This invention provides novel injectable compositions comprising botulinum toxin that may be administered to a subject for various therapeutic, aesthetic and/or cosmetic purposes. The injectable compositions contemplated by the invention exhibit one or more advantages over conventional botulinum toxin formulations, including reduced antigenicity, a reduced tendency to undergo unwanted localized diffusion following injection, increased duration of clinical efficacy or enhanced potency relative, faster onset of clinical efficacy, and/or improved stability.

An object is to provide a new cosmetic composition that can prevent or reduce skin “photoaging” caused by blue light. As a solution, a cosmetic composition is provided, which is characterized in that it contains: (a) one or more types of alkyl phosphate esters selected from alkyl phosphate esters having alkyl groups with 12 to 36 carbon atoms; (b) one or more types of substances selected from basic amino acids and organic bases; (c) water; and (d) lutein.

A water-in-oil emulsion cosmetic, in which an ultraviolet scattering agent is uniformly dispersed in a base, an excellent ultraviolet protective effect is stably imparted, and whitishness is suppressed. A water-in-oil emulsion cosmetic is described, comprising the following components (a), (b), (c), and (d): (a) titanium dioxide surface-treated with a fatty acid and/or an alkylalkoxysilane; (b) an amphiphilic substance which is solid at normal temperature; (c) a linear silicone oil; and (d) a volatile hydrocarbon oil.

Applicants have identified a critical skin benefit package that can be used in liquid alcohol sanitizing compositions that provides lower amounts of skin conditioners in combination with a specific ratio of different emollients that provide improved skin health with chronic repeated use. The package also provides improved skin feel with without a tacky residue upon drying.

Oral care compositions comprising a neutral amino acid and stannous ion source are provided for promoting Gum Health of a user.

The application relates to a dispersant composition, including: at least one alkyl polyglucoside; and a diester of formula (B)

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R and R′, being the same or different, represent an alkyl group, linear or branched, including from 1 to 10 carbon atoms, and Z is a linear or branched group of formula —(C.sub.nH.sub.2n)—, n being an integer from 1 to 10. The dispersant composition is such that the mass ratio of the proportion by weight of alkyl polyglycoside relative to the proportion by weight of diester of formula (B) is from 7.4 to 18.0.

Oral care compositions comprising an amino acid and stannous ion source, especially in the absence of zinc ion source, are provided for promoting Gum Health of a user.

An object of the present invention is to provide an aerosol product for forming a warming cream composition which is capable of achieving excellent dispersion stability of hydration exothermic substance powder and of easily forming a warming cream composition having a sufficient warming effect. The aerosol product of the present invention includes a double structure container provided with a discharging mechanism for simultaneously discharging contents filled in the two liquid concentrate filling spaces. The propellant filling space is filled with a propellant composed of compressed gas. The first liquid concentrate filling space is filled with a composition, which includes hydration exothermic substance powder dispersed in a liquid medium containing a polyhydric alcohol and a higher alcohol and having a viscosity (at 20° C.) of 1000 to 10000 mPa.Math.s, containing 10 to 40% by mass of the hydration exothermic substance powder, and 0.05 to 20% by mass of the higher alcohol, and having a viscosity (at 20° C.) of 1000 to 125000 mPa.Math.s. The second liquid concentrate filling space is filled with a composition containing water and 0.1 to 10% by mass of a viscosity modifier.

A cream formulation or topical use made of a mixture of naturally occurring biologically active phytochemical compounds that possess a variety of beneficial animal and human health effects. An extract from an aqueous extraction process or other active ingredients could be used in the cream formulation. The present invention generally provides for the preparation of cream formulations containing active ingredients that contain individually, or in combination, an analgesic, natural product extracts, or a protein or proteins from the tripartite motif family of proteins (TRIM). The analgesic will provide mitigation of pain during the healing process.

A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods include addition of an effective amount of such compounds to a cosmetic, toiletry or pharmaceutical formulation. Compositions further including alkanediols and/or solubilizing agents in blends with hydroxamic acid are also described.