A digital representation of an object is formed. The properties of incident electrons are calculated from a parameterized source model and the irradiation of the object is simulated. The particle-matter interactions for a material of the object are calculated. The amount of absorbed dose at locations at the object is calculated. The digital representation of the object is modified in response to an input from a user and the modified digital representation of the object is displayed.

A preform is sterilized by a preform sterilizer. The preform is blow-molded by a blow-molding device to manufacture a container. Next, the container is filled with a culture medium by a filling device without sterilizing the container by a container sterilizer, and the container is plugged by a plugging device. Thereafter, it is verified how much microorganism survive or propagate in the culture medium in the container. A degree of sterilization in the container sterilizer is adjusted on the basis of a verification result.

A system includes a sensor applicator, a sensor control device arranged within the sensor applicator and including an electronics housing and a sensor extending from a bottom of the electronics housing, and a cap coupled to one of the sensor applicator and the sensor control device, wherein the cap is removable prior to deploying the sensor control device from the sensor applicator.

A surface decontamination device (1) for decontaminating outer packagings (2) which contain pre-sterilised consumer goods and have a circumferential collar (3) prior to transfer into an insulator includes a conveyor for conveying the outer packagings (2) in a conveying direction (F) along a conveying path from an inlet side to an outlet side of the device (1). The conveying path passes through a decontamination chamber (5) between the inlet side and outlet side. An irradiation source (6) is associated with the chamber (5) for irradiating the outer packagings (2) conveyed through the chamber (5). The conveying path passes through at least one lock chamber (8) arranged between the inlet side and outlet side, adjacent to the chamber (5) and having an inlet and an outlet, the inlet and outlet being able to be opened and closed by a closer. The conveyor includes a suspended transport unit (7) in the chamber (5) for suspended transport of the outer packagings (2) on the circumferential collar (3) thereof, wherein a lifting unit (11, 15) for automatic, vertical adjustment of the outer packagings (2) relative to the suspended transport unit (7) is arranged in the lock chamber (8, 14).

A method of disinfecting personal protective masks and mask filters, includes the step of applying sterilizing ionizing radiation to the personal protective mask while it is disposed in an electromagnetically shielded container.

A magnetic apparatus and a method of operating the magnetic apparatus can include a scanning electromagnet that redirects a beam of charged particles, a vacuum chamber that prevents the atmosphere from interfering with the charged particles, and, a parallelizing permanent magnet array for parallelizing the beam of charged particles. The parallelizing permanent magnet array can be located proximate to a target comprising a Bremsstrahlung target or an object that is being irradiated. The magnetic field of the scanning electromagnet can be variable to produce all angles necessary to sweep the beam of charged particles across the target and the parallelizing permanent magnet array can be configured from a magnetic material that does not require an electric current.

A system and method are provided for packaging and sterilizing analyte sensors. The packaging system provides a structure for securing the analyte sensors in a fixed position and fixed orientation within the package.

Aspects of the disclosure relate to “wet” transcatheter prosthetic heart valve or other implant packaging and assemblies in which a prosthetic heart valve or other implant is loaded into a first portion of a delivery device and positioned within a container in which sterilizing fluid is retained to sterilize inside of the container as well as provide moisture to prevent the implant from drying out. The disclosure also relates to methods of sterilizing the disclosed assemblies. Some disclosed methods include at least two sterilizing steps and adjustment of a shaft seal or formation of multiple seals maintaining sterilizing fluid within the container so that areas underneath the shaft seal(s) can also be sterilized.

A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.