A61K38/39

Formulation with cannabinoids
11504416 · 2022-11-22 · ·

A food supplement comprising a therapeutically effective amount of a composition is described. The composition includes hydrolyzed collagen, hyaluronic acid, ascorbic acid, and glucosamine hydrochloride. The composition may also include a cannabinoid or prodrug, vitamin C, vitamin D, and/or vitamin E. The therapeutically effective amount of the composition is effective in alleviating at least one symptom of a degenerative joint disease in a human or may be used for the prophylaxis of the degenerative joint disease in the human. The at least one symptom of the degenerative joint disease in the human includes joint pain and mobility pain.

COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASE
20230054032 · 2023-02-23 ·

In various aspects and embodiments, the invention provides methods and pharmaceutical compositions for treating ocular disease, including ocular disease involving ocular vascular permeability or ocular inflammation. In various aspects and embodiments, the invention comprises administering about 1 μg to about 1 mg of collagen IV-derived biomimetic peptide or salt thereof to a patient by intraocular injection. Injections are provided at a frequency of from about monthly to about once every two years. In various embodiments, the methods and compositions provide for potent action and long duration of action, with infrequent intravitreal injections of a small volume.

SLEEP DIETARY SUPPLEMENT
20230054630 · 2023-02-23 ·

The present invention is directed to improving sleep quality and supporting recovery of joints, ligaments, and tendons with collagen peptides and dietary ingredients that support sleep quality. The supplement composition of the present invention comprises collagen, GABA, L-Theanine, 5-HTP, L-Tryptophan, and Magnesium. The recovery from exercise and physical activity is improved using this combination of components.

SLEEP DIETARY SUPPLEMENT
20230054630 · 2023-02-23 ·

The present invention is directed to improving sleep quality and supporting recovery of joints, ligaments, and tendons with collagen peptides and dietary ingredients that support sleep quality. The supplement composition of the present invention comprises collagen, GABA, L-Theanine, 5-HTP, L-Tryptophan, and Magnesium. The recovery from exercise and physical activity is improved using this combination of components.

SLEEP DIETARY SUPPLEMENT
20230054630 · 2023-02-23 ·

The present invention is directed to improving sleep quality and supporting recovery of joints, ligaments, and tendons with collagen peptides and dietary ingredients that support sleep quality. The supplement composition of the present invention comprises collagen, GABA, L-Theanine, 5-HTP, L-Tryptophan, and Magnesium. The recovery from exercise and physical activity is improved using this combination of components.

MICROBIOME INTERVENTIONS

The present disclosure relates to compositions comprising a range of ingredients suitable for use in adjusting and/or treating a companion animal such as a canid (e.g. a dog) or a feline (e.g. a cat) and their microbiomes, monitoring tools, and diagnostic methods for determining the health of a companion animal and their microbiome.

MICROBIOME INTERVENTIONS

The present disclosure relates to compositions comprising a range of ingredients suitable for use in adjusting and/or treating a companion animal such as a canid (e.g. a dog) or a feline (e.g. a cat) and their microbiomes, monitoring tools, and diagnostic methods for determining the health of a companion animal and their microbiome.

Programmable liquid, gel and biohybrid compartments and methods of use

Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase separation point of a first component, and maintaining stimulation at the phase separation point to form a coacervate domain of the first component within each of the droplets to form the liquid coacervate particles. The self-assembled nano, meso, micro and macro liquid coacervate particles and related coated substrates can have utility in drug delivery, bioanalytical systems, controlled cell culture, tissue engineering, biomanufacturing and drug discovery.

Biocompatible hydrogel compositions and uses thereof

Provided herein are biocompatible and/or biodegradable hydrogel compositions comprising native collagen and chondroitin sulfate, the collagen and chondroitin sulfate being chemically cross-linked thereby forming a matrix. The native collagen may comprise recombinant human collagen type I (rHCI), recombinant human collagen type III (rHCIII), or a combination thereof, for example. Methods and uses thereof for regeneration or repair of tissue, improvement of tissue function, mechanical stabilization of tissue, prevention of tissue damage, or prevention of tissue loss of function are described, particularly with respect to cardiac tissue and myocardial infarction events.

Biocompatible hydrogel compositions and uses thereof

Provided herein are biocompatible and/or biodegradable hydrogel compositions comprising native collagen and chondroitin sulfate, the collagen and chondroitin sulfate being chemically cross-linked thereby forming a matrix. The native collagen may comprise recombinant human collagen type I (rHCI), recombinant human collagen type III (rHCIII), or a combination thereof, for example. Methods and uses thereof for regeneration or repair of tissue, improvement of tissue function, mechanical stabilization of tissue, prevention of tissue damage, or prevention of tissue loss of function are described, particularly with respect to cardiac tissue and myocardial infarction events.