The present invention relates to a device and a method. The device of the present invention comprising a patch comprising: a substrate, and an adhesive on the substrate. Further, the patch is configured to be attached to a skin via the adhesive to form a pocket between the patch and the skin, to allow introduction of a material into the pocket, and to hold the material within the pocket.

Liquid activated ink formulations comprising a liquid activated dye, a hydrochromic ionic compound, an opacifier, and a solvent.

Liquid activated ink formulations comprising a liquid activated dye, a hydrochromic ionic compound, an opacifier, and a solvent.

Provided herein are methods for making foam materials and foam material products having a polyurethane foam matrix defining a plurality of pores, a hydrophilic agent retained within at least a portion of the pores for improving an absorption of the foam material, a salt retained within at least a portion of the pores in an amount sufficient to render the foam material isotonic, a surfactant retained within at least a portion of the pores in an amount sufficient to be released upon contact with a moist surface. Also provided herein are methods for making a multilayer foam by casting a second foam layer on a first foam layer substrate and compressing the second foam layer before the second layer is fully cured to form an interface layer in situ.

Provided herein are methods for making foam materials and foam material products having a polyurethane foam matrix defining a plurality of pores, a hydrophilic agent retained within at least a portion of the pores for improving an absorption of the foam material, a salt retained within at least a portion of the pores in an amount sufficient to render the foam material isotonic, a surfactant retained within at least a portion of the pores in an amount sufficient to be released upon contact with a moist surface. Also provided herein are methods for making a multilayer foam by casting a second foam layer on a first foam layer substrate and compressing the second foam layer before the second layer is fully cured to form an interface layer in situ.

The present application relates to an electronic wetness-sensing absorbent article and related methods. The electronic wetness-sensing absorbent article includes a flexible waterproof thin film; at least two mutually separated and insulated flexible electrodes disposed on one surface of the flexible waterproof thin film; a water-permeable braided fabric layer; and an absorbent layer disposed on the other surface of the flexible waterproof thin film, located between the flexible waterproof thin film and the water-permeable braided fabric layer, and adapted to absorb a liquid entering from the water-permeable braided fabric layer. The flexible waterproof thin film, the flexible electrodes, and the liquid contained in the absorbent layer form a non-polar variable electrolytic capacitor. The wetness state of the electronic wetness-sensing absorbent article is obtained by detecting the capacitance value of the variable electrolytic capacitor and change thereof.

The present application relates to an electronic wetness-sensing absorbent article and related methods. The electronic wetness-sensing absorbent article includes a flexible waterproof thin film; at least two mutually separated and insulated flexible electrodes disposed on one surface of the flexible waterproof thin film; a water-permeable braided fabric layer; and an absorbent layer disposed on the other surface of the flexible waterproof thin film, located between the flexible waterproof thin film and the water-permeable braided fabric layer, and adapted to absorb a liquid entering from the water-permeable braided fabric layer. The flexible waterproof thin film, the flexible electrodes, and the liquid contained in the absorbent layer form a non-polar variable electrolytic capacitor. The wetness state of the electronic wetness-sensing absorbent article is obtained by detecting the capacitance value of the variable electrolytic capacitor and change thereof.

Described are systems and methods which can be used to indicate the period of time elapsed since the occurrence of a triggering event. More particularly, this application relates to systems and methods which can be used to visually indicate the time period elapsed since an article has been removed from its packaging. The system can include an indicator disposed on or within the article and a trigger disposed within the receptacle and in contact with the indicator. The article may be enclosed within a sealable receptacle of the package. The indicator is responsive to a change in a concentration of the trigger in contact with the indicator. The removal of the article from the receptacle can induce a change in concentration of the trigger in contact with the indicator. The change in the concentration of the trigger can induce a change in color in the indicator. The color change indicates a predetermined period of time has elapsed since the article has been removed from the receptacle. The predetermined period of time is from 30 minutes to 30 days, such as from 1 hour to 30 days.

The invention relates to a functional wound dressing being able to detect and indicate the state of the wound, in particular with regard to an infection which is reported to be frequently associated with poorly healing wounds, such as chronic wounds. The present wound dressing can be used in moist wound healing and contains a substance being able to absorb wound exudate from the wound and to provide moisture to the wound.

Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.