The present disclosure includes provides methods for assessing resting-state fMRI functional connectivity, resting-state MEGI functional connectivity, and/or task-based spatiotemporal auditory cortical activity latency in a subject to detect, monitor, and/or diagnose Tinnitus, with or without hearing impairment. The present disclosure also provides systems, devices, and methods for diagnosing Tinnitus and/or hearing impairment in a subject. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.

A medical data processing apparatus includes a memory and processing circuitry. The memory stores a learned model including an input layer to which first MR data and second MR data having the same imaging target as the first MR data and an imaging parameter different from the first MR data are inputted, an output layer from which third MR data is output with a missing portion of the first MR data restored, and at least one intermediate layer arranged between the input layer and the output layer. The processing circuitry generates third MR data relating to the subject, from the first MR data serving as a process target and relating to the subject and the second MR data relating to the subject and acquired by an imaging parameter different from the first MR data serving as the process target, in accordance with the learned model.

Magnetic resonance fingerprinting (“MRF”) techniques in which T1, T2, and T2* are simultaneously quantified using a combined gradient echo and spin echo acquisition with integrated B1 correction are described. The values for T2 and T2* can be estimated separately, but using the same underlying dictionary. This approach enables a smaller dictionary size that is easily manageable, and also reduced error propagation. Moreover, by using echo planar imaging (“EPI”) readouts, the raw MRF images will have higher signal-to-noise ratio (“SNR”) relative images acquired using spiral-based MRF techiques. The EPI-based images are also relatively free of artifacts. Together, these advantages lead to the need for far fewer frames, thereby enabling much faster acquisitions. Moreover, offline reconstruction is not needed, allowing for a more straightforward implementation of MRF.

The present disclosure provides a system for MRI. The system may obtain a plurality of echo signals relating to a subject that are excited by an MRI pulse sequence applied to the subject. The system may perform a quantitative measurement on the subject based on the plurality of echo signals. The MRI pulse sequence may include a CEST module configured to selectively excite exchangeable protons or exchangeable molecules in the subject, an RF excitation pulse applied after the CEST module configured to excite a plurality of gradient echoes, and one or more refocusing pulses applied after the RF excitation pulse. In some embodiments, the quantitative measurement may include determining various quantitative parameters including a T1, a T2, a T2*, an R2 value, an R2* value, an R2′, a B0 field, a pH value, an MWF, and an APT simultaneously.

The invention provides for a medical imaging system (100, 300). The execution of the machine executable instructions (110) causes a processor (102) to: receive (200) multiple diffusion weighted images (112) of a subject (318), wherein the multiple diffusion weighted images each have an assigned b-value, wherein the multiple diffusion weighted images each have an assigned diffusion weighting direction, wherein for a region of interest (309) there is at least one corresponding voxel (506) in each of the multiple diffusion weighted images; construct (202) a set of equations (114) for each of the at least one corresponding voxel, wherein the set of equations is constructed from an apparent diffusion equation for the assigned diffusion weighting direction of each of the multiple diffusion weighted images; solve (204) the set of equations for each voxel for the b.sub.0 value as an optimization; and construct (206) a image using the b.sub.0 value for each voxel.

Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.

A method for proton resonance frequency shift (PRF) and T.sub.1-based temperature mapping using a magnetic resonance imaging (MRI) system includes acquiring, using the MRI system, a set of magnetic resonance (MR) data from a region of interest of a subject by performing a variable-flip-angle multi-echo gradient-echo 3D stack-of-radial pulse sequence. The pulse sequence is configured to acquire radial k-space data in a plurality of segments, each segment acquired with each of a plurality of flip angles. The method further includes generating at least one T.sub.1 map based on the set of MR data, generating at least one PRF temperature map based on the set of MR data, generating at least one T.sub.1-based temperature map based on the set of MR data and displaying the PRF temperature map and the T.sub.1-based temperature map. In another embodiment, the MR data may be used to generate a plurality of quantitative parameter maps for each of the plurality of MR parameters such as T.sub.1, proton-density fat fraction (PDFF), and R.sub.2*.

The disclosure relates to a method for correcting image data acquired by a magnetic resonance device, a magnetic resonance device, and a computer program product. According to the method, first navigator data, image data, and second navigator data are acquired. Moreover, temperature values of the magnetic resonance device are determined. The image data is corrected based on the first navigator data, the second navigator data, and the temperature values.

A method for acquiring a magnetic resonance data set of an object under examination by a magnetic resonance system using a scan sequence is provided. The scan sequence includes a succession of sequence blocks, and in each sequence block, there is at least one sub-block including an excitation section and/or a detection section. An excitation section includes at least one excitation pulse, and in a detection section, an echo signal or an echo train is acquired as a scan signal. At least one item of motion information is provided for each sub-block. The motion information contains information about a movement of the object under examination within a duration of the sub-block. Some of the sub-blocks are automatically repeated. At least the sub-blocks having motion information that exceeds a threshold value are repeated. The threshold value defines a motion amplitude.

The present invention relates generally to medical imaging and, more particularly, relates to systems and methods for obtaining magnetic resonance (MR) images of tissues and organs (particularly of the heart) or parts thereof.