A NEMS readout system includes a sensor array comprising a plurality of sensors. Each sensor of the plurality of sensors including a resonator with frequency characteristics different from the resonator of each other sensor of the plurality of sensors. A readout signal indicative of a plurality of output signals is collected from the sensor array. Each output signal of the plurality of output signals corresponding to one of the plurality of sensors. An analysis of the plurality of output signals is performed to identify a plurality of resonant frequencies and to detect a frequency shift associated with at least one of the plurality of resonant frequencies.

The invention relates to a mass spectrometer, a mass spectrometry method and a detection system. The mass spectrometer includes a vacuum chamber having a working pressure being 0.1 Pa≤P≤10 Pa; a linear ion trap, arranged in the vacuum chamber, wherein a field radius r of the linear ion trap is r≤5 mm; and a power supply, configured to provide a radio-frequency voltage for the linear ion trap, a frequency f of the radio-frequency voltage being 2 MHz≤f≤10 MHz. Because a vacuum level is relatively low, this vacuum condition may be realized by selecting a roughing pump for evacuating; and compared with a combined pump unit which is generally selected by a traditional mass spectrometer using the linear ion trap and is composed of a turbo molecular pump and a roughing pump, the roughing pump has a lower pumping speed, smaller size and lower manufacturing cost.

A low power mass spectrometer assembly includes at least an ionization component, an electrostatic analyzer, a lens assembly, a magnet assembly and at least one detector located in a same plane as the entrance to the magnet assembly for detecting the deflected sample ions and/or fragments of sample ions, including ions or ion fragments indicative of the Vitamin D metabolite within the sample.

A method for analyzing biological samples using mass spectrometry or ion mobility spectrometry that includes producing gas-phase ions and neutrals from the sample in a proximity of the sample; transferring the produced ions from the sample to a distance via a flexible or re-configurable ion transfer device such that the flexible or re-configurable ion transfer device includes a plurality of electrodes configured to be flexible or flexibly connected to each other, and the ion transfer device is configured to be flexible while transferring the ions to allow the ion transfer device to form one or more curvatures; and separating the produced ions with a mass spectrometer or a mobility analyzer located at the distance to provide spectrometric results.

A vacuum chamber 11 for forming a vacuum space has two side walls opposite to each other across an ion beam axis extending within the vacuum space. One of those side walls is openable and closeable. An ion optical element 21 is placed on a base 33, which is located on the bottom surface of the vacuum chamber. A fixation band 213 fixes the ion optical element on the base by holding the element between the base and the fixation band so as to press the element onto the base. A band-catching portion 10d, located on an inside face of a side wall of the vacuum chamber on the opposite side from the openable-and-closeable side wall, catches one end of the fixation band. A band-fixing portion 214, located on the base on the side where the openable-and-closeable side wall is present, fixes the other end of the fixation band to the base.

The invention generally relates to systems and methods for conducting reactions and screening for reaction products.

The invention generally relates to systems and methods for performing multiple precursor, neutral loss and product ion scans in a single ion trap. In certain aspects, the invention provides systems including a mass spectrometer having a single ion trap, and a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply at least one of the following ion scans to a single ion population in the single ion trap: multiple precursor ion scans, a plurality of segmented neutral loss scans, or multiple simultaneous neutral loss scans.

The invention provides a cycloidal mass spectrometer and a method for adjusting resolution thereof. The spectrometer comprises a set of magnets, providing a magnetic field; two sets of electrode arrays, opposing to each other parallelly, each set of the electrode array including a plurality of strip electrodes arranged parallelly; at least one DC power supply, providing DC voltages to each set of the electrode array to form a DC electric field, the direction of the electric field being perpendicular to the direction of the magnetic field, and the electric field and the magnetic field superimposed on each other to form an electric-magnetic cross-field; an ion injection unit, configured to inject ions into the electric-magnetic cross-field. Said ions travel along a cycloidal trajectory in the electric-magnetic cross-field, in which the magnetic field intensity and the electric field intensity decrease simultaneously within at least part of the region in said cycloidal trajectory.

A smoke alarm may include at least one sensor head including a miniature mass spectrometer; a microcontroller unit configured to receive data from each of the at least one sensor head; and at least one of a photoelectric detector, or ionization detector. Further, the smoke alarm may be capable of determining categories of smoke and delivering discrete alerts accordingly.

The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.