Patent classifications
A61K36/896
Methods, compositions, and delivery systems for therapeutic skin treatments
Disclosed are skincare formulations, delivery systems and treatment methods containing an oligopeptide and a combination of antioxidants for topical application to the skin before and/or after dermatological procedures that affect the skin's barrier. The systems herein alleviate discomfort and enable rapid healing of irritated and damaged skin, and provide improved treatment outcomes for dermatological procedures. The disclosed topical formulations, delivery systems, and methods thereof provide enhanced penetration of the active ingredients to the skin while maintaining skin moisture and protecting sensitive skin after dermatological procedures for improvement of aesthetic skin properties. Also provided are methods for therapeutic treatment of dermatological conditions by topically applying, using, for example, a pre-moistened bio-cellulose mask, a formulation comprising (% w/w) at least 0.0001% palmitoyl sh-tripeptide-4 amide on an active basis and at least 0.1% Camellia sinensis leaf extract.
Methods, compositions, and delivery systems for therapeutic skin treatments
Disclosed are skincare formulations, delivery systems and treatment methods containing an oligopeptide and a combination of antioxidants for topical application to the skin before and/or after dermatological procedures that affect the skin's barrier. The systems herein alleviate discomfort and enable rapid healing of irritated and damaged skin, and provide improved treatment outcomes for dermatological procedures. The disclosed topical formulations, delivery systems, and methods thereof provide enhanced penetration of the active ingredients to the skin while maintaining skin moisture and protecting sensitive skin after dermatological procedures for improvement of aesthetic skin properties. Also provided are methods for therapeutic treatment of dermatological conditions by topically applying, using, for example, a pre-moistened bio-cellulose mask, a formulation comprising (% w/w) at least 0.0001% palmitoyl sh-tripeptide-4 amide on an active basis and at least 0.1% Camellia sinensis leaf extract.
Traditional Chinese medicine composition for treating diseases caused by human papillomavirus, preparation method and use thereof
The present invention discloses a traditional Chinese medicine composition for treating diseases caused by human papillomavirus, a preparation method and use thereof. The traditional Chinese medicine composition comprises: 15-60 parts of Rhizoma Smilacis Glabrae, 7.5-30 parts of Sophora Flavescens, 10-40 parts of Herba Hedyotidis Diffusae, 10-40 parts of Herba Taraxaci, 6-24 parts of Dysosma Versipellis, 7.5-30 parts of Nidus Vespae, 10-40 parts of Cortex Phellodendri, 2.5-10 parts of Fructus Bruceae, 7.5-30 parts of Fructus Cnidii, 3-12 parts of Radix Glycyrrhizae, 7.5-30 parts of Flos Lonicerae, 7.5-30 parts of Folium Isatidis, 5-20 parts of Radix Semiaquilegiae, and 1000-2000 parts of 75% ethanol. The traditional Chinese medicine composition has good curative effect and good safety.
Traditional Chinese medicine composition for treating diseases caused by human papillomavirus, preparation method and use thereof
The present invention discloses a traditional Chinese medicine composition for treating diseases caused by human papillomavirus, a preparation method and use thereof. The traditional Chinese medicine composition comprises: 15-60 parts of Rhizoma Smilacis Glabrae, 7.5-30 parts of Sophora Flavescens, 10-40 parts of Herba Hedyotidis Diffusae, 10-40 parts of Herba Taraxaci, 6-24 parts of Dysosma Versipellis, 7.5-30 parts of Nidus Vespae, 10-40 parts of Cortex Phellodendri, 2.5-10 parts of Fructus Bruceae, 7.5-30 parts of Fructus Cnidii, 3-12 parts of Radix Glycyrrhizae, 7.5-30 parts of Flos Lonicerae, 7.5-30 parts of Folium Isatidis, 5-20 parts of Radix Semiaquilegiae, and 1000-2000 parts of 75% ethanol. The traditional Chinese medicine composition has good curative effect and good safety.
COMPOSITIONS WITH AGENTS FOR MITIGATING METHANOGENESIS IN ANIMALS AND RELATED METHODS
Embodiments herein relate to compositions herein can include one or more of a tomato extract, a rhubarb extract, a garlic extract, a cashew shell composition, and a saponin composition, wherein the composition prevents or reduces methanogenesis in animals. Embodiments herein also relate to compositions including one or more of glycoalkaloids, saponins, anthraquinones, anacardic acid, and allicin and methods for using the same for mitigating methanogenesis in animals. In an embodiment, a composition can include glycoalkaloids, such as α-tomatine, that can prevent methanogenesis. In an embodiment, a method of processing animal feed is included. In an embodiment, a method of treating an animal to reduce methanogenesis is included. Other embodiments are also included herein.
