The embodiments disclose a method, including suspending cannabinoid compound molecules and constituents in an aqueous solution, suspending Aloe Vera molecules and its constituents in an aqueous solution, wherein a combination of cannabinoid compound molecules and constituents and Aloe Vera molecules and its constituents may be used for suspending in an aqueous solution, encapsulating cannabinoid compound molecules and Aloe Vera molecules within a liposome in an aqueous solution, and blending the liposome encapsulated cannabinoid compound molecules and Aloe Vera molecules with other ingredients into a health beneficial product and delivery system for oral including sublingual ingestion and nasal spray and suppository insertion or topical application with a plurality of nano sensors by humans.

The present disclosure provides a composition comprising (a) exosome-like nanovesicles or exosomes and (b) a carrier, wherein the exosome-like nanovesicles or exosomes are extracted from Withania somnifera and methods of effecting a change in hair appearance, hair growth, hair pigmentation, hair follicle size or hair shaft size, comprising administering to the skin of a subject in need thereof an effective amount of such a composition.

The present disclosure provides a composition comprising (a) exosome-like nanovesicles or exosomes and (b) a carrier, wherein the exosome-like nanovesicles or exosomes are extracted from Withania somnifera and methods of effecting a change in hair appearance, hair growth, hair pigmentation, hair follicle size or hair shaft size, comprising administering to the skin of a subject in need thereof an effective amount of such a composition.

Provided is an aqueous solution as a continuous phase, the aqueous solution comprising: a first plurality of polymers; and a first plurality of active ingredients; and one or more nanoparticles, as a dispersed phase, the one or more nanoparticles comprising: a first plurality of carrier solvents; and a second plurality of active ingredients, wherein: the second plurality of active ingredients have at least 5 times higher absorption in-vivo when located inside the one or more nanoparticles compared to when administered in an aqueous solution.

Disclosed are compositions, methods of treatment using the compositions and methods of preparing the compositions for the treatment of acne vulgaris. The compositions include succinic acid and an API selected from the group consisting of salicylic acid, azelaic acid, picolinic acid, benzoyl peroxide, antibiotic, retinoid and combinations thereof in a pharmaceutically acceptable preparation. The compositions that include the combination of succinic acid and another API produce improved efficacy in treating acne vulgaris.

Disclosed are compositions, methods of treatment using the compositions and methods of preparing the compositions for the treatment of acne vulgaris. The compositions include succinic acid and an API selected from the group consisting of salicylic acid, azelaic acid, picolinic acid, benzoyl peroxide, antibiotic, retinoid and combinations thereof in a pharmaceutically acceptable preparation. The compositions that include the combination of succinic acid and another API produce improved efficacy in treating acne vulgaris.

A method of reducing anxiety in a non-human mammal by increasing brain serotonin levels, includes: down regulating in vivo levels of indigenous inflammatory cytokines in the nasal cavity of said non-human mammal by delivering an effective amount of an anti-inflammatory formula to said nasal cavity, which formula includes: at least one lipid-soluble antioxidant (which also functions as an anti-inflammatory agent) (the lipid-soluble antioxidant may be selected from the group consisting of alpha lipoic acid, aloe vera, omega 3 oil, N-acetylcysteine, cannabidiol, civet, oxytocin and combinations thereof); melatonin; tryptophan; and at least one essential oil. The most preferred antioxidant is N-acetylcysteine and the preferred essential oil is combination of chamomile, lavender and lemon oil.

A method of reducing anxiety in a non-human mammal by increasing brain serotonin levels, includes: down regulating in vivo levels of indigenous inflammatory cytokines in the nasal cavity of said non-human mammal by delivering an effective amount of an anti-inflammatory formula to said nasal cavity, which formula includes: at least one lipid-soluble antioxidant (which also functions as an anti-inflammatory agent) (the lipid-soluble antioxidant may be selected from the group consisting of alpha lipoic acid, aloe vera, omega 3 oil, N-acetylcysteine, cannabidiol, civet, oxytocin and combinations thereof); melatonin; tryptophan; and at least one essential oil. The most preferred antioxidant is N-acetylcysteine and the preferred essential oil is combination of chamomile, lavender and lemon oil.

The present invention relates to a method for determining the suitability of a subject to a skin barrier restoration therapy. Further provided is a method of selecting and preventing an IgE-related disease in a subject in need thereof.

The present invention relates to a method for determining the suitability of a subject to a skin barrier restoration therapy. Further provided is a method of selecting and preventing an IgE-related disease in a subject in need thereof.