A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.

A cosmetic composition including a water phase, the water phase comprising solubilized 4-hydroxyacetophenone with niacinamide, wherein the weight ratio of niacinamide to 4-hydroxyacetophenone in the water phase is greater than 3.0.

This invention illustrates a composition which has a high antioxidant power in cosmetic products. The composition includes a combination of two critical ingredients, originating from two natural superfood products: olive and kale. This current technology utilizes the sprout of kale, instead of the whole plant, as one ingredient. In the perspective of olive extract, it is either in the form of a concentrated liquid syrup of olive tree and leaf, which is enriched with natural polyphenols, especially with high content of hydroxytyrosol, or in the form of pure liquid hydroxytyrosol. An enhanced antioxidant power is observed when incorporating the kale sprouts together with the olive leaf extract.

The present disclosure relates generally to antioxidant compositions and their uses in personal care products. More specifically, the disclosure provides diethylhexyl syringylidene malonate-containing compositions for use in sunscreen or non-sun-screen formulations. Also provided are diethylhexyl syringylidene malonate-containing compositions and methods for treating and/or preventing photodamage caused by long UVA and/or visible light.

The present disclosure provides compounds and compositions which may be used to augment, supplement and/or replace the products of certain UV sensitive/dependent processes. In particular, the disclosure provides sunscreen compositions which avoid problems associated with prior art sunscreen compositions which inhibit the natural progression of certain in vivo sunlight/UV dependent processes including processes which result in Nitric Oxide/Vitamin D production in the skin.

The disclosure provides personal care compositions that comprise a moisturizing agent of formula (I) wherein n is an integer from 2 to 5, R.sup.1 is independently H or C.sub.1-C.sub.3 alkyl and R.sup.2 is an unsubstituted linear or branched C.sub.1-C.sub.6 alkyl, at least one additional moisturizing agent and a cosmetically acceptable vehicle. In particular, the compound of formula (I) is diglycolamine acetamide. The compositions generally improve moisturization of skin and hair. ##STR00001##

Provided herein is a personal care composition that can exhibit an increased vapor release while maintaining physical stability and texture. The personal care composition can have from about 35% to about 90% petrolatum, an additional microcrystalline wax having a needle penetration at 25° C. of from about 35 to about 75 dmm, from about 1% to about 8% of a gelling agent mixture, and from about 20% to about 50% of an olfactory composition, all by weight of the composition.

A method of identifying or evaluating synergistic combinations of actives such as skin-care actives that improve the metabolism of a cell and provides an advantage over using the actives alone. The method includes contacting cells with test agents, alone and in combination, and determining a response of the cells to the test agent(s), wherein the response corresponds to a change in a metabolic indicator associated with glycolysis and a change in a metabolic indicator associated with oxidative phosphylation.

The invention relates to a composition comprising 2% to 5% minoxidil, 0.01% to 15% finasteride and 0.01% to 15% of a prostaglandin analogue. In one embodiment, the prostaglandin analogue is latanoprost. In a preferred embodiment, the composition comprises 5% minoxidil, 0.1% finasteride and 0.03% latanoprost. The invention also relates to the use of the said composition to reduce hair loss and/or increase regrowth of hair in a human subject.

Suggested is a preservative mixture with improved solubility comprising or consisting of (a) 4-isopropyl-3-methylphenol; (b) at least one hydrophilic solvent having a log P.sub.o/w of 1.2 or below; and (c) at least one lipophilic solvent having a log P.sub.o/w of above 1.2.