COMPOSITIONS WITH AGENTS FOR MITIGATING METHANOGENESIS IN ANIMALS AND RELATED METHODS
Embodiments herein relate to compositions herein can include one or more of a tomato extract, a rhubarb extract, a garlic extract, a cashew shell composition, and a saponin composition, wherein the composition prevents or reduces methanogenesis in animals. Embodiments herein also relate to compositions including one or more of glycoalkaloids, saponins, anthraquinones, anacardic acid, and allicin and methods for using the same for mitigating methanogenesis in animals. In an embodiment, a composition can include glycoalkaloids, such as α-tomatine, that can prevent methanogenesis. In an embodiment, a method of processing animal feed is included. In an embodiment, a method of treating an animal to reduce methanogenesis is included. Other embodiments are also included herein.
SUPPLEMENT THAT ENHANCES INTRACELLULAR CONCENTRATION OF BIOACTIVE MOLECULES THROUGH INHIBITION OF MULTIDRUG RESISTANT (MDR) EFFLUX PUMPS
Described is a natural product-containing supplement that enhances intracellular concentration of bioactive molecules through inhibition of MDR efflux pumps. Specifically described are dosage forms for administration to a subject, the dosage forms having at least four ingredients selected from the group consisting of apigenin, cannabidiol, chrysin, harmine, caffeic acid, piperine, nobiletin, Hypericum perforatum extract, bee propolis, oleanolic acid, biochanin, luteolin, vanillin, honokiol, pterostilbene, and withaferin A. Upon administration to a mammalian subject, the dosage forms generally inhibit mis-regulated MDR efflux pumps that are responsible for pushing out good nutrients from the cell—thus increasing intracellular concentration of health-promoting compounds.
SUPPLEMENT THAT ENHANCES INTRACELLULAR CONCENTRATION OF BIOACTIVE MOLECULES THROUGH INHIBITION OF MULTIDRUG RESISTANT (MDR) EFFLUX PUMPS
Described is a natural product-containing supplement that enhances intracellular concentration of bioactive molecules through inhibition of MDR efflux pumps. Specifically described are dosage forms for administration to a subject, the dosage forms having at least four ingredients selected from the group consisting of apigenin, cannabidiol, chrysin, harmine, caffeic acid, piperine, nobiletin, Hypericum perforatum extract, bee propolis, oleanolic acid, biochanin, luteolin, vanillin, honokiol, pterostilbene, and withaferin A. Upon administration to a mammalian subject, the dosage forms generally inhibit mis-regulated MDR efflux pumps that are responsible for pushing out good nutrients from the cell—thus increasing intracellular concentration of health-promoting compounds.
FEED SUPPLEMENTS
Disclosed herein are embodiments of a combination and/or composition comprising a growth factor and one or more of silica, mineral clay, glucan, mannans, endoglucanohydrolase, yucca, quillaja, metal chelate, chromium compound, probiotic, polyphenol, direct fed microbial, copper species, vitamin, allicin, alliin, alliinase, yeast, growth promotant, preservative, antimicrobial, or vaccine. The growth factor may be an active growth factor such as an active insulin-like growth factor. Also disclosed are methods of administering the combination and/or composition to an animal. The combination and/or composition may provide a beneficial effect to the animal upon administration, such as, but not limited to, improved immune function, metabolism, milk production, growth, feed conversion, fertilization, reproduction, oocyte quality in a ruminant undergoing superovulation, embryo viability, muscle growth, muscle percentage, heart muscle development, egg product and/or quality, sperm production and/or quality, meat quality, or a combination thereof.
FEED SUPPLEMENTS
Disclosed herein are embodiments of a combination and/or composition comprising a growth factor and one or more of silica, mineral clay, glucan, mannans, endoglucanohydrolase, yucca, quillaja, metal chelate, chromium compound, probiotic, polyphenol, direct fed microbial, copper species, vitamin, allicin, alliin, alliinase, yeast, growth promotant, preservative, antimicrobial, or vaccine. The growth factor may be an active growth factor such as an active insulin-like growth factor. Also disclosed are methods of administering the combination and/or composition to an animal. The combination and/or composition may provide a beneficial effect to the animal upon administration, such as, but not limited to, improved immune function, metabolism, milk production, growth, feed conversion, fertilization, reproduction, oocyte quality in a ruminant undergoing superovulation, embryo viability, muscle growth, muscle percentage, heart muscle development, egg product and/or quality, sperm production and/or quality, meat quality, or a combination thereof.