Techniques are disclosed based on balanced steady state free precession sequence. The techniques include determining a readout gradient of climbing period, platform period, and descent period, and performing a balanced steady state free precession sequence in which the readout gradient is applied in the readout direction, the analog-to-digital conversion module for collecting k-space data is activated during the climbing period maintained in the on state during the platform period, and deactivated during the descent period. The technique includes converting the k-space data collected by the analog-to-digital conversion module into uniform k-space data and generating a magnetic resonance image based on the uniform k-space data. The techniques yield more running time of the readout gradient for data acquisition, reduce the data reading time, and shorten the scanning time. The techniques also reduce the accumulated phase of the field non-uniformity in the echo interval to reduce black band artifacts.

Systems and methods are provided for susceptibility contrast imaging of nanoparticles at low magnetic fields. A susceptibility-based MRI technique, such as imaging with a balanced steady-state free precession (bSSFP) pulse sequence, may be used for imaging a contrast agent such as biocompatible superparamagnetic nanoparticles at ultra-low fields. The contrast agent and imaging technique may be used to improving the visibility of anatomical structures and detecting diseases, such as cancer, with low-field MRI.

A method for recording a magnetic resonance image data set includes providing a magnetic resonance sequence. The magnetic resonance sequence includes at least one radio-frequency pulse and a slice-selection gradient pulse applied during or before the radio-frequency pulse, which is configured as non-constant. The method includes providing at least one correction term for compensating a magnetic field change of the slice-selection gradient pulse. The magnetic field change is ascertained via a transfer characteristic of the gradient system of the magnetic resonance system. The method also includes recording at least one magnetic resonance image data set with the magnetic resonance sequence using the correction term.

A method for recording a magnetic resonance image dataset includes providing a magnetic resonance sequence with a series of sequence blocks, and providing at least one correction term to compensate for a magnetic field change. The magnetic field change is produced as a change of an actual magnetic field compared to a setpoint magnetic field by gradient pulses. The magnetic field change is established via a transfer characteristic of the gradient system of the magnetic resonance installation. The at least one correction term is used to compensate for the magnetic field change, and at least one magnetic resonance image dataset is recorded with the magnetic resonance sequence using the correction term.

The present disclosure provides a system for MRI. The system may obtain a plurality of sets of k-space data corresponding to a plurality of frames. Each of the plurality of sets of k-space data may be collected, using an MRI scanner in one of the plurality of frames, simultaneously from a plurality of slice locations of a subject with a waiting time after a preparation pulse is applied. The system may generate a plurality of quantitative maps of the plurality of slice locations based on the plurality of sets of k-space data. Phase modulation may be applied to at least one target slice location of the plurality of slice locations in the plurality of frames for slice separation.

A low-field magnetic resonance imaging (MRI) system. The system includes a plurality of magnetics components comprising at least one first magnetics component configured to produce a low-field main magnetic field B.sub.0 and at least one second magnetics component configured to acquire magnetic resonance data when operated, and at least one controller configured to operate one or more of the plurality of magnetics components in accordance with at least one low-field zero echo time (LF-ZTE) pulse sequence.

Some aspects of the present disclosure relate to systems and methods for magnetic resonance thermometry. In one embodiment, a preliminary balanced steady state free precession (bSSFP) magnetic resonance imaging pulse sequence is applied to an area of interest of a subject. Based on bSSFP image phases, a relationship between frequency and image phase associated with the area of interest can be determined and a bSSFP magnetic resonance imaging pulse sequence applied for temperature change measurement during and/or after focused energy is applied to the subject. Based on image phase change associated with temperature change and using the determined relationship between frequency and image phase, a change in the resonance frequency associated with the target area due to the application of the focused energy can be determined, and the temperature change can be determined based on the determined change in the resonance frequency.

A magnetic resonance fingerprinting (MRF) method for determining parameter values in pixels of an examination object can use a magnetic resonance system with, for example, a constant magnetic field strength (e.g. of less than 1.5 tesla or a constant magnetic field strength of less than 0.5 tesla). The MRF method can be adapted for conditions that prevail with such low-field magnetic resonance systems, thus enabling the parameter values to be advantageously determined efficiently while simultaneously maintaining a high degree of quality.

The MRI apparatus includes a processor configured to apply a gradient echo pulse sequence that makes a sum of gradients applied during one repetition time (TR) in a slice selection direction, a phase encoding direction, and a frequency encoding direction equal zero and maintains spins in an object in a steady state; alternately apply, while the gradient echo pulse sequence is continuously applied, a first radio frequency (RF) pulse having a first flip angle and a second RF pulse having a second flip angle that is different from the first flip angle at each TR interval; and generate an MR image based on an echo signal acquired when the spins are in the steady state.

A tissue type fraction within a biological object is determined by a phase-cycled acquisition of several images of the object and deriving a complex signal profile for each voxel of the acquired images; generating a multidimensional dictionary of simulated signal profiles, wherein each simulated signal profile is configured for simulating the previously derived complex signal profile; using a weight optimization algorithm configured for expressing the complex signal profile as a weighted sum of the simulated signal profiles, wherein the weight optimization algorithm provides as output for each voxel a matrix M of optimized weights; for each voxel and each dimension of the obtained matrix M, extracting from the matrix M a distribution of the obtained optimized weights; and determining a type of tissue composing each voxel from the obtained distributions.