The present discovery pertains to the discovery of certain amphiphilic compounds that may be useful for the management of sebum secretion in subjects with acne, oily skin, or seborrheic dermatitis. These compounds are 1-dialkylphosphorylalkanes with the longest alkyl group being seven or more carbons. Preferably, a compound is dissolved in a dermatologically acceptable vehicle, and delivered to the skin in a solution, gel, lotion, cream, or ointment. The method of application may be with the surface of the finger, or via an applicator. The decrease is sebum secretion in certain subjects may result in skin conditions that enhance cosmetic appearance and ameliorate skin disorders.

The present invention discloses a multifunctional temperature self-regulating multilayer film, from outside to inside comprising at least: a carrier layer (1) loaded with functional material, and a thermal-insulation layer (2) directly contacted with the skin (4); wherein the carrier layer (1) loaded with functional material has a sealed cavity sealed with a flexible water-impermeable material, the sealed cavity is at least loaded with a refrigerating or heat-generating chemical material (11); wherein thermal-insulation layer (2) is made of a material having waterproof and thermal-insulation properties. The present multilayer film can be manufactured into a face mask or eye mask for use on facial skin.

A method for applying an emollient fluid to the skin includes cooling an emollient fluid and applying the cooled fluid to the skin. The emollient fluid may be made from a powdered plant product mixed into an aqueous medium. The fluid may be cooled to form a solid which is applied to the skin. Optionally, the solid is formed on an applicator which serves as a handle for the user. A kit which includes a mold, an applicator and a supply of emollient product is provided. The powdered plant product may be made from a powdered plant, powdered fruit or powdered extract of any one or more of pineapple, pumpkin, rice, banana, oats, cucumber, strawberry, lemon peel, watermelon, guava, mango avocado, tomato, blueberries, pomegranate, green tea (matcha), spirulina, dragon fruit, and beet.

Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.

The present invention relates to a formulation comprising an endothermic cooling agent selected from the group consisting of xylitol, sorbitol, mannitol and erythritol having a heat of enthalpy between −10 cal/g and −100 cal/g, and one or more active agents wherein the endothermic agent is present in the formulation at an amount less than 10% w/w.

Use as a cooling agent of a compound of general formula (I)

##STR00001##

in which: R.sup.1 and R.sup.2 are chosen independently of each other as a hydrogen atom or a C.sub.1-C.sub.6-alkyl group; and X represents ═O, —OAc, —O—C.sub.1-C.sub.6-alkyl, —N—OH or —OH.

A cooling agent composition contains a 2,2,6-trimethylcyclohexanecarboxylic acid derivative represented by the following general formula (1). The symbol * represents an asymmetric carbon atom. X represents NH, N(ZAr.sup.2), O or S, Z represents a single bond or an alkylene group having 1 to 3 carbon atoms which may have a substituent, Ar.sup.2 represents an aryl group having 6 to 20 carbon atoms which may have a substituent or an aromatic heterocyclic group having 2 to 15 carbon atoms which may have a substituent. Y each independently represents a methylene group which may have a substituent, and n represents an integer of 0 to 3. Ar.sup.1 represents an aryl group having 6 to 20 carbon atoms which may have a substituent or an aromatic heterocyclic group having 2 to 15 carbon atoms which may have a substituent. ##STR00001##

Compositions, methods, and kits for cleansing, moisturizing, soothing, cooling, such as those, for example, that may be used to cleanse, moisturize, soothe, and cool the body or portions thereof.