A method for measuring water exchange across the blood-brain barrier includes acquiring diffusion weighted (DW) arterial spin labeling (ASL) magnetic resonance imaging (Mill) signals. The method further includes determining optimal parameters to separate labeled water in capillary and brain tissue compartments. The method further includes estimating water exchange rate across the blood-brain barrier based on the DW ASL MRI signals and the optimal parameters, using a total generalized variation (TGV) regularized single-pass approximation (SPA) modeling algorithm.

Provided are devices and methods that deform tissue synchronous with an MR imaging cycle, as well as devices and methods for determination of dynamic determination of one or more mechanical properties of the tissue, including properties of muscle tissue. Such determination can be performed with and without imaging of the tissue being evaluated.

A system and method for analysis of 3D deformations and regional function of a heart includes: a magnetic resonance imaging (MRI) scanner configured to acquire three tagged volume data series with mutually perpendicular tag lines of a heart; a data storage device in communication with the MRI scanner and configured to store the three tagged volume data series; and an image processing machine in communication with data storage device. The image processing machine is configured to: model an intensity distribution around each voxel of each tagged volume data series as a moving sine wave front with a local frequency and an amplitude; and determine a phase and frequency for each voxel from the local frequency and amplitude and a displacement from a quotient of a phase difference and the local frequency.

Disclosed herein are systems and methods for correction of imaging-plane uniform magnetic field (Bo) inhomogeneity-induced magnetic resonance imaging (MRI) artifacts. The systems and methods can be implemented to improve the filtering and correction of arterial spin labeling (ASL) MRI data by forming a tagging dependent Z-spectrum (TADDZ) of ASL MRI data. In TADDZ, images are acquired via ASL, MRI after tagging blood water at a number of tagging, distances upstream and downstream of die MM system's imaging plane. A tagging distance dependent Z-spectrum is analyzed for each image to map the magnetic field inhomogeneity across the imaging plane. Along with.magnetic-field mapping, Z-spectrum analysts and data processing enables TADDZ to remove magnetic field inhomogeneity induced artifacts, resulting in more clear and clinically relevant perfusion imaging via. MRI

A magnetic resonance imaging method according to an embodiment includes performing a balanced SSFP sequence, repeatedly applies an excitation RF pulse to a subject at intervals of a repetition time and applies gradient magnetic field pulses balanced such that a time integral becomes zero within each interval of the repetition time, while further applying a spin labeling gradient magnetic field for generating one or more continuous spin labels within each interval of the repetition time.

In one embodiment, an MRI apparatus includes: a scanner equipped with at least a static magnetic field magnet configured to generate a static magnetic field, a gradient coil configured to apply gradient pulses, and an RF coil configured to apply RF pulses to an object and receive magnetic resonance signals from the object; and processing circuitry configured to set at least one pulse sequence which includes a labeling pulse for labeling fluid in the object, an excitation pulse applied after the labeling pulse, and a bipolar or unipolar velocity encoding gradient pulse for encoding velocity information of the fluid, and generate an image of the fluid from the magnetic resonance signals which the scanner acquires by performing the at least one pulse sequence.

A magnetic resonance imaging apparatus according to an embodiment includes a collection unit and a generation unit. The collection unit collects data of an imaging area over a plurality of time phases within a certain respiratory cycle after applying a labeling pulse to a labeling area in which cerebrospinal fluid flows under a task of respiration. The generation unit generates images of a plurality of time phases depicting the cerebrospinal fluid by using the collected data.

The embodiments disclosed herein relate to a method for generating time-resolved images of an examination object, which executes a cyclical movement, and to a magnetic resonance device, and a computer program product herefor. According to a first aspect, at least one spatial magnetization pattern with spatial magnetization differences is generated during a magnetization of the examination object. Furthermore, magnetic resonance signals of the examination object are acquired after generating the spatial magnetization pattern throughout at least one cycle of the cyclical movement. At least one k-space is undersampled here during the acquisition of the magnetic resonance signals. Time-resolved images are generated based on the acquired magnetic resonance signals.

A method for non-contrast enhanced 4D time resolved dynamic magnetic resonance angiography using arterial spin labeling of blood water as an endogenous tracer and a multiphase balanced steady state free precession readout is presented. Imaging can be accelerated with dynamic golden angle radial acquisitions and k-space weighted imaging contrast (KWIC) image reconstruction and it can be used with parallel imaging techniques. Quantitative tracer kinetic models can be formed allowing cerebral blood volume, cerebral blood flow and mean transit time to be estimated. Vascular compliance can also be assessed using 4D dMRA by synchronizing dMRA acquisitions with the systolic and diastolic phases of the cardiac cycle.

An image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to detect a region of body fluid flowing in a subject from time-series images acquired by scanning an imaging area including a tagged region to which a tagging pulse is applied and imaging the imaging area; generate a plurality of display images in which the detected body fluid region is displayed in a display mode determined based on a positional relation between the body fluid region and a boundary line, the boundary line determined based on the tagged region; and output time-series display images including the plurality of display images to be displayed on a display.