A61K2800/244

CORE-SHELL PCM MICROCAPSULE HAVING AUTOMATIC TEMPERATURE CONTROL FUNCTION AND COOLING COSMETIC COMPOSITION FOR EXTERNAL SKIN INCLUDING THE SAME

Provided are preparation of a PCM microcapsule in the form of a core-shell having an excellent heat absorption function by using a temperature-controllable phase change material (PCM) as a core material and a biodegradable polymer material as a shell material, and a cooling cosmetic composition for external skin capable of exhibiting a prevention effect of thermal aging using the same. The core-shell PCM microcapsule having an automatic temperature control function according to the present invention is prepared by dissolving a shell material and a single or mixed PCM in a solvent to produce an oil phase polymer solution, dissolving an aqueous polymer to produce an external continuous phase, emulsifying the oil phase polymer solution and the external continuous phase, and removing the external continuous phase and the solvent and carrying out drying.

Absorbent article

An absorbent article including at least a topsheet layer and a backsheet layer, each layer having a body facing surface and a garment facing surface, and longitudinal and transversal edges, the article having a longitudinal front portion, a longitudinal back portion and a crotch portion located between the front and the back portion, the article includes a first zone of microencapsulated phase change material on a surface of a layer of the article, and wherein the first zone has a non-linear boundary in at least the transversal direction of the article.

SOLUBILIZATION OF POORLY SOLUBLE COOLING SUBSTANCES
20210267864 · 2021-09-02 ·

The present invention relates to a cooling composition for producing cooling particles comprising a solvent component and dissolved therein (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-cyclohexane-carboxamide. The present invention further relates to cooling particles comprising a cooling composition according to the invention, oral preparations comprising cooling particles, new uses of cooling particles, a process for the production of cooling particles as well as the use of a solvent component for dissolving cooling agents.

Pyridinyl cyclohexanecarboxamide cooling compounds

A method of providing a cooling effect to a product includes the incorporation into the product of at least one compound of the formula I ##STR00001##
in which m is a number between 0 and 2, X, Y and Z are selected independently from the group consisting of H, halogen, OH, Me, Et, MeO and EtO, and R.sup.1, R.sup.2 and R.sup.3 together comprise at least 6 carbons, selected such that (a) (i) R.sup.1 is selected from the group consisting of H, Me, Et, isopropyl and C.sub.4-C.sub.5 branched alkyl; and (ii) R.sup.2 and R.sup.3 are independently selected from the group consisting of Me, Et, isopropyl and C.sub.4-branched alkyl; or (b) any two or all of R.sup.1, R.sup.2 and R.sup.3 together form a monocyclic, bicyclic or tricyclic radical having up to 10 carbons. The compounds confer substantial cooling effects on compositions applied to the skin or taken orally, such as toothpastes, mouthwashes, foodstuffs, beverages, confectionery, tobacco products, skin creams and ointments.

Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof

The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.

ABSORBENT ARTICLE

The absorbent article comprises at least a topsheet layer and a backsheet layer, each layer having a body facing surface and a garment facing surface, and longitudinal and transversal edges, the article having a longitudinal front portion, a longitudinal back portion and a crotch portion located between the front and the back portion. The article comprises a first and a second zone of microencapsulated phase change material on a surface of a layer of the article. The first and second zones are selected form zones having different microencapsulated phase change materials, different concentrations of a microencapsulated phase change material or comprise microencapsulated phase change material having different phase change temperature intervals.

NATURE-BASED COMPOSITIONS, DISPENSING SYSTEMS AND METHODS FOR PROVIDING SENSORIAL AND AESTHETIC BENEFITS TO ACNE PRONE SKIN
20210196591 · 2021-07-01 · ·

A cosmetic composition includes at least one beta hydroxy acid selected from -n-octanoylsalicylic acid, salicylate, sodium salicylate, willow extract, beta hydroxybutanoic acid, tropic acid, and trethocanic acid present in a hydroalcoholic gel dispersion that includes at least one C2-C5 alcohol, (ii a blend of at least two powders selected from at least one inorganic powder and at least one nature-based organic powder, and (iii) at least one nature-based polymer that excludes synthetic organic polymers. The cosmetic composition may be dispensed using a porous applicator and is applied as an on-the-go skin refresher that is especially good for acne-prone skin. The cosmetic composition can be used throughout the day to control shine and minimize skin imperfections and discourage acne and is suitable for use alone or over or under make up.

Azeotrope-like compositions of 1,1,1,2-tetrafluoropropene and 1,1,1,2-tetrafluoroethane

Provided are azeotrope-like compositions consisting essentially of 1,1,1,2-tetrafluoropropene and 1,1,1,2-tetrafluoroethane and uses thereof, including use in refrigerant compositions, refrigeration systems, blowing agent compositions, and aerosol propellants.

COATING COMPOSITION AND ELASTOMERIC ARTICLE CONTAINING THE SAME
20210147649 · 2021-05-20 ·

A coating composition, an elastomeric article having the coating composition and a process for making coated elastomeric articles are disclosed in the present invention. The coating composition comprises 0.5% to 11% by weight/volume of at least one cooling agent; 0.5% to 11% by weight/volume of at least one non-ionic surfactant; and water, wherein rest of the coating composition is made of water. The coated elastomeric articles prepared according to the present invention improve user's sensory experience of wearing the elastomeric articles for long durations without varying the user's hand temperature or limiting mobility of the user's hand.