A method for producing a protein composition containing a protein (A), a radical scavenger (RS), and at least one hydrogen-bond-formable compound (HC) selected from the group consisting of amino acids, peptides, and proteins other than the protein (A). The method including a sterilization step of radiosterilizing an unsterilized protein composition, wherein the unsterilized protein composition contains the protein (A), the radical scavenger (RS), and the hydrogen-bond-formable compound (HC), the protein (A) contains at least one functional group selected from the group consisting of sulfide, amide, hydroxyl, amino, and carboxyl groups, the hydrogen-bond-formable compound (HC) contains at least one functional group selected from the group consisting of sulfide, amide, hydroxyl, amino, and carboxyl groups, the at least one functional group in the protein (A) is capable of binding to the at least one functional group in the hydrogen-bond-formable compound (HC) via a hydrogen bond.

According to some aspects, there is provided a method of selectively inactivating viruses through acoustic resonance by non-ionizing gigahertz electromagnetic radiation. In some implementations, there is provided an apparatus comprising a power processing unit; a microwave source; an antenna; a control unit; wherein the spatial and temporal characteristics of the electromagnetic field are optimized to maximize viral inactivation at the target location while minimizing overall radiation exposure. Methods of delivering high peak energy into the virus structure with minimal total average power are also provided.

An implantable article comprising a dissolvable sponge derived from a mixture of chitosan, a first cellulosic polysaccharide and a second cellulosic polysaccharide. The cellulosic polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.

Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.

An injectable depot composition suitable for forming an in situ intramuscular implant is provided. The composition includes sterile biodegradable thermoplastic polymer of polylactic acid (PLA), solvent for the PLA, and drug. After administration to a subject, a corresponding implant administers 0.1-2 milligrams of nonsteroidal aromatase inhibitor every day throughout a dosing period of about six months to about one year. The composition is used to treat subjects in need thereof.

A therapeutic endotracheal tube assembly is provided for insertion into a patient's trachea to ventilate, to maintain patency of the patient's airway, and to deliver therapeutic electromagnetic radiation (EMR) to the patient. The therapeutic endotracheal tube assembly has an endotracheal tube and an EMR delivery system. The EMR delivery system has an EMR source for emitting non-ultraviolet, therapeutic EMR having intensity sufficient to activate desired therapeutic properties within the patient and an EMR conduction line conducive to the propagation of EMR from the EMR source along the endotracheal tube. The EMR conduction line is removably insertable into the endotracheal tube. The therapeutic endotracheal tube assembly may be custom made or may be constructed by retrofitting a removably insertable EMR delivery system to an existing endotracheal tube.

An earphone storage device includes a charging storage box. A top cover that can be closed is provided on the charging storage box. A storage tank and a cleaning device are provided in the charging storage box, and a charging assembly is provided at the bottom of the storage tank. The cleaning device includes a dust removal assembly, a disinfection assembly and a sterilization assembly. A rotating shaft and a rotating motor are rotatably provided at the center of the top cover. The rotating motor is connected with the rotating shaft, the rotating shaft is connected with a rotating disc, and the rotating disc is provided with three mounting grooves. The dust removal assembly, the disinfection assembly and the sterilization assembly are respectively fixed in the three mounting grooves. When the top cover is closed, the storage tank is located directly below a rotation track of the mounting groove.

A system/method for producing a substance attractive to one or more species of insect characterised by: housing a population of live insects; providing any combination of nutrients, food or water to the live insects; removing organic matter from the population; and sterilizing the removed organic matter.

Disclosed herein is a method for validation of continuous viral clearance comprising the steps of providing a probe to be validated, spiking the probe in a valid manner, performing viral clearance, sampling the spiked probe and analyzing the sample of the spiked probe of step d).

Methods and apparatus provide therapeutic electromagnetic radiation (EMR) for inactivating infectious agents in, on or around a catheter residing in a patient's body cavity and/or for enhancing healthy cell growth. The method comprises transmitting non-ultraviolet therapeutic EMR substantially axially along an optical element in a lumen of the catheter body and/or the catheter body. Through delivery of the therapeutic EMR to particular infected areas and/or areas requiring tissue healing. The methods and apparatus of the present disclosure inactivate the major sources of infection in, on, and around catheters and/or enhance healthy cell growth around catheters.