Disclosed are compositions comprised of Oxidized Cellulose (OC), such as oxidized regenerated cellulose (ORC), and an antibiotic comprised of minocycline, methods of preparation thereof and uses thereof.

Disclosed are compositions comprised of Oxidized Cellulose (OC), such as oxidized regenerated cellulose (ORC), and an antibiotic comprised of minocycline, methods of preparation thereof and uses thereof.

The invention relates to antimicrobial and/or antiviral fabric compositions comprising ascorbic acid, citric acid, sodium hypophosphite, or a mixture thereof. The ascorbic acid may be covalently attached to at least one cellulosic portion of the fabric composition. The invention also relates to methods for preparing such fabric compositions.

The invention relates to antimicrobial and/or antiviral fabric compositions comprising ascorbic acid, citric acid, sodium hypophosphite, or a mixture thereof. The ascorbic acid may be covalently attached to at least one cellulosic portion of the fabric composition. The invention also relates to methods for preparing such fabric compositions.

A nano-zinc oxide-supported bacterial cellulose microfiber-alginate fiber composite is described. The composite is obtained by absorbing nano-zinc oxide-supported bacterial cellulose microfibers on an alginate fiber spunlace non-woven fabric; the nano-zinc oxide is uniformly distributed on the surface of the bacterial cellulose microfibers. This composite has good biocompatibility, mechanical properties and water absorption properties, and has a great application prospect in biomedical fields, such as wound dressings, human body repair materials, tissue engineering materials, etc.

A nano-zinc oxide-supported bacterial cellulose microfiber-alginate fiber composite is described. The composite is obtained by absorbing nano-zinc oxide-supported bacterial cellulose microfibers on an alginate fiber spunlace non-woven fabric; the nano-zinc oxide is uniformly distributed on the surface of the bacterial cellulose microfibers. This composite has good biocompatibility, mechanical properties and water absorption properties, and has a great application prospect in biomedical fields, such as wound dressings, human body repair materials, tissue engineering materials, etc.

The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.

The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.

A forming apparatus for forming a plurality of apertures in a nonwoven substrate is provided. The apparatus includes intermeshing members having a first and second member. The first member includes a body portion and a plurality of conical-shaped pins. The plurality of conical-shaped pins each have a first section having a first wall extending from a base portion to a distal portion, at least a portion of the first wall disposed at a first angle greater than 17.5 degrees relative to a central axis. The plurality of conical-shaped pins each have a second section having a second wall extending from a base portion, the base portion extending from the first member body portion, at least a portion of the second wall disposed at a second angle relative to the central axis of each conical-shaped pin, the second angle being different than the first angle and less than 20 degrees.

A forming apparatus for forming a plurality of apertures in a nonwoven substrate is provided. The apparatus includes intermeshing members having a first and second member. The first member includes a body portion and a plurality of conical-shaped pins. The plurality of conical-shaped pins each have a first section having a first wall extending from a base portion to a distal portion, at least a portion of the first wall disposed at a first angle greater than 17.5 degrees relative to a central axis. The plurality of conical-shaped pins each have a second section having a second wall extending from a base portion, the base portion extending from the first member body portion, at least a portion of the second wall disposed at a second angle relative to the central axis of each conical-shaped pin, the second angle being different than the first angle and less than 20 degrees.