Disclosed herein is a topical composition that delivers advanced environmental protection to the skin, brightens the complexion of the skin, and delivers anti-aging benefits to the skin. The topical composition includes a vitamin C source, a copper source, one or more cannabinoid components, and sodium hyaluronate. Also disclosed herein are methods of administering the topical compositions.

The present invention relates to non-toxic consumable compositions and formulations comprising chelator and base having synergistic effects on microbial metabolism and/or growth and/orpathogenic effectors and their use to promote and maintain health in mammals. The current invention also relates to non-toxic consumable compositions comprising more than one chelator and/or more than one base. The present invention further relates to methods for selecting said chelator and base composition and methods for detecting conditions in which selected compositions may be used. The present invention relates to the synergistic compositions and methods of their use for maintaing health, promoting health and treating diseases.

The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent.

The invention relates to a composition for use in reducing hair loss and/or increasing regrowth of hair in a human subject comprising minoxidil, either a 5α-reductase inhibitor or an androgen receptor antagonist, and a prostaglandin analog. In one embodiment, the composition comprises minoxidil, a 5α-reductase inhibitor, and a prostaglandin analog, wherein the 5α-reductase inhibitor is finasteride. In another embodiment, the prostaglandin analog is latanoprost. In yet another embodiment, the composition is for topical application to a scalp. The invention also relates to the use of such a composition to reduce hair loss and/or increase regrowth of hair in a human subject.

The present disclosure relates to broad spectrum sunscreen compositions, and to methods for using broad spectrum sunscreen compositions to protect the skin from UV radiation. In at least one aspect the sunscreen comprises: a metal oxide (e.g., zinc oxide) one or more SPF active ingredients (e.g., octinoxate and/or octisalate) and one or more SPF enhancement ingredients (e.g., a photo stabilizer (e.g., butyloctyl salicylate and/or ethylhexyl methoxycrylene) and/or an antioxidant (e.g., a plant extract) (e.g., pongamia pinnata extract).

The present disclosure relates to hair-treatment compositions, typically in the form of an oil-in-water emulsion, comprising: (a) one or more monosaccharides with amine group(s); (b) one or more polysaccharides with amine group(s); wherein (a) and (b) are solubilized in an aqueous phase of the oil-in-water emulsion; (c) one or more oils; (d) one or more nonionic emulsifiers; and (e) water. The compositions strengthen hair fibers and provide additional cosmetic improvements to the hair such as conditioning, detangling, softness, suppleness, moisturizing, and manageability. Methods of treating hair with the compositions are also described. The methods include applying the composition to wet or damp hair, drying the hair (for example, with a blow dryer) and treating the hair with heat (for example, with a hot iron).

A crosslinkable coating composition comprising: ingredient A that has at least two protons that can be activated to form a Michael carbanion donor; ingredient B that functions as a Michael acceptor having at least two ethylenically unsaturated functionalities each activated by an electron-withdrawing group; and a dormant carbamate initiator of Formula (1) ##STR00001##
wherein R.sub.1 and R.sub.2 can be independently selected from hydrogen, a linear or branched substituted or unsubstituted alkyl group having 1 to 22 carbon atoms; 1 to 8 carbon atoms; and A.sup.n+ is a cationic species or polymer and n is an integer equal or greater than 1 with the proviso that A.sup.n+ is not an acidic hydrogen; and optionally further comprising ammonium carbamate (H.sub.2NR.sub.1R.sub.2.sup.+−OC═ONR.sub.1R.sub.2). The crosslinkable coating composition can be used for a variety of coating applications including nail coating compositions.

This disclosure relates to topical formulations (including scalp essences, scalp cleansers, and scalp masks) for balancing the scalp microbiome and uses thereof to improve hair health or scalp health or treat or prevent hair loss.

A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myo-inositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.