The present invention is directed to an absorbable hemostatic patch that utilizes a biocompatible fibrous, fabric substrate that is melt-blown and napped or loosened at the surface, with the substrate having a low-profile, high flexibility, strength and porosity that is suitable for coating cross-linkable active molecules and ultimately effective for use as a hemostat in situations of problematic bleeding.

A tray for processing platelet rich fibrin includes a base having at least one alignment structure, a screen attachment having at least one alignment structure for engagement with the base, and a lid having at least one alignment structure for engagement with the base and the screen attachment. The screen attachment includes a screen offset between the top and bottom surface of the screen. When the screen attachment is placed on the base with the top surface facing upward, the lid is configured to compress a fibrin clot placed on the screen to a first thickness, and when the screen attachment is placed on the base with the bottom surface facing upward the lid is configured to compress a fibrin clot placed on the screen to a second thickness different from the first thickness.

A tray for processing platelet rich fibrin includes a base having at least one alignment structure, a screen attachment having at least one alignment structure for engagement with the base, and a lid having at least one alignment structure for engagement with the base and the screen attachment. The screen attachment includes a screen offset between the top and bottom surface of the screen. When the screen attachment is placed on the base with the top surface facing upward, the lid is configured to compress a fibrin clot placed on the screen to a first thickness, and when the screen attachment is placed on the base with the bottom surface facing upward the lid is configured to compress a fibrin clot placed on the screen to a second thickness different from the first thickness.

The present invention resides in a method for producing jellyfish collagen hydrogels and kits for producing the same. The jellyfish collagen hydrogels can be used in the culture of cells. According to the invention, there is a process for producing jellyfish collagen hydrogels comprising jellyfish collagen fibrils, said process comprising the steps of: mixing a solution of purified jellyfish collagen and an aqueous neutralisation buffer; and incubating the mixture for a sufficient time to enable jellyfish collagen fibrils to form, wherein a cross-linking agent is either added during to mixing step or during or after the incubation of the mixture.

The present disclosure relates to bioactive self-assembling peptides, nanofibers and hydrogels for activating human mast cells. The peptides, nanofibers and hydrogels comprise a self-assembling peptide that mediates self-assembly linked to a MrgX2 agonist peptide; for example, (RADA)4 linked to proadrenomedullin-12 (PAMP-12).

The present disclosure relates to a method for preparing an absorbable haemostatic composition for the body and the haemostatic composition prepared thereby, and the present disclosure is for providing a method for preparing an absorbable haemostatic composition for the body and the haemostatic composition prepared thereby, wherein the haemostatic composition can be used directly on the wound site when bleeding occurs in the surgical area such as surgical operation, trauma, etc. so that hemostasis can be effectively performed, the haemostatic composition can perform wound sealing, tissue repairing promotion, wound surface tissue protection, infection prevention, etc., the haemostatic composition is contained in haemostatic products such as gauze (cotton yarn), sponge, etc. to accelerate the hemostasis speed of the bleeding site and enable rapid hemostasis to be able to shorten the hemostasis time at the same time.

Described herein is a multifunctional polymer-nanoparticle composition for use in wound care applications. Methods of manufacturing the described compositions are also disclosed herein.

Described herein is a multifunctional polymer-nanoparticle composition for use in wound care applications. Methods of manufacturing the described compositions are also disclosed herein.

The present invention describes a composition comprising a mixture of human foetal keratinocyte cells and human foetal fibroblast cells, the ratio between said keratinocyte and fibroblast cells ranging from 0.75 to 2.5, preferably being 1:1 or 7:3. This composition is advantageously included in a bandage, said bandage preferably being sterile and packaged in a container impermeable to microorganisms. The present invention finally concerns the use of this composition as a drug, in particular for treating a skin defect (wound, burn or ulcer).

The present invention describes a composition comprising a mixture of human foetal keratinocyte cells and human foetal fibroblast cells, the ratio between said keratinocyte and fibroblast cells ranging from 0.75 to 2.5, preferably being 1:1 or 7:3. This composition is advantageously included in a bandage, said bandage preferably being sterile and packaged in a container impermeable to microorganisms. The present invention finally concerns the use of this composition as a drug, in particular for treating a skin defect (wound, burn or ulcer).