ointment for pain relief and wound healing, which is to be applied to the skin. Further claimed is ointment produced by said method.

A method of making an ointment that begins to work on contact, is all-natural and organic, is an anti-inflammatory ointment for pain relief and wound healing, which is to be applied to the skin. Further claimed is ointment produced by said method.