A method for producing a collagen-containing sheet material, wherein a collagen-containing suspension is dried in such a manner that the collagen settles during drying and forms a transparent skin.

A method for producing a collagen-containing sheet material, wherein a collagen-containing suspension is dried in such a manner that the collagen settles during drying and forms a transparent skin.

Medical devices with a hydrogel layer covalently attached to a portion of the outer surface of the medical device are provided along with methods for applying the coating. The hydrogel layer can include a first polymer species comprising polyethylene glycol (PEG) and a second polymer species. Examples of the second polymer species include PEG and polyacrylamide (PAM). The first and second species can be at least partially cross-linked. Methods for forming the hydrogel coatings on the medical devices are provided including nucleophilic conjugate reactions, such as Click reactions.

An absorbent article includes a chassis comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet. The absorbent core contains superabsorbent polymer material and about 10% or less by weight of cellulosic fibers. The backsheet comprises a film comprising a plurality of micropores. The film comprises odor absorbing material disposed in one or more of the micropores.

An absorbent article includes a chassis comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet. The absorbent core contains superabsorbent polymer material and about 10% or less by weight of cellulosic fibers. The backsheet comprises a film comprising a plurality of micropores. The film comprises odor absorbing material disposed in one or more of the micropores.

A wound dressing material comprises a porous flexible foam core, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the porous flexible foam core and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

A wound dressing material comprises a porous flexible foam core, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the porous flexible foam core and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a water-insoluble polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.

A method for preparing a three-dimensional chitosan/silver composite scaffold includes mixing an acidic aqueous chitosan solution including protonated chitosan and a deposition accelerating agent being a soluble silver salt, spacedly disposing a cathode and an anode in the resultant suspension, and applying an electric field to the cathode and the anode so that the suspension undergoes electrodeposition. The suspension has a protonated chitosan concentration ranging from 0.7 to 2.8 w/v %, and a molarity of silver ions ranging from 4 to 60 mM. The composite scaffold prepared has columnar through-holes extending in a same extension direction and each having opposite first and second openings with the latter not less in width.

An absorbent wound dressing comprises a hydrophilic porous substrate and polymer-stabilized silver nanoparticles distributed throughout the porous substrate. The silver nanoparticles have a particle size d.sub.50 in the range of about 45 nm to about 85 nm and the silver nanoparticles are present in the substrate in an amount of about 0.16% to about 1.5% by weight of the total weight of the substrate. The wound dressing produces a 7-day log reduction of 4 or more for bacteria in accordance with the Modified AATCC Test Method 100. The wound dressing is also non-cytotoxic in accordance with ISO 10993-5 standard procedure for medical device cytotoxicity assessment.