A method of making an electron beam irradiated osteoinductive implant is provided. The method comprises exposing an osteoinductive implant containing demineralized bone matrix (DBM) fibers to electron beam radiation at a dose of from about 10 kilograys to 100 kilograys for a period of time. The electron beam irradiation reduces microorganisms in the osteoinductive implant, and the electron beam irradiated osteoinductive implant retains osteoinductive properties. Methods of implantation and an irradiated osteoinductive implant are also disclosed.

A collimator to control and/or focus radiation originating from an electron beam source, comprising at least a first absorber comprising a first side configured to allow the beam entry and a second side opposite to the first side; and at least one recess in the first absorber wherein a first contour of the recess at the first side is larger than a second contour of the recess at the second side. Further, a to control and/or focus radiation originating from an electron beam source, comprising the steps of providing at least a first collimator according to any of the preceding collimator claims; providing a product to be sterilized; arranging or assembling the collimator with the respect to the product so that the collimated electrons are oriented towards at least one part of the product to be sterilized and electrons are absorbed towards at least another part of the product that to be not harmed by those

A method may be provided for inactivating biologically active components in a liquid using low-energy electrons generated by an electron source, the electrons having an acceleration voltage of 25 keV to 300 keV. The method comprises the following steps: a) filling a vessel with a liquid volume; b) applying low-energy electrons to a first partial volume of the liquid filled into the vessel, wherein the first partial volume is a maximum of 10% of the liquid volume in the vessel; c) mixing the first partial volume of the liquid, applied with the low-energy electrons, to the second partial liquid volume in the vessel, which has not been applied with low-energy electrons; d) repeating steps b) and c) several times.

Terminally sterilized demineralized bone material (DBM) and systems and methods for protecting DBM against damage caused by terminal irradiation are described. A method includes providing the DBM, which includes at least a collagen matrix and natural, non-collagenous protein. The DBM is soaked in a mixture of glycerol and a solvent to remove and replace water in the collagen matrix of the DBM. The DBM is dried, after soaking, to form a protected DBM.

To provide an endoscope cap with a raising base or the like which is easily attached and detached to and from a distal end of an endoscope.

The endoscope cap includes: a cover that is attachable and detachable to and from a distal end of an insertion portion of an endoscope including a lever which is rotatably provided at the distal end of the insertion portion of the endoscope and a rotating portion which rotates the lever; and a raising base that has a lever connection portion connected to the lever and is rotatably provided inside the cover, and the endoscope cap is supplied in the state of being enclosed in an individual packaging member.

A surface treatment method and a surface treatment device 2 for a resin vessel 1 forms a coating or performs surface modification on the surface of the resin vessel 1. In a sterilized environment as well as an environment with a pressure equal to or higher than the atmospheric pressure, a material for the coating or the surface modification is attached to at least one of an inner surface and an outer surface of the resin vessel 1, and the resin vessel 1, to which the material is attached, is irradiated with an electron beam to perform the coating or the surface modification. It is possible to form the coating or perform the surface modification on the resin vessel at a high speed.

A method of making a ready-to-use catheter assembly is provided, which can be immediately used by a patient. The ready-to-use catheter assembly ensures that the catheter does not suffer from a loss of quality during its shelf life and a wetting medium are provided. The method comprises: placing a catheter with an inactivated hydrophilic outer surface at least along its insertable length and a wetting medium in a catheter package; treating the catheter package with the catheter and the wetting medium with electro-magnetic and/or particle radiation while at least initially the hydrophilic outer surface at least along the insertable length of the catheter remains inactivated; and activating the hydrophilic outer surface at least along the insertable length of the catheter with the wetting medium during and/or after the radiation treatment and wherein the wetting medium decreases in viscosity when submitted to electro-magnetic and/or particle radiation.

A magnetic apparatus and a method of operating the magnetic apparatus can include a scanning electromagnet that redirects a beam of charged particles, a vacuum chamber that prevents the atmosphere from interfering with the charged particles, and, a parallelizing permanent magnet array for parallelizing the beam of charged particles. The parallelizing permanent magnet array can be located proximate to a target comprising a Bremsstrahlung target or an object that is being irradiated. The magnetic field of the scanning electromagnet can be variable to produce all angles necessary to sweep the beam of charged particles across the target and the parallelizing permanent magnet array can be configured from a magnetic material that does not require an electric current.

The present invention relates to a medical device to be applied to a body of a human or animal being. The medical device comprises a contact surface to contact the body of the human or animal being when the medical device is applied to the body of the human or animal being. The contact surface is covered with a soluble surface sealing. The surface sealing is composed of an organic compound.

A fluid filtration system is shown. The fluid filtration system utilizes a one-piece or multiple piece containers having a plurality of radiation-transmissible media adapted to receive light, such as ultraviolet light, white light or other wavelength light. The radiation-transmissible media are situated in the container and at least one or a plurality of radiation sources, such as ultraviolet lamps, are situated in an array in proximity to the radiation-transmissible media. The radiation-transmissible media interrupts the flow and velocity of the fluid stream passing through the container to extend the duration of radiation for any contaminants and also provide enlarged surface areas for the contaminants to be received and ultimately exposed to the radiation. In one example, the radiation-transmissible media may be tubular or spherical sections that are hollow or solid and made of quartz